POSTER SESSION I STOWELL-ORBISON/AUTOPSY and SURGICAL PATHOLOGY AWARDS COMPETITION Monday, February 28, 2011   —  9:30 AM - 12:00 Noon Exhibit Hall Click on the blue numbers in parentheses to display abstracts. Click the button next to any title to add to Itinerary Planner... HEMATOPATHOLOGY Poster# Title and Authors Itinerary Planner 160 Azacitidine Treatment of MDS/AML: Effect on Immunophenotyping by Flow Cytometry and Associated Cytogenetic Findings. (1382) A Torabi, JZ Huang, VK Douglas-Nikitin, MD Smith - William Beaumont Hospital, Royal Oak, MI Add 161 Myeloid Neoplasms Secondary to Plasma Cell Myeloma: Clinicopathological Study of 11 Cases. (1349) DM Reddi, EL Boswell, CM Lu, E Wang - Duke University Medical Center, Durham, NC; University of California San Francisco Add 162 Myelodysplastic Syndrome with DEL(5q): A Comprehensive Analysis of 24 Cases from One Institution. (1386) S Verma, JT Geyer, S Subramaniyam, S Mathew, R Espinal-Witter, DM Knowles, A Orazi - Weill Cornell Medical College, New York Add 163 Degradation of BCL-XL by Activated p38 Pathway Plays a Key Role in Myelodysplastic Syndromes (MDSs) . Revealed by Reverse Phase Protein Array (RPPA) and Computational Mathematical Model. (1411) L Zhang, J Wen, Y Zu, A Ewton, H Peng, X Zhou, C-C Chang - Methodist Hospital & Weill Cornell Medical College, Houston, TX; Methodist Hospital Research Institute, Houston, TX Add 164 Integrative Analysis of Next Generation Sequencing for Small Non-Coding RNAs and Transcriptional Regulation in Myelodysplastic Syndromes. (1268) JM Gonzalez-Berjon, D Beck, S Ayers, J Wen, M Brandl, T Pham, P Webb, X Zhou, CC Chang - The Methodist Hospital and The Methodist Hospital Research Institute, Houston, TX; The University of New South Wales, Canberra, ACT, Australia; The Methodist Hospital Research Institute, Houston, TX; Weill Cornell Medical College, New York, NY Add 165 Short Term Imatinib Therapy Promotes Bone Formation in Patients with Chronic Myelogenous Leukemia (CML) Independent of Cytogenetic Response. (1280) D Hoehn, L Medeiros, C Bueso-Ramos - UT M.D. Anderson Cancer Center, Houston, TX Add 166 β-Catenin Expression Is Increased in Imatinib-Resistant Chronic Myelogenous Leukemia. (1416) X Zhang, L Moscinski, WW Bulkeley, B Shah, J Pinilla-Ibarz, L Zhang - University of South Florida College of Medicine, Tampa; Moffitt Cancer Center and Research Center, Tampa, FL Add 167 Acquired Cytogenetic Aberrations in Philadelphia Chromosome Negative Cells from Patients with Chronic Myelogenous Leukemia Not Associated with Definitive Myelodysplasia. (1224) WW Bulkeley, B Shah, X Zhang, J Pinilla-Ibarz, L Zhang - University of South Florida College of Medicine, Tampa; Moffitt Cancer Center and Research Center, Tampa, FL Add 168 Fibrotic Transformation of Polycythemia Vera & Essential Thrombocythemia Is Biologically Indistinguishable from Primary Myelofibrosis. (1357) NA Sangle, C Teman, S Perkins, A Wilson, D Bahler, J Prchal, ME Salama - University of Utah & ARUP Laboratories, Salt Lake City Add 169 Development of Monocytosis in Patients with Primary Myelofibrosis Indicates an Accelerated Phase of the Disease. (1256) R Espinal-Witter, JT Geyer, S Verma, DM Knowles, A Orazi - Weill Cornell Medical Center, New York, NY Add 170 Paracortical Population of CD11c+CD8-DC Dendritic Cells in Angioimmunoblastic T-Cell Lymphoma. (1243) S Daniel, V Ghali - St. Lukes Roosevelt Hospital, New York, NY; Beth Israel Medical Center, New York, NY Add 171 Primary Mucosal CD30-Positive T-Cell Lymphoproliferative Disorders Have Clinicopathologic Features Similar to Primary Cutaneous Cases. (1359) AP Sciallis, ME Law, DJ Inwards, WR Macon, A Dogan, AL Feldman - Mayo Clinic, Rochester, MN Add 172 Opposing Effects of Vitamin D/Vitamin D Receptor and Interferon Regulatory Factor-4 in Anaplastic Large Cell Lymphomas. (1296) S Kip, JC Porcher, JR Cerhan, SM Ansell, A Dogan, AL Feldman - Mayo Clinic, Rochester, MN Add 173 Distinct Populations of CD8+/CD57+ Large Granular Lymphocytes Are Associated with T-Cell Monoclonality and Define a Subset of Clinically and Pathologically Significant Patients: A Case-Control Study of 70 Patients with Large Granular Lymphocytic Proliferations. (1328) RS Ohgami, IT Pereira, JL Zehnder, DA Arber - Stanford University Medical Center, CA Add 174 Down Regulation of Oct-2 Expression in Non-Secretory Plasma Cell Myeloma Is Associated with Decreased Immunoglobulin Transcription. (1244) S Daniel, X Chen, E Poje, E Hyjek, J Vardiman - University of Chicago, IL; William Beaumont Hospital, Troy, MI; Memorial Medical Center, Springfield, IL Add 175 CD5-Negative Mantle Cell Lymphoma, a Potential Diagnostic Pitfall. A Single Institution's Experience in past 5 Years. (1401) X Wu, HS Edmund, VVB Reddy - University of Alabama at Birmingham; Cunningham Pathology, St Vincent's Birmingham, AL Add 176 Thyroid Lymphomas Express Similar Immunoglobulin VH Genes. (1211) N Aggarwal, TJ Whitney, JA Kant, SH Swerdlow, DW Bahler - University of Pittsburgh Medical Center, PA; University of Utah, Salt Lake City Add 177 A New Biological Model Based on Immunohistochemistry Predicts Survival in Patients with Diffuse Large B-Cell Lymphoma. (1339) AM Perry, PN Meyer, TM Cardesa-Salzmann, LM Smith, L Colomo, AL Guillermo, E Campo, TC Greiner, J Delabie, RD Gascoyne, L Rimsza, ES Jaffe, G Ott, A Rosenwald, RM Braziel, R Tubb, J Cook, L Staudt, J Connors, JM Vose, WC Chan, DD Weisenburger - University of Nebraska Medical Center for the Lymphoma/Leukemia Molecular Profiling Project, Omaha Add 178 Inhibition of BCL6 as a Mechanism To Target Therapy-Resistant Malignant Cells. (1399) K Wolniak, N Mohindra, T Lax, L Cerchietti, A Melnick, J Licht - Northwestern University, Chicago, IL; Children's Memorial Hospital, Chicago, IL; Weill Cornell Medical College, New York, NY Add 179 Gene and Protein Isoform Expression Analysis of the BCL-6 Associated Transcriptional Corepressor MTA3 in B- lineage Cells. (1371) DV Spencer, CL Foulks, CM Geigerman, PS Akl, AY Lai, PA Wade, DL Jaye, CE Hill - Emory University, Atlanta, GA; NIEHS, Research Triangle Park, NC Add 180 Prognostic Value of Fatty Acid Synthase and Spot14 in Diffuse Large B-Cell Lymphoma. (1245) OV Danilova, HM Froehlich, T Hammour, NB Kuemmerle, NB Levy, WB Kinlaw, P Kaur - Dartmouth-Hitchcock Medical Center, Lebanon, NH; Maine Medical Center, Portland; Dartmouth Medical School, Hanover, NH; Norris Cotton Cancer Center, Lebanon, NH Add 181 Clinicopathologic Features of Double Hit Lymphomas with BCL6 and MYC Gene Rearrangements. (1340) RK Pillai, M Sathanoori, SH Swerdlow - University of Pittsburgh Medical Center, PA Add 182 Characterization of B-Cell Lymphoma Unclassifiable with Features Intermediate between Diffuse Large B-Cell Lymphoma and Burkitt's Lymphoma: A Ten Year Retrospective Review. (1254) L Edwards, V Bhagirath, E Krakow, C Keng, A Lytwyn, C Ross, L Thebane, E Cheng, M Sur - McMaster University, Hamilton, ON, Canada Add 183 Clinical Significance of CMYC Rearrangement in Diffuse Large B-Cell Lymphoma. (1227) GC Caponetti, B Dave, L Smith, P Meyer, M Bast, P Bierman, G Bociek, J Vose, JO Armitage, P Aoun, K Fu, T Greiner, WC Chan, D Weisenburger - University of Nebraska Medical Center, Omaha Add 184 MYC Copy Number and Signal Clusters by Colormetric In-Situ Hybridization (CISH) in Diffuse Large B-Cell Lymphoma (DLBCL). (1383) CM Valentino, NA Johnson, PJ Brunhoeber, H Nitta, RD Gascoyne, TM Grogan, LM Rimsza - University of Arizona School of Medicine, Tucson; British Columbia Cancer Agency, Vancouver, Canada; Ventana Medical Systems Inc., Tucson, AZ; McGill University, Montreal, Canada Add 185 The p53 Pathway Is Frequently Deregulated in Pediatric Burkitt Lymphoma, but over Expression of MDM2 or HDM4 Is Not a Common Mechanism. (1303) V Leventaki, V Rodic, MS Jahromi, JM Downie, SR Tripp, MG Bayerl, SL Perkins, P Barnette, JD Schiffman, RR Miles - University of Utah, Salt Lake City; ARUP Laboratories, Salt Lake City, UT; Penn State College of Medicine, Hershey, PA Add 186 Plasmablastic Differentiation in Low Grade B-Cell Lymphomas: An Unusual Histological Transformation. (1313) D Martinez, L Colomo, M Rozman, A Valera, E Gine, A Lopez-Guillermo, S Martinez, K Warzocha, T Robak, M Czader, E Campo, A Martinez - Hospital Clinic, University of Barcelona, Spain; Hospital Universitari Joan XXIII, Tarragona, Spain; Institute of Hematology, Warsaw, Poland; Medical University of Lodz, Poland; University of Indiana, Indianapolis Add 187 Biologic Characteristics of Monoclonal B-Cell Lymphocytosis Detected by Routine Clinical Flow Cytometric Testing. (1306) Z Li, SH Swerdlow, U Surti, FE Craig - Univ. of Pittsburgh Medical Center, PA Add 188 Single Nucleotide Polymorphism (SNP) Array Genomic Profiling Identified High Prevalence of Clonal Diversity Associated with Clinical Progress in Chronic Lymphocytic Leukemia. (1415) L Zhang, I Znoyko, SE Self, DJ Wolff - Medical University of South Carolina, Charleston Add 189 Expression of CD137 Protein in Select Hematopoietic Tumors: Implications for Anti-CD137 Immunomodulatory Therapy. (1214) MW Anderson, AG Freud, S Zhao, AA Alizadeh, HE Kohrt, R Warnke, R Levy, Y Natkunam - Stanford, Stanford, CA Add 190 Downregulation of A20 Tumor Suppressor Gene Product in Classical Hodgkin Lymphomas and Subtypes of Non-Hodgkin Lymphomas. (1260) AM Gabali, F Keyoumarsi, TG Dafydd, K Elenitoba-Johnson, MS Lim - The University of Michigan, Ann Arbor Add 191 ALDH1, Carbonic Anhydrase 1, and CD2AP: Novel, Diagnostically Useful Immunohistochemical Markers To Identify Erythroid Precursors in Bone Marrow Biopsies. (1353) MA Rollins-Raval, K Fuhrer, T Marafioti, CG Roth - University of Pittsburgh Medical Center, PA; University College London, United Kingdom Add 192 Detection of T Cell Clonality at Diagnosis, in Small Samples and Monitoring of Minimal Residual Disaease (MRD) Using TCR-V Beta Repertoire Analysis. (1381) PR Tembhare, CM Yuan, L Xi, J Janik, J Morris, M Raffeld, M Stetler-Stevenson - Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD; Center for Cancer Research, National Cancer Institute, Mark O. Hatfield Clinical Research Center, National Institutes of Health, Bethesda, MD Add