—  SPECIALTY CONFERENCE  —

Gynecologic Pathology

Case 3 - PRO: The Diagnosis of the Usual Complete or Partial Mole Requires an Immune and/or Molecular Workup Rather Than Just a Good H&E Stain and Some Experience

Brigitte M. Ronnett, Johns Hopkins Hospital, Baltimore, MD





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Clinical History
Case A: 34 year old; “R/O partial mole”.

Case B: 35 year old; Estimated gestational age = 6-7 weeks; β-HCG = 105,599 mIU/mL; Ultrasound: “multicystic mass filling endometrium, possible small abnormal gestational sac, suspicious for hydatidiform mole—could be partial”.

Case C: 49 year old; Incomplete abortion.

Case D: 19 year old; Recurrent missed abortions.

Case E: 41 year old; Rising quantitative β-HCG; Ultrasound: no evidence of fetal heart tones or definite fetal pole; R/O molar pregnancy.


Case 3A - Figure 1

Case 3A - Figure 2

Case 3A - Figure 3

Case 3B - Figure 1

Case 3B - Figure 2

Case 3B - Figure 3

Case 3C - Figure 1

Case 3C - Figure 2

Case 3C - Figure 3

Case 3D - Figure 1

Case 3D - Figure 2

Case 3D - Figure 3

Case 3E - Figure 1

Case 3E - Figure 2

Case 3E - Figure 3