This course is designed as a case-based review of infections which are primary to the lung. The discussion will review the patterns of injury for each infectious agent, including the most common histopathology as well as more unusual pathologic features, including pathologic features of new clinical entities. In addition, the most current diagnostic tools including histochemical and immunohistochemical studies will be discussed with an analysis of the sensitivity and specificity of each test. Finally, the role of molecular techniques in the diagnosis of pulmonary infections, especially viral and mycobacterial, will be reviewed. This course is intended for general surgical pathologists who will find a review of the histopathology and diagnostic work-up of pulmonary infections useful and for pulmonary pathologists who wish an update on newer diagnostic techniques and the histopathologic features of new etiologic agents. A limited number of loan sets of glass slides will be available for advance mailing. All registrants will be mailed a set of transparencies after the meeting. A detailed syllabus will be distributed at the course.