2013 Annual Meeting

— SPECIALTY CONFERENCE HANDOUT —

Head & Neck/Endocrine Pathology

Thursday, March 7, 2013, 7:30 PM
CC 309

Click the button above to add this event to your Itinerary Planner...

Challenging Diagnoses in Head and Neck, and Endocrine Pathology

Moderator:
BRUCE WENIG
Beth Israel Medical Center
New York, NY
Disclosure:
In accordance with ACCME guidelines regarding disclosure, the USCAP policy requires that faculty members who have a significant financial or other relationship with a commercial company, entity, or service (which will be discussed in this Symposium) must disclose this to attendees. The Academy also requires that speakers disclose any products that are not labeled for the use under discussion. The speakers listed below have indicated they have nothing to disclose.
Panelists:
William C. Faquin, Massachusetts General Hospital, Boston, MA
Edward B. Stelow, University of Virginia Health System, Charlottesville, VA
Virginia A. LiVolsi, University of Pennsylvania, Philadelphia, PA
William H. Westra, The Johns Hopkins Hospital, Boston, MA

Clinical histories are displayed below. For the fastest viewing of virtual slides, click:

under each thumbnail image below. You must have Aperio ImageScope installed on your PC.

Get ImageScopeIf you do not already have Aperio ImageScope, Windows users with administrator privileges may download and install a free version in order to view USCAP Virtual Slides. Click the icon on the right to get your free copy:

Or, click on slide thumbnail images to view each slide
in a Web-based slide viewer, which is somewhat slower.

If you have any difficulties viewing these slides, email or call George Clay at +1.724.449.1137.

Case 1 - Click here for Text and References

Submitted by: William C. Faquin

Clinical Summary:

A 55 year-old man presented to the ENT clinic with a one- year history of an enlarging, painless preuaricular mass. A CT scan revealed a 3.5 cm mass limited to the anterior superficial lobe of the left parotid gland. Clinical exam revealed no lymphadenopathy and an intact facial nerve function. The patient was referred to the FNA clinic where an FNA of the mass was performed.

Case 2 - Click here for Text and References

Submitted by: Edward B. Stelow

Clinical Summary:

49 YO Woman with a Right-Sided Sinonasal mass

Case 3 - Click here for Text and References

Submitted by: Virginia A. LiVolsi

Clinical Summary:

This 65 year old man presented with recurrent hyperparathyroidism. He had had a parathyroid “adenoma” removed in 1985 and was subsequently well. In 2012 hypercalcemia was noted. He had no symptoms although he was a poor historian and was mentally challenged. At exploration a 14 gram mass was removed from the left upper neck. Additional parathyroid was removed and a portion of the large gland was implanted in his left arm. Postoperatively his calcium and PTH levels normalized. The patient has several first degree relatives with parathyroid and pancreatic tumors. Clinically the family is diagnosed with MEN I (Wermer syndrome).

Pertinent Laboratory Data:

Serum calcium range about 13 mg/dl; PTH over 1000 units.

Case 4 - Click here for Text and References

Submitted by: William H. Westra

Clinical Summary:

50 year-old woman presenting with nasal obstruction and nasal bleeding

Pertinent Laboratory Data:

Imaging studies show a 7 cm mass centered in the right nasal passage with extension into the left nasal passage, nasopharynx, and right ethmoid and maxillary sinuses (Figure 1).

Case 4 - Figure 1
histopathologic findings
Case 4 - Figure 2
histopathologic findings
Case 4 - Figure 3
histopathologic findings
Case 4 - Figure 4
histopathologic findings
Case 4 - Figure 5
histopathologic findings
Case 4 - Figure 6
histopathologic findings; immunohistochemical stains for cKit (middle panel) and p63 (lower panel)
Case 4 - Figure 7
p16 immunohistochemical stain
Case 4 - Figure 8
Handouts for all Specialty Conferences will be accessible via the "Educational Materials" section on the homepage the morning after each respective conference. Printed copies of the handout will not be available at the meeting.