Neoplasms, primary or metastatic, can present clinically as diffuse non-neoplastic lung disease and be difficult to recognize histologically. Additionally, neoplasms may arise in the setting of non-neoplastic disease and the clinical implications of such findings are not well known to clinicians and pathologists. Using a practical case presentation approach, this short course will focus on examples of neoplastic disease presenting as diffuse lung disease, and neoplasms complicating non-neoplastic disease. Recent advances in pathogenesis, ancillary testing, patient management and prognosis as well as potential pitfalls and differential diagnosis will be discussed for each case.

The course is designed for residents and fellows as well as pathologists who encounter surgical lung biopsies in their practice. Upon completion of this educational activity, participants should be able to: 1) Explain about tumor types which can mimic or complicate non-neoplastic lung disease; 2) Recognize the histologic features of tumors which can mimic or complicate non-neoplastic lung disease; 3) Discuss the differential diagnosis of these tumors and non-neoplastic lung diseases; and 4) Describe their clinical significance and prognosis.

Pre-registrants will be able to view case histories and virtual slide of the study cases, prior to the meeting on the USCAP website. A comprehensive syllabus will be distributed at the course. After the meeting, all course registrants will have access to the PowerPoint presented at the Annual Meeting along with the text portion of the syllabus on the USCAP website.

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