SPECIAL COURSE Monday, February 28, 2011   —  7:50 AM - 1:00 PM Convention Center 001 A/B A PRACTICAL GUIDE TO MOLECULAR TESTING IN CANCER Click the button above to add this event to your Itinerary Planner... COURSE DIRECTORS: Julia A. Bridge, M.D., FACMG Department of Pathology & Laboratory Medicine University of Nebraska Medical Center Omaha, NE Accumulating discoveries of the biological mechanisms that control cell growth and differentiation, and developments in the clinical management of cancer, continue to expand the role of molecular technology in diagnostic surgical pathology. In this course, the fundamental principles of molecular pathology in cancer and their application to laboratory medicine will be emphasized in a format designed to be practical and straightforward. Specifically, this course is aimed at providing pathologists with a foundation in the practice of oncologic molecular pathology to include: nomenclature, commonly used techniques and their specimen requirements, assay selection and indications, diagnostic and prognostic utility, test turn-around-times, and quality assurance issues. Select cases may be presented to illustrate use in routine practice and serve as useful paradigms. Moreover, specific areas will be highlighted in which major advances can be expected and to which the key principles learned can be applied. Course Objectives: To present an overview of the central genetic principles of oncologic molecular tests commonly used in the practice of pathology. To provide participants with a working knowledge of tests available in oncologic molecular pathology as well as their application and interpretation in screening, diagnosis, monitoring, and treatment of cancer AGENDA 7:50 Introduction Julia A. Bridge, M.D., FACMG 8:00 Clinical Cytogenetic and Molecular Genetic Testing in Bone and Soft Tissue Tumors Julia A. Bridge, MD, University of Nebraska Medical Center, Omaha, NE 8:40 Breast Cancer: Molecular Pathology as Applied to Clinical Practice Michael F. Press, MD, PhD, Keck School of Medicine, University of Southern California, Los Angeles, CA 9:10 Molecular Markers for Targeted Lung Cancer Therapy John Iafrate, MD, PhD, Massachusetts General Hospital, Boston, MA 9:40 Molecular Pathology of Neoplasms of the Kidney and Urinary Tract Victor E. Reuter, MD, Memorial Sloan Kettering Cancer Center, New York, NY 10:10 Coffee Break 10:40 Molecular Diagnostics of Lymphoma: Assays for Classification, Outcome Prediction and Therapy Response Dan Jones, MD, PhD, Quest Diagnostics Nichols Institute, Chantilly, VA 11:20 GIST and Melanoma: The KIT Connection and So Much More Alexander Lazar, MD,PhD, University of Texas M. D. Anderson Cancer Center, Houston, TX 11:50 Colorectal Cancer: Molecular Testing for the Surgical Pathologist Kevin C. Halling, MD, PhD, Mayo Clinic, Rochester, MN 12:20 Molecular Diagnostics of Gliomas Arie Perry, M.D, University of California, San Francisco (UCSF), San Francisco, CA 12:50 Question Period and Concluding Remarks 1:00 Adjourn