submitted by:
David Klimstra
Memorial Sloan Kettering Cancer Center
New York, New York
The patient is a 67 year old female who presented with pneumonia, with only partial resolution following
antibiotic treatment. A chest CT scan disclosed a 1.2 cm right lower lobe nodule that was circumscribed
and non-calcified. Review of old chest radiographs showed the nodule, which had been stable over at
least 6 years. A fine needle aspiration was performed and interpreted as positive for carcinoid tumor.
A right lower lobectomy and mediastinal lymph node dissection were performed. Grossly, there was a 1.5
cm red to tan, slightly indurated spherical mass situated 1.4 cm deep to the pleural surface.
submitted by:
Claudia Y. Castro
University of Alabama
Birmingham, Alabama
The patient is a 49 year-old Hispanic male who complained of cough for 2 months. His past medical
history was significant only for heavy smoking (2 pack of cigarettes /day/ 15 years) . A chest radiograph
showed a well-circumscribed nodule in the periphery of the right upper lobe. Patient underwent wedge
resection. After frozen section diagnosis, a completion of the lobectomy was performed. The specimen
consisted of a wedge biopsy of lung (4.8 x 2.3 x 2.2 cms) containing a relative well circumscribed, 1.4
cms subpleural nodule. The cut surface was white, firm and focally necrotic. The nodule was located at
1.0 cms from the staple surgical resection margin.
submitted by:
Cheryl M. Coffin
University of Utah
Salt Lake City, Utah
A six-year-old girl had a right lower lobe lung mass. Wedge resection revealed a 2.6x2.5x1.5 cm firm
nodule with a grey-white whorled surface.
submitted by:
Jae Y. Ro
Ulsan University College of Medicine
Seoul, Korea
A 70-year-old man who had a history of stroke took a CT scan of the chest demonstrating a 3.0 cm mass in
the left lower lobe. A needle biopsy revealed an adenocarcinoma. He had a past history of hypertension,
but there was no history of tuberculosis. He was a non-smoker. There was no remarkable family history.
His general conditions were good and laboratory findings were within normal limits. Staging procedures
including bone scan and MRI of the brain did not reveal metastasis. Left lower lobe lobectomy was
performed 1 month after the histologic diagnosis of carcinoma.
submitted by:
Michael Koss
Keck School of Medicine at USC
Los Angeles, California
The patient is a 63 year-old woman with coronary artery disease who developed a progressive neurologic
illness that resembled spinocerebellar ataxia. As her physician thought her neurologic illness may have
been a manifestation of a paraneoplastic syndrome, she underwent chest and upper abdomen computed
tomography (CT) looking for a primary lung malignancy. The chest CT showed a 2.0-cm in diameter nodule
in the left lung apex. Contrast studies suggested it was likely malignant and she had the nodule
resected. Sections are from this nodule.
