This short course will enable confident diagnosis of various reactive, benign and neoplastic glandular lesions on Pap Tests. The course discussion will evolve around 10 wide-ranging cases. Emphasis will be placed on morphological appearances of glandular lesions as seen on liquid-based preparations. Comparative analysis of various lesions on conventional smears, common artifacts, diagnostic dilemmas and potential pitfalls will be highlighted. The role of HPV-testing in endocervical lesions will be outlined. Current diagnostic and management guidelines will be reviewed. The importance of histological and clinical correlation will be emphasized. Related quality assurance issues will be addressed. Pre-registrants will be able to view virtual slides and still images from the 10 illustrative cases, and attempt related multiple-choice questions, in advance (at www.uscap.org). A syllabus will be distributed to registrants at the meeting. An interactive approach with the audience, and brief question-answer and discussion periods will ensure audience participation. After the meeting, all participants will receive web access to the PowerPoint presentation given at the USCAP Annual Meeting along with the text portion of the syllabus. Practicing pathologists, pathologists-in-training and cytotechnologists will benefit from this course.

Upon completion of the course, the participants will be able to: 1) diagnose various glandular lesions on liquid-based Pap Tests; 2) recognize differences in appearance of these lesions on conventional and liquid-based preparations; 3) utilize ancillary tools, including immunocytochemistry and HPV-testing; 4) realize limitations of cytological diagnoses; and 5) understand current management guidelines.

This course may be used for CME credits or SAM credits.