NEW SPECIAL COURSE

 Tuesday, March 1, 2011   —  8:00 a.m. - 5:00 p.m.

BASIC PRINCIPLES IN CYTOLOGY



COURSE DIRECTOR:
Tarik M. Elsheikh, M.D.
Ball Memorial Hospital, PA Labs
Muncie, IN

Course Description
Cytology has grown to play a major role in tumor diagnosis. Surgical pathologists who may have had limited or no specialized training in cytology, are increasingly asked to render more definitive diagnoses based on small cytological samples, and/or provide immediate interpretations for radiology-guided FNA's. This special course emphasizes the essentials and basics of diagnostic cytology, and is intended for surgical pathologists who wish to be introduced or re- introduced to the discipline of cytology, or those who are interested in a "refresher" in general basic cytology. This course is also ideal for residents in training, and those preparing for boards or in-service exams. The faculty is made up of experts in the field, who will cover the most commonly encountered specimen types, including gynecologic, exfoliative, and FNA cytology. They will present detailed diagnostic criteria, adequacy requirements, differential diagnosis, and histopathologic correlation. Potential pitfalls, as well as the value of ancillary studies, including immunohistochemistry and molecular testing, will be discussed when relevant. There will be an ample opportunity for questions and audience participation. This course may also serve as an introduction to other cytology workshops or courses, which often tend to be of an advanced level, and more geared towards pathologists with strong cytology background. The goal of this course is for the participants to become less intimidated by cytologic samples, and more confidently diagnose commonly encountered lesions, while still recognizing potential limitations and pitfalls. All registrants will receive a detailed text syllabus, in addition to a CD containing the PowerPoint lectures and images.

Course Objectives:

  • Review essentials and basics of diagnostic cytology, including gynecologic, exfoliative, and FAN cytology.

  • Review detailed diagnostic criteria, adequacy requirements, and histologic correlation for different organ systems and specimen types, including normal cytology and more commonly encountered lesions.

  • Recognize potential limitations, common pitfalls and differential diagnostic considerations.

  • Appreciate the value of ancillary studies, including immunohistochemistry and molecular testing in the diagnostic workup.
Introduction
Tarik M. Elsheikh, M.D., Ball Memorial Hospital, PA Labs, Muncie, IN
Fundamentals of Cytology
Tarik M. Elsheikh, M.D., Ball memorial Hospital, PA Labs, Muncie, IN
  • Review various cell types commonly encountered in cytologic specimens.

  • Review general cytologic features of benign tumors, especially nuclear features.

  • Review diagnostic cytologic features of malignancy, including architecture and most importantly, nuclear changes.

  • Discuss cytology of common specific malignancies such as squamous, adeno, small cell, and undifferentiated carcinoma.

  • Recognize common pitfalls and mimickers of malignancy, including reactive/inflammatory and degenerative changes.
Cervical Cytology
Edmund S. Cibas, M.D., Brigham and Women's Hospital and Harvard Medical School, Boston, MA
  • To understand the role of cervical cytology in screening for cervical cancer and its precursors.

  • To understand common terminology for reporting Pap test results.

  • To know the criteria for judging specimen adequacy.

  • To be able to recognize the commonly encountered infectious organisms.

  • To be able to recognize squamous and glandular lesions on a Pap test and their histologic correlates.
Effusion Cytology
Jan F. Silverman, M.D., Allegheny General Hospital and Temple University School of Medicine, Pittsburgh, PA
  • The participants will learn a pattern recognition approach for effusion cytology diagnosis.

  • The participants will learn the appropriate use of ancillary studies in the work up of problematic effusion cytology.

  • The participants will appreciate the value of cytologic and clinical correlation including the importance of age, gender, and site of the effusion for correct diagnosis.
Urine Cytology
Andrew Renshaw, M.D., Baptist Hospital, Miami, FL
  • Focus on a practical approach to urine cytology, including difficult or borderline cases.

  • Know not to waste time diagnosing low grade lesions.

  • Recognize coy cells and their significance.

  • Appreciate the range of degeneration that is common in urothelial carcinoma.
Basic Thyroid Cytomorphology
Zubair W. Baloch, M.D., Ph.D., Hospital of the University of Pennsylvania, Philadelphia, PA
  • Discuss and illustrate the basic concepts in thyroid cytomorphology.

  • Generate a cytologic differential diagnosis with histologic correlation of commonly encountered thyroid lesions.

  • Recognize the overlapping architectural and cytologic features of benign and malignant thyroid lesions.
Basics in Lymph Node Cytopathology
Paul E. Wakely, Jr., M.D., The Ohio State University College of Medicine, Columbus, OH
  • Recognize the cytomorphology of the benign lymph node and the limitations, advantages, and adequacy of this technique.

  • Differentiate among the various infectious and other non-neoplastic conditions of an enlarged lymph node.

  • Recognize and differentiate the FNA cytopathology of various lymphoproliferative malignancies according to the most recent WHO classification.

  • Define the application of ancillary techniques to the cytopathologic diagnosis of malignant lymphoma.

  • Identify cytopathologic imitators of malignant lymphoma and various non-lymphoid lesions metastatic to lymph nodes.
Respiratory Cytopathology
Celeste N. Powers, M.D., Ph.D., Virginia Commonwealth University Health System, Richmond, VA
  • To review the basic cytomorphologic criteria for common infectious processes and neoplasms amenable to cytodiagnosis.

  • To review the use of the Diff Quik and other special stains in the diagnosis of infectious agents.

  • To discuss the pitfalls and mimics associated with primary lung malignancies.

  • To review the utility of immunohistochemistry in the diagnosis and subclassification of non-small cell lung carcinoma.
FNA Biopsy of Liver
Richard M. DeMay, M.D., The University of Chicago, Chicago, IL
  • Learn normal cytology of the liver.

  • Learn key diagnostic features of benign and malignant liver lesions.

  • Learn to distinguish hepatocellular carcinoma from metastatic carcin.
Basic Principles of Pancreatic Cytology
Martha Bishop Pitman, M.D., Harvard Medical School and Massachusetts General Hospital, Boston, MA
  • Recognize normal pancreatic acinar and ductal cells.

  • Distinguish gastrointestinal contamination from the stomach and duodenum from lesional epithelium.

  • Understand the criteria for the common tumors of the pancreas.

  • Understand the benefits and limitations of ancillary testing in diagnosis.
Question and Answer Session