POSTER SESSION II Monday, February 28, 2011   —  1:00 PM - 4:30 PM Exhibit Hall Click on the blue numbers in parentheses to display abstracts. Click the button next to any title to add to Itinerary Planner... SPECIAL TOPICS - PAN-GENOMIC/PAN-PROTEOMIC APPROACHES TO DISEASES Poster# Title and Authors Itinerary Planner 232 Platelet Cloaking of Cancer Cells Alters Apoptotic Potential: Implications for Metastasis. (1878) DJ Crowley, PA Smyth, CD Spillane, SA O'Toole, K Egan, D Kenny, OM Sheils, JJ O'Leary - Trinity College Dublin, Ireland; Royal College of Surgeons in Ireland, Dublin, Ireland Add 233 Copy Number Variations among Renal Cell Neoplasms Exhibit Heterogenity Across Subtypes, Homogeneity within Subtypes and Correlated Changes in Transcriptional Profiles. (1888) JM Krill-Burger, MA Lyons, CM Sciulli, LA Kelly, SI Bastacky, R Dhir, AV Parwani, WA LaFramboise - University of Pittsburgh, PA Add 234 Recurrent Cytogenetic Alterations in Radiation Induced (RI) Abdominal Malignant Mesothelioma (AMM). (1900) AN Sireci, B Levy, T Robert, JL Chen, N Odelia, BC Alain - Columbia University Medical Center, New York, NY Add 235 Development and Analytical Validation of a Quantitative Tissue-Based Assay for Phospho-Smad2 (Ser465/467) in Glioblastoma Multiforme: A Potential Biomarker of TGF-β Pathway Activation. (1886) TR Holzer, M Gustavson, R Pinard, J Christiansen, L Graves, SP Myrand, SK Kadam, MMF Lahn, JT Brandt, JM Yingling, A Nasir - Eli Lilly and Co., Indianapolis, IN; HistoRx, Branford, CT Add 236 Integrated Signature of PI3K Pathway Activation in Prostate Cancer. (1892) NE Martin, JA Sinnott, S Finn, G Fedele, MJ Stampfer, O Andren, S-O Andersson, L Mucci, M Loda - Dana Farber Cancer Institute & Brigham and Women's Hospital, Boston, MA; Orebro University Hospital, Sweden; Harvard School of Public Health, Boston, MA Add 237 Expression Profiling of Holoclone and Non-Holoclone Derived Cell Lineage in Prostate Cancer. (1899) YM Salley, MF Gallagher, PC Smyth, CM Martin, OM Sheils, JJ O'Leary - University of Dublin, Trinity College, Dublin, Ireland Add 238 TLR4 and MyD88 Expression in Cancer Stem Cells. (1876) AA Cooke, MF Gallagher, SA O'Toole, CM Martin, OM Sheils, JJ O'Leary - University of Dublin, Trinity College, College Green, Ireland Add 239 Genome-Wide Massively Parallel Sequencing Using SOLiD. 4 of Formalin Fixed Paraffin Embedded Prostate Cancer Tissue. (1894) P Nikolov, R Menon, M Brown, V Scheble, F Fend, D Boehm, S Biskup, S Perner - University Hospital Bonn, Germany; University Hospital Tuebingen, Germany; CeGaT GmbH, Tuebingen, Germany; University of Tuebingen Medical Center II, Germany Add 240 Detection of Prognostically Significant AML Translocations and Single Base Mutations by Next Generation Sequencing. (1879) EJ Duncavage, HJ Abel, S South, JD Pfeifer - University of Utah, Salt Lake City; Washington University, St Louis, MO Add 241 High Levels of Necrosis in TCGA Glioblastoma Samples Are Associated with the Mesenchymal Gene Expression Class and Characterized by Enhanced Expression of Master Transcriptional Regulators of Mesenchymal Transition. (1872) DJ Brat, DA Gutman, LAD Cooper, J Kong, C Chisolm, EG Van Meir, JH Saltz, CS Moreno - Emory University School of Medicine, Atlanta, GA Add 242 Rapid and Reliable Method To Isolate Nuclei from FFPE Specimens for Genomic-Scale Molecular Profiling. (1887) K Killian, L Wang, B Walker, A Glatfelter, WI Smith, PS Meltzer - National Cancer Institute, Bethesda, MD; Suburban Hospital, Bethesda, MD Add 243 Gene Expression Profiling of Colonic Serrated Epithelial Lesions. (1882) TS Giles, D Chiao, E Stelow, P Pramoonjago, CA Moskaluk - University of Virginia, Charlottesville Add 244 Comparing Two Different Platforms for Analyzing Genomic DNA Micro-Array in Mental Retardation. (1889) A Leifer, Q Pan - Montefiore Medical Center, Bronx, NY Add 245 The Epithelial Mesenchymal Transition (EMT) Profile of Platelet Cloaked Cancer Cells. (1877) DJ Crowley, PA Smyth, SA O'Toole, K Egan, D Kenny, OM Sheils, JJ O'Leary - Trinity College Dublin, Ireland; Royal College of Surgeons Ireland, Dublin, Ireland Add 246 FGFR2 Alterations in Endometrial Carcinoma. (1881) S Gatius, A Azueta, A Velasco, M Santacana, J Pallares, X Matias-Guiu - Hospital Universitari Arnau de Vilanova, University of Lleida, IRBLLEIDA, Spain Add 247 microRNA Profiling in Lung Cancer Diagnosis and Staging. (1901) CC Solomides, B Evans, P Li, V Kumar, R Vadigepalli, SC Peiper, Z Wang - Thomas Jefferson University, Philadelphia, PA Add 248 Increased Expression of MicroRNA-210 in Microsatellite Instability High Endometrial Carcinoma and Its Potential Role in DNA Damage Repair. (1890) D Ma, Z Chen, H Cheng, B Djordjevic, KP Patel, MG Luthra, BA Barkoh, S-S Xie, S Ma, G Chen, J Medeiros, R Broaddus, R Luthra - The University of Texas M. D. Anderson Cancer Center Center, Houston Add 249 Altered microRNA Expression in Adenocarcinoma of Lung from Smokers and Never-Smokers. (1884) M Guo, M Huang, GA Calin, KR Hess, W Zhang - The University of Texas M.D. Anderson Cancer Center, Houston; Fox Chase Cancer Center, Philadelphia, PA Add 250 Tissue Metablomics by High-Resolution 1H NMR Spectroscopy: Discovery of Colon Cancer-Specific Metabolomic Biomarkers. (1897) MH Roehrl, SS Wang, JY Wang - Boston Medical Center, MA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA Add 251 The Human Protein Atlas. (1896) F Ponten - Rudbeck Laboratory, Uppsala University, Sweden Add 252 Application of Reverse Phase Protein Lysate Array (RPPA) to Formalin-Fixed, Paraffin-Embedded Tissues. (1873) R Broaddus, S-S Xie, C Wei, E Euscher - M.D. Anderson Cancer Center, Houston, TX Add 253 Bone Marrow Aspirate Paraffin Blocks as Reliable Source for Long-Term Protein Preservation. (1893) M Nassiri, S Ramos, A Morales - Indiana University School of Medicine, Indianapolis; Univerity of Miami, FL Add