Papillary Tumors with Psammoma Bodies
Carmen Tornos Memorial Sloan Kettering Cancer Center New York, NY
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Clinical History
38 year old woman with a 2- 3 cm palpable mass in the right axilla. Her breast was normal on mammography, MRI and ultrasound. The mammogram showed a calcified mass in the axilla. The mass was excised.
Case 3 - Figure 1 - Metastatic low grade ovarian serous carcinoma to an axillary lymph node
Case 3 - Figure 2 - The tumor is predominantly papillary and it is associated with psammoma bodies.
Case 3 - Figure 3 - The lymph node has some benign-appearing cystic inclusions similar to "endosalpingiosis".
Case 3 - Figure 4 - Another area of the metastasis showing the papillary architecture and associated psammoma bodies.
Case 3 - Figure 5 - The metastasis has areas of invasion with desmoplastic stromal reaction, and invasion in the form of small papillae surrounded by a clear space or cleft.
Case 3 - Figure 6 - The tumor is papillary, it has uniform bland nuclei, and it is associated with psammomatous calcifications.
Case 3 - Figure 7 - Invasion in the form of small papillae surrounded by a clear space or cleft (so called "micropapillary type of invasion").
Case 3 - Figure 8 - High power showing rather uniform and bland nuclei, with finely distributed chromatin, inconspicuous nucleoli, and absence of mitotic activity.
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