POSTER SESSION II Monday, March 24, 2003   —  1:00 - 4:30 PM Exhibit Hall A - C PULMONARY PATHOLOGY 176 Expression of CD117 (c-kit) in Non-Small Cell Lung Cancer Is Not Associated with Neuroendocrine Differentiation (1439) WZ Tang, P Zhang, West Virginia University, Morgantown, WV 177 CD117 (+) Small Cell Lung Cancer (SCLC) Lacks the Asp8166Val Point Mutation in Exon 17 (1423) WD Mojica, P Starostik, RT Cheney Roswell Park Cancer Institute & Kaleida Health System, Buffalo, NY 178 Prognostic Implications of Neuroendocrine Differentiation and Hormone Production in Stage I Non-Small Cell Lung Cancer (1426) G Pelosi, A Iannucci, A Sonzogni, F Maffini, P Maisonneuve, F Pasini, A Terzi, G De Manzoni, G Viale European Institute of Oncology, Milan, Italy; City Hospital, Verona, Italy; University of Verona, Verona, Italy 179 HER-2/neu Gene Amplification in Neuroendocrine Tumors and Non-Small Cell Carcinomas of the Lung (1427) G Pelosi, B Del Curto, P Dell'Orto, F Pasini, U Pastorino, A Iannucci, F Maffini, G Viale European Institute of Oncology, Milan, Italy; University of Verona, Verona, Italy; City Hospital, Verona, Italy 180 p63 Expression Is Detected in Both Small Cell and Non-Small Cell Lung Carcinoma (1393) NHC Au, M Cheang, E Yorida, A Coldman, L Grimes, J Flint, J English, M Elliott, B Gilks Vancouver General Hospital and University of British Columbia, Vancouver, BC, Canada; University of Louisville, Louisville, KY; British Columbia Cancer Agency; St Pauls Hospital and University of British Columbia, Vancouver, BC, Canada 181 Growth Factor Independence 1 (GFI1) Is Associated with Pulmonary Neuroendocrine Tumors (1394) NHC Au, M Cheang, E Yorida, A Karzanjian, C Tan, J English, J Flint, L Grimes, B Gilks Vancouver General Hospital and University of British Columbia, Vancouver, BC, Canada; University of Louisville, Louisville, KY; University of British Columbia; B.C. Cancer Agency, Vancouver, BC, Canada 182 Cyclin E Expression Correlates with Poor Survival in Atypical Carcinoid (AC) and Large Cell Neuroendocrine Carcinoma (LCNEC) (1433) E Selbs, E Brambilla, W-S Chu, S Lantuejoul, SL Abbondanzo, N Azumi, PS Hasleton, WD Travis Armed Forces Institute of Pathology, Washington, DC; CHU A.Michallon and INSERM 9924, Grenoble, France; Georgetown University, Washington, DC; University of Manchester School of Medicine, Manchester, United Kingdom 183 Typical and Atypical Pulmonary Carcinoids: Fascin, an Actin-Bundling Protein Associated with Cell Motility, Is an Independent Predictor of Lymph Node Metastases, Correlating with a Deregulated Expression of E-Cadherin and CD99 (1425) G Pelosi, F Pasini, A Iannucci, U Pastorino, P Maisonneuve, A Sonzogni, F Maffini, G Viale European Institute of Pathology, Milan; Verona University; City Hospital, Verona; European Institute of Oncology, Milan, Italy 184 Neuroendocrine Proliferation and Carcinoid Tumors Associated with Necrotizing Granulomatous Inflammation in the Lung (1421) NP Memoli, AE Brown, MF Zakowski, DS Klimstra Memorial Sloan-Kettering Cancer Center, New York, NY 185 TTF-1 Expression in Tumorlets, Typical and Atypical Carcinoids, and Large Cell Neuroendocrine Carcinomas (1398) E Du, P Goldstraw, J Zacharias, O Tiffet, P Craig, A Nicholson, ES Yi University of California San Diego Medical Center, San Diego, CA; Royal Brompton Hospital, London, United Kingdom 186 Co-Expression of Achaete-Scute Homolog-1 (ASH1) with Calcitonin-Gene Related Peptide (CGRP) and Epithelial Cell Markers during NNK-Induced Pulmonary Carcinogenesis in Hamsters (1424) X Naizhen, H Witschi, I Linnoila National Cancer Institute, NIH, Rockville, MD; University of California, Davis, CA 187 Immunohistochemical (IH) Characterization of Primary Lung Adenocarcinoma (ACa) (1412) HS Kim, EK Hong, SY Park, S Lee, HJ Song, JY Ro National Cancer Center, Goyang, Republic of Korea; Asan Medical Center, Seoul, Republic of Korea 188 LKB1 Protein Expression in the Evolution of Glandular Neoplasia of the Lung (1403) H Ghaffar, F Sahin, M Sanchez-Cepedes, GH Su, D Sidransky, WH Westra The Johns Hopkins Medical Institutions, Baltimore, MD 189 Telomerase Expression in Preinvasive Bronchial Lesions (1414) S Lantuejoul, J-C Soria, L Morat, P-Y Brichon, C Brambilla, E Brambilla CHU Albert Michallon, Grenoble; CEA, Fontenay-Aux-Roses; INSERM 9924, Grenoble, France 190 Prognostic Significance of Thyroid Transcription Factor-1 (TTF-1) Expression in Both Conventional (CA) and Bronchioloalveolar Carcinoma (BAC) of the Lung (1435) JF Silverman, RS Saad, H Han, RJ Landreneau, TS Santucci, MY Tung, YL Liu Allegheny General Hospital, Pittsburgh, PA 191 A High-Density Tissue Microarray(TMA) and Immunohistochemistry(IHC) Study of Thyroid Transcription Factor-1(TTF-1) Expression in Non-Small-Cell Lung Cancer(NSCLC) (1438) D-F Tan, Q Li, G Deeb, HK Slocum, N Ramnath, G Loewen, S Wiseman, JJ Brooks Roswell Park Cancer Institute, Buffalo, NY; Univ. of Pennsylvania, Philadelphia, PA 192 Loss of FHIT Protein Expression Is Related to High Proliferation, Low Apoptosis and Worst Prognosis in Non-Small Cell Lung Carcinoma (1440) G Toledo, JJ Sola, E Soria, MD Lozano, A Martinez-Penuela, J Pardo Clinica Universitaria, Pamplona, Navarra, Spain 193 Association of PGP9.5 Staining with Cyclin E, Cdk2, Histone Remodeling Proteins in Non-Small Cell Lung Cancer: Tissue Microarray Assessment (1401) J Fukuoka, T Fujii, T Dracheva, WD Travis, J Jen National Cancer Institute, Bethesda, MD; Armed Forces Institute of Pathology, Washington, DC 194 Expression of Cathepsin H in Lung Tumors (1418) A Loya, A Bazooband, M Menes, MJ Murnane, S Shuja University of Florida Health Science Center, Jacksonville, FL; Boston University School of Medicine, Boston, MA 195 Experimental and Morphological Evidence Reveals That Osteonectin Expression Is Common in Lung Cancer and May Be Related to Tissue Remodeling (1416) F Lonardo, F Siddiq, F Sarkar, A Wali, H Pass Harper University Hospital; Wayne State University School of Medicine; Karmanos Cancer Institute, Detroit, MI 196 Chemotherapy Effect on Non-Small Cell Carcinoma of the Lung: A Light Microscopic Study (1395) CL Aubertine, DB Flieder NYPH-Cornell, New York, NY