Cellular transplantation is emerging as a potential mechanism with which to augment myocyte number in diseased hearts. To date a
number of cell types have been shown to successfully engraft into the myocardium, including fetal, neonatal, and embryonic stem
cell-derived cardiomyocytes, skeletal myoblasts, and stem cells with apparent cardiomyogenic potential. Here we provide a review of
studies wherein myocytes or stem cells with myogenic potential have been transplanted into the heart. In addition, issues pertaining to the
tracking and functional consequences of cell transplantation are discussed.
Myocyte and Myogenic Stem Cell Transplantation in the Heart
Joshua D. Dowell, Michael Rubart, Kishore B.S. Pasumarthi, Mark H. Soonpaa, Loren J. Field
Cardiovascular Research • Volume 58 • Pages 336–350 • 2003