POSTER SESSION IV Tuesday, March 25, 2003   —  1:00 - 4:30 PM Exhibit Hall A - C GASTROINTESTINAL PATHOLOGY 73 Genetic Alterations in Gastric Adenomas of Intestinal and Foveolar Phenotypes (617) T-T Wu, SJ Park, J-H Lee, L Mugartegui, SC Abraham University of Texas M.D. Anderson Cancer Center, Houston, TX; Mayo Clinic, Rochester, MN 74 Expression of Telomerase Activity, Human Telomerase RNA and Telomerase Reverse Transcriptase in Gastric Adenocarcinomas (624) J Yoo, H-J Choi, S-J Kang, B-K Kim, C-S Kang St.Vincent's Hospital Catholic University, Suwon, Kyung-Ki Do, Korea 75 CpG Island Hypermethylation in Gastric Carcinomas with High Microsatellite Instability (563) SE Kim, H Kim, HS Shim, H Kim Yonsei University College of Medicine, Seoul, Korea 76 Aberrant Promoter Methylation Profile in Premalignant Lesions and T1 Adenocarcinoma of the Stomach (570) J-H Lee, S-J Park, J-S Seo, J-H Nam, C Choi, S-W Jung, A Rashid, SR Hamilton, T-T Wu MD Anderson Cancer Center, Houston, TX; Chonnam National University Medical School; Genome Research Center for Hematopoietic Diseases, Kwangju, Kwangju, Republic of Korea 77 HER2 Gene Amplification and Protein Overexpression in Gastric Adenocarcinoma (612) H Wang, J Hurley, M Jorda, C Gomez-Fernandez University of Miami/Jackson Memorial Medical Center, Miami, FL 78 E-Cadherin Expression in Sporadic Gastric Cancer from Mexico. Exon 8 and 9 Mutations Detected by Mutation-Specific Antibodies Are an Infrequent Event Associated with Poor Survival (537) A Gamboa-Dominguez, C Dominguez-Fonseca, L Quintanilla-Martinez, R Vargas, E Reyes-Gutierrez, B Luber, KF Becker, I Becker, H Hoefler, F Fend Instituto Nacional de Ciencias Medicas SZ, Mexico, D. F., Mexico; GSF-Research Center for Environment and Health, Neuherberg; Technical University Munich, Munich, Germany 79 Trefoil Factor 3 May Contribute to Gastric Carcinogenesis through Up-Regulating Cyclooxygenase-2 Protein Expression (520) Y Chen, X Tan, MS Rao The Feinberg School of Medicine, Northwestern University, Chicago, IL 80 CD44v6-Expression: A Late Stage Phenomenon in the Intestinal Metaplasia-Carcinoma Sequence of the Stomach? (542) C Gulmann, A Grace, M Leader, S Patchett, D Butler, E Kay Royal College of Surgeons in Ireland, Dublin, Ireland 81 Endoscopic Mucosal Resection for Gastric Epithelial Neoplasm. A Study of 39 Cases with Analysis of Pathologic Features (567) GY Lauwers, S Ban, M Mino, S Ota, T Matsumoto, S Arai, WR Brugge, M Shimizu Massachusetts General Hospital, Boston, MA; Saitama Medical School, Saitama, Japan; Kyushu University, Fukuoka, Japan 82 Detection of mRNA of Carcinoembryogenic Antigen(CEA) Provide More Significant Prognostic Value in Peritoneal Washes Than in Bone Marrow and Peripheral Blood for Patients with Gastric Cancer (517) HK Chang, CH Chjeon, KH Park Medical College of Kosin University, Pusan, Pusan, Korea; Medical College of Taegue-Catolic University2, Taegu, KyungsangPukDo, Korea 83 Chromogenic In Situ Hybridization (CISH) of Chromosome 7 Supports Lack of Association between Colonic Lesions and the Birt-Hogg-Dubey Syndrome (509) A Auerbach, R Ronchetti, WM Linehan, MJ Merino National Cancer Institute, Bethesda, MD 84 Mixed Hyperplastic/Adenomatous Colorectal Polyps: A Multi-Institutional Incidence Study (513) KP Batts, LJ Burgart, JR Goldblum, JK Greenson, M Haber, D Jain, L Lamps, DN Lewin, GY Lauwers, E Montgomery, K Washington Abbott NW Hospital, Minneapolis, MN 85 Serrated Adenomas and Villous Tumors of the Colorectum: Their Common Phenotypic Features (511) S Ban, N Mitsuki, T Mitsuhashi, Y Shimizu, T Hirose, M Shimizu Saitama Medical School, Saitama, Japan 86 hMLH1 Expression in Hyperplastic Polyps of the Proximal Colon (593) CA Paulsen, ML Slattery, WS Samowitz University of Utah Health Sciences Center, Salt Lake City, UT 87 Absence of the Physiologic Cellular Kinetic Balance and Down-Regulation of mlh1/msh2 Characterize Deep Topographic Compartments of Colo-Rectal Adenocarcinomas (516) A Blanes, JJ Jimenez-Martin, MT Miranda, SJ Diaz-Cano University of Malaga School of Medicine, Malaga, Spain; Barts and the London School of Medicine, London, United Kingdom 88 Aberrant CpG Island Hypermethylation in Colorectal Cancer and Preneoplastic Lesion (572) S Lee, JS Kim, JY Ro, GH Kang National Cancer Center, Ilsan, Korea; Asan Medical Center, Seoul, Korea; Seoul National University College of Medicine, Seoul, Korea 89 Age-Related Accumulation of Medullary-Type Poorly Differentiated Adenocarcinoma with hMLH1 Promoter Hypermethylation and hMLH1 Aberrant Expression in the Large Intestine (508) T Arai, Y Esaki, M Sawabe, I Kasahara, N Honma, K Takubo Tokyo Metropolitan Geriatric Medical Center and Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan 90 Cancer Family History in Colorectal Carcinoma (CRC) Patients with Known Microsatellite Instability (MSI) Status, and hMLH1 and hMSH2 Protein Expression (594) A Paya, C Alenda, R Jover, FI Aranda Hospital General Universitario de Alicante, Alicante, Spain 91 Immunohistochemistry for MLH1, MSH2, MSH6, and PMS2 Identifies Most Cases with Germline HNPCC Mutations and Methylation of the MLH1 Promoter (534) WL Frankel, H Hampel, H Nakagawa, C Morrison, A de la Chapelle The Ohio State University Medical Center, Columbus, OH 92 Concordance of Immunohistochemistry among HNPCC Heterodimers MLH1 and PMS2, and MSH2 and MSH6 in Microsatellite Unstable Colorectal and Endometrial Carcinomas (582) H Nakagawa, H Hampel, A de la Chapelle, WL Frankel The Ohio State University Medical Center, Columbus, OH 93 Mucinous Carcinoma of the Colorectum: Correlation between Microsatellite Instability, Clinicopathologic Features and Survival (557) S Kakar, SN Thibodeau, TC Smyrk VA and UCSF Medical Center, San Francisco, CA; Mayo Clinic, Rochester, MN 94 Histopathological Characterization of Familial and Sporadic Colorectal Carcinoma with Microsatellite Instability (MSI) (601) J Shia, N Ellis, PB Paty, GM Garrett, J Qin, X Zhang, K Offit, AJ Markowitz, WL Gerald, DS Klimstra Memorial Sloan-Kettering Cancer Center, New York, NY 95 Thymidylate Synthase Expression Correlates with Survival in Colorectal Carcinomas: A Preliminary Study (524) M Cuatrecasas, E Dotor, L Pareja, M Navarro, V Moreno, C Murcia, G Capella Hospital St.Jaume, Calella; Catalan Institute of Oncology, ICO, Barcelona, Spain