Comprehensive Molecular Oncogenomic Profiling & microRNA Analysis of Prostate Cancer Seema Sethi, Dejuan Kong, Greg Dyson, Wael Sakr, Fazlul Sarkar , Wayne State University, Detroit, MI
	Identification of Anaerobic Bacteria Using MALDI-TOF MS Bruker Biotyper System Yen-Michael S Hsu, Carey-Ann D Burnham , Washington University School of Medicine, Saint Louis, MO
	The Effects of Oxidative Stress on Dendritic Cell Migration and T-Cell Interaction Ibrahim Batal, Jamil Azzi, Marwan Mounayar, Bechara Mfarrej, Reza Abdi , Brigham and Women's Hospital, Boston, MA
	Therapeutic Combination of Novel Mitochondrial Hsp90 Inhibitors, Gamitrinibs, with Phosphatidylinositol 3-Kinase Inhibitors Exerts Therapeutic Activity Against Glioblastoma In Vivo and In Vitro without Significant Toxicity Markus D Siegelin, Dario C Altieri , Columbia University College of Physicians & Surgeons, New York, NY; The Wistar Institute Cancer Center, Philadelphia, PA

	"Calling Cards" Is a Novel Next-Gen Sequencing Approach That Identifies SRY Targets Gabriel A Bien-Willner, David Mayhew, Robi Mitra , Washington University School of Medicine, St. Louis, MO
	Raf Kinase Inhibitor Protein (RKIP), Lympho-Vascular Invasion and Peritoneal Invasion Can Be Used To Identify a High-Risk Group of Stage II Colorectal Cancer Patients Brendan Doyle, Suzanne Hagan, Fahd Al-Mulla, Lucy Scott, Sharon Harden, Jim Paul, Hugh Mulcahy, Graeme I Murray, Kieran Sheahan, Jacintha O'Sullivan, Walter Kolch , Trinity College, Dublin, Ireland: Glasgow Caledonian University, Glasgow, United Kingdom; Kuwait University, Kuwait, Kuwait; University of Glasgow, Glasgow, United Kingdom; Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom; St. Vincent's University Hospital, Dublin, Ireland; University of Aberdeen, Aberdeen, United Kingdom; University College Dublin, Dublin, Ireland
	Differences in TMPRSS2-ERG Gene Fusion, PTEN Deletion, and SPINK1 Overexpression in Prostate Cancer in African-American and Caucasian Men Francesca Khani, Juan Miguel Mosquera, Kyung Park, Abhishek Srivastava, Ashutosh K Tewari, Mark A Rubin, Brian D Robinson , Weill Cornell Medical college, NY
	Identification of a Novel Prognostic microRNA Signature in Mantle Cell Lymphoma Rashmi S Goswami, Eshetu G Atenafu, Levi Waldron, Yali Xuan, Wei Xu, Patricia P Reis, John Kuruvilla, David J Good, Denis J Bailey, Raymond Lai, Alanna Church, Wilson S Lam, David P LeBrun, Laurie H Sehn, Pedro Farinha, Randy D Gascoyne, Michael R Crump, Igor Jurisica, Suzanne Kamel-Reid , University Health Network, Toronto, Canada; Harvard School of Public Health, Boston, MA; Universidade Estadual Paulista Julio de Mesquita Filho, Botucatu, SP, Brazil, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; Cross Cancer Institute, Edmonton, AB, Canada; Queen's University, Kingston, ON, Canada; British Columbia Cancer Agency, Vancouver, BC, Canada; Ontario Cancer Institute, Toronto, ON, Canada

Does Genotyping for Warfarin Sensitivity Save Lives? A Study of Individuals on Warfarin Who Died of Bleeding Charlene Hellman, Clarissa Krinsky, Sarah Lathrop, Mohammad A Vasef , University of New Mexico, Albuquerque, NM

Carotid Plaque Inflammation and Morphology Is Associated with Early Stroke Recurrence Susan Prendeville, Michael Marnane, Aine Merwick, Orla Sheehan, Niamh Hannon, Tim Grant, Peter Kelly, Niall Mulligan , Master Misericordiae University Hospital, Dublin, Ireland; University College Dublin, Dublin, Ireland

1. "A Practical Guide to Molecular Testing in Cancer" (headed by Dr. Julia Bridge (Univ. Nebraska) was "sold out" attracting virtually a maximum room number of 495 registrants on Monday. This course has a CD in addition to the extensive syllabus.


2. Advanced Molecular Pathology course (headed by Dr. Frederic Barr, Univ. of Pennsylvania) on Tuesday attracted 252 registrants and included a CD in addition to the extensive syllabus (the third highest in history).


3. A course in its third year entitled "Careers in Investigative Pathology" directed by Drs. Massimo Loda (Brigham & Women's/Dana Farber) and David Berman (Johns Hopkins) was entitled "Get Published". This course attracted 107 attendees.


4. In addition Dr. Sharon Weiss (Emory University) gave a course entitled "Navigating the Academic Waters: A Survival Course for Residents/Junior Faculty". It also was "sold out "with 104 attendees.


5. Another Special Courses was Dr. Tarik Elsheikh's (Cleveland Clinic) day -long Basic Principles of Cytology which had 346 registrants.


6. Finally, Dr. Jennifer Hunt's (Univ. Arkansas) new course entitled Introduction to Molecular Pathology for the Practicing Pathologist which had 264 registrants.

Thus the three Molecular Courses had over 1,000 attending pathologists.

Twentysix Companion Societies presented their educational endeavors on Saturday night and Sunday. This year we have two new added USCAP Companion Societies: Association for Pathology Informatics (API) and the Association of Veterinary Pathology. The total number of registrants (registrants x courses) was 6737, by far and away the highest in our history (67% of all attendees attended at least one Companion Society Symposium). This year was our seventh year for the Companions and the Specialties to go "paperless". All of the Companion Society handouts were placed on the USCAP website at least two weeks before the meeting.

The Nathan Kaufman Timely Topic Lecture, entitled, "The Cancer Genome: A Step Towards Personalized Therapy" was given by Dr. Bogdan Czerniak from M. D. Anderson. It was very well received by the appreciative audience of over 2200 pathologists.

Dr. Robert Kurman (Johns Hopkins) gave the fifty-fourth Maude Abbot Lecture entitled: "Ovarian Carcinogenesis. Myths, Models, and Paradigms. Observations of a Biology Watcher. " This elegant, enthusiastic, and sometimes funny lecture was also attended by over 2200 pathologists. His was truly an outstanding presentation that was enjoyed by all present.

The Distinguished Pathologists Award was presented this year to an individual in recognition of his long-term, distinguished service in the development of the discipline of pathology and the USCAP: Dr. Stephen G. Silverberg (Univ. Maryland), recognized by the Academy membership for his major and extensive contributions to pathology over the years.

The President's Award was presented this year to Dr. Robin Cooke (retired, Royal Brisbane Hospital).. Robin is best known to our membership as the man behind the camera. Many of the photographs that have appeared on Academy publications and its website over the years are Robin's unique contributions to the successes of the Academy. Please see the USCAP website of the 2012 Annual Meeting for details about this outstanding and dedicated individual.

The F.K. Mostofi Distinguished Service Award went to Dr. Celeste Powers (Medical College of Virginia) for her major work in molecular mechanisms of oncogenesis in gastrointestinal stromal tumors (GIST), and molecular characterization of novel fusion genes, which may serve as specific molecular markers in diagnosis and prognosis of soft tissue and bone tumors, as well as potential therapeutic targets.

The Ramzi Cotran Young Investigator Award was presented to Dr. Cristina Antonescu (New York Hospital - Weill Cornell School of Medicine) for her major work in molecular mechanisms of oncogenesis in gastrointestinal stromal tumors (GIST), and molecular characterization of novel fusion genes, which may serve as specific molecular markers in diagnosis and prognosis of soft tissue and bone tumors, as well as potential therapeutic targets.

The Benjamin Castleman Award (for the most outstanding paper in the field of human pathology) was awarded to Dr. Daniel Winer (University Health Network, Toronto) for his paper entitled "B Cells Promote Insulin Resistance Through Modulation of T-Cells and Production of Pathogenic IgG Antibodies", published in Nature Medicine 17(5): 610-617, May 2011. The Award was presented by Dr. Greg Lauwers, Vice-Chair of Pathology at Massachusetts General Hospital in Boston.

The F. Stephen Vogel Award (for the most outstanding paper published in an Academy journal by a pathologist-in-training) went to Dr. Elizabeth Demicco (MD Anderson) for her paper entitled, "The dichotomy in carcinogenesis of the distal esophagus and esophagogastric junction: intestinal-type vs cardiac-type mucosa associated adenocarcinoma" published in Modern Pathology (2011- vol: 24, pp 1177-1190).

The USCAP, in conjunction with Beth Israel Deaconess Hospital/Harvard, presented the Harvey Goldman Master Teacher Award to Dr. Virginia LiVolsi (Univ. Pennsylvania).

The 19 evening Specialty Conferences, which are organ-based, were held from 7:30-9:30 PM, a testimony to the continuing endurance of the meeting's registrants. All of the evening Specialty Conferences are online on the Academy's website. SAMs are offered for participation in these conferences.

Other educational endeavors by the USCAP these past few years include:

1. Development and launch of MyPath. The Innovative Educational Products Committee, formed in response to the Long Term Strategic Planning Initiative of the USCAP, launched MyPath to great interest and excitement during the Annual Meeting. Over 1,000 attendees logged on to the site during the Annual Meeting and began to explore its possibilities. This product is a web portal designed to place at the desktop of the diagnostic pathologist a single source for acquiring high quality, curated medical content to be used in the practice of pathology. The website allows access to most USCAP meeting materials (including synchronized presentations with Power Point slides and audio components), the last ten year's worth of articles published in Modern Pathology and Laboratory Investigation, a completely searchable on-line version of Rosai's Surgical Pathology and an ever expanding menu of products. Further, MyPath offers a networking feature that enables users to discuss and evaluate content of articles with other similarly interested users. Versions 1.01 and 1.1 are already well into the planning stage, each with a wealth of new information and more exciting user options.


2. The First and Largest American Board of Pathology-approved "Self Assessment Modules" (SAM): As of this Annual Meeting, every single short course and long course offered SAMs credit. Most of the Specialty Conferences, Special Courses and Companion Society Meetings also offered them. According to the ABP, the USCAP has more SAMS than any other pathology society (one for every day of the year: over 360).


3. The continued growth and diversification of the eAcademy. This online long distance-learning tool renders CME and/or SAM credit for a minor charge. This is under the Direction of Dr. Jeffrey Prichard (Geisinger). The APECs cases (anatomic pathology cases) were the initial venture into web-based educational offering and there are presently over four dozen interactive, dynamic cases of all types available. It is now possible to enroll in expired Short Courses and Special Courses and receive CME/SAMs credits for them purely as an on-line educational opportunity. Many new opportunities are currently in the works.


4. Continuing involvement in altruistic activities, including West and Eastern Sub-Saharan Africa. The "Friends of Africa" program raised $112,000 to support the travel of sub-Saharan African pathologists to the International Academy of Pathology congress to be held in Cape Town later this year.


5. Continuing growth of the free USCAP "Knowledge Hub/Pathology Portal".


6. Over 500 Virtual Slides are now up on the USCAP website for free (e.g., IAP Centennial; annual evening Specialty Conferences.)


7. The development of the Complete Itinerary Planner (electronic planner) for the Annual Meeting is now through several permutations and continues to improve with each refinement.


8. Online Membership Renewal and Registration and Evaluations for all of the Academy's courses.


9. A Poster Creation Service and ability to demonstrate entire abstract online.

EXHIBITORS: In addition to the high number of attendees, we also reached record-breaking numbers in our Exhibit Hall. With 130 exhibitors, this proved to be our largest Exhibit Show in history. There were a total of 279 booths available for visitation. In fact since 2004 with its 129 booths, we have more than doubled the exhibit booths! In recent years, the Academy has twice won Tradeshow Week's Award for the "Fastest 50 Growing Shows". With our 102nd meeting in 2013 we anticipate this number will continue to increase.

In recent years, the Academy has rolled out a number of new initiatives for our Junior members including:

• Saturday Leadership Seminar for residents conducted by Dr. Carol Farver (Cleveland Clinic) that was fully subscribed and a huge success. This was the first year of this program and given the initial success, will be augmented at future meetings.


• A cocktail reception for residents, members of the USCAP Council and Ambassadors designed for our future leaders to meet our present ones.


• Fellowship Fair with 40-55 institutions to discuss hundreds of fellowships (this year 45).


• The evening Specialty Conference just for house staff/fellows.


• The House Staff Hospitality Lounge where Academy and Pathology leaders from throughout North America gathered to talk with the house staff.


• In addition the Weiss and Loda/Berman courses listed above are aimed to these young pathologists.

There are several changes to our USCAP Committees:

• Four new members of the Education Committee (under the Direction of Dr. John Goldblum) are: Edi Brogi, Laura Collins, Megan Lim and Adeboye Osunkoya.


• Dr. Jeff Myers (University of Michigan),is by vote of the membership the new President-Elect of the Academy, and Dr. Celeste Powers (Medical College of Virginia) is the Vice President. . The newly elected (by the Academy membership) Council members are: Drs. Wendy Frankel, Jennifer Hunt and John Sinard.


• The Finance Committee is headed by Dr. Jim Linder (University of Nebraska) who replaces Dr. Peter Banks and our newest member is Dr. Julia Dahl. The Publications Committee is nowchaired by Dr. Murray Resnick, who replaces Dr. Ronald DeLellis. The newest members of the Ramzi Cotran Young Investigator Committee are Drs. Kathleen Cho and Laura Lamps. New Members of the Castleman Award Committee include: Drs Jennifer Hunt, Cristina Antonescu, and Matt van de Rijn. The newest members of the Vogel Award Committee are Drs. Alexander Lazar (Chair) and Cynthia Guy. Dr. Bruce Smoller is our newest Alternate Delegate to the AMA and will join Dr. Jack Strong who remains as our Delegate. Drs. Allan Tucker and Nicole Riddle will serve as members of the Pathology Section Council at the AMA House of Delegates. The newest member (at large) of our USCAP Nominating Co is Julia Bridge. All of the members of the various USCAP Committees are noted on our website.

Next years large Annual USCAP meeting will be in Baltimore, Maryland, from March 2-8, 2013.

Thanks for all your support for all those we serve--our patients, our physicians and our students.

Bruce R. Smoller, Secretary-Treasurer and Executive Vice President, USCAP