POSTER SESSION II Monday, March 8, 2004   —  1:00 - 4:30 PM Exhibit Hall B and C GENITOURINARY PATHOLOGY 70 AQUA and AMACR: A Novel Paradigm for Automated and Continuous Prostate Cancer Biomarker Measurements (731) MA Rubin, MP Zerkowski, RL Camp, R Kuefer, M Hofer, AM Chinnaiyan, DL Rimm - Brigham and Women's Hospital/ Harvard Medical School, Boston, MA; Yale University School of Medicine, New Haven, CT; University Hospital Ulm, Ulm, Germany; University of Michigan School of Medicine, Ann Arbor, MI 71 An Analysis of the p63/a-Methylacyl-CoA Racemase Immunohistochemical Cocktail Stain in Prostate Needle Biopsy Specimens and Tissue Microarrays (737) SO Sanderson, TJ Sebo, LM Murphy, R Neumann, J Slezak, JC Cheville - Mayo Clinic, Rochester, MN 72 The Clinical Utility of AMACR (p504s) and Basal Cell Cocktail in the Evaluation of Prostate Needle Biopsies: A Prospective Single Institution Study (656) MS Hirsch, TJ Browne, G Brodsky, WR Welch, MF Loda, MA Rubin - Brigham and Women's Hospital, Boston, MA; Harvard Medical School, Boston, MA 73 Expression of Variants of Alpha Methyl- Acyl-CoA Racemase (AMACR) in Prostatic Carcinomas (PC) Using Tissue Microarrays (743) R Sjuve Scott, DA Troyer, JN Mubiru, AJ Valente, J Furman - The University of Texas. Health Science Center at San Antonio 74 AMACR Expression in Proliferative Inflammatory Atrophy of the Prostate Gland (592) TA Bismar, T Zolotarev, MA Rubin - Brigham and Women's Hospital, Harvard Medical School, Boston, MA 75 P504S,34be12 and CK5 Help To Suggest Prostate Carcinoma in Cases of Atypical Small Acinar Proliferation (ASAP) (566) C Alvarez, I Antón, JA Ortiz-Rey, P San Miguel, B Iglesias - POVISA Medical Center, Vigo, Pontevedra, Spain 76 Cytokeratin Evalutation of Prostatic Ductal Adenocarcinoma. Comparison with Prostatic Acinar and Urothelial Carcinomas (669) C Johnson, L Miller, M Grosman, PD Unger - Mount Sinai School of Medicine, New York, NY 77 a-Methylacyl-CoA Racemase (P504S) Expression in High Grade Prostatic Intraepithelial Neoplasia (773) C-L Wu, XJ Yang, M Tretiakova, BA Woda, RH Young, Z Jiang - Massachusetts General Hospital, Boston, MA; University of Chicago, Chicago, IL; Northwestern University, Chicago, IL; University of Massachusetts, Worcester, MA 78 a-Methylacyl Coa Racemase (AMACR) Immunoreactivity in "Non-Neoplastic" Prostatic Acinar Epithelium in pts with Reactive vs Neoplastic Prostate Tissue (780) J Yu, R Dhir, A Gologan, T McHale, F Monzon, C Cai, S Bastacky - University of Pittsburgh Medical Center, Pittsburgh, PA 79 Utility of a Novel Immunohistochemical (IHC) Panel (PSA, High Molecular Weight Cytokeratin and/or p63) in the Differentiation of Poorly Differentiated Prostate Adenocarcinoma (PCa) from Urothelial Carcinoma (UC) (746) M Snyder, R Mehra, LP Kunju, J Montie, RB Shah - University of Michigan, Ann Arbor, MI 80 Alpha-Methylacyl-Coenzyme A Racemase (AMACR/P504S) and MIB-1 Proliferation Index as Objective Markers of High-Grade Prostatic Intraepithelial Neoplasia (HGPIN) in Needle Biopsy Specimens (655) MC Herrera, JR Srigley, SD Lim, SE Mendrinos, MB Amin - Emory University, Atlanta, GA; Credit Valley Hospital, Mississauga, ON, Canada 81 An Immunohistochemical Study with Triple Antibodies and Two Color Reactions on a Single Slide for the Detection of Small Focal Prostate Carcinoma on Needle Biopsies (668) Z Jiang, BA Woda, K Dresser, C Li - University of Massachusetts Medical School, Worcester, MA 82 Characterization of Small Foci of Atypical Glands in Prostate Needle Biopsies Using Double Immunostaining with Polyclonal a-Methylacyl-CoA Racemase and High Molecular Weight Cytokeratin (571) MW Andres, MA Amin, T Freidman, R Malhotra, AR Prasad - University of Arizona Health Sciences Center, Tucson, AZ; William Beaumont Hospital, Royal Oak, MI 83 Basal Cell Cocktail (34bE12 + p63) Distinguishes Zonal Variation of Basal Cells and Peripheral Zone Intermediate Basal Cell Hyperplasia 640 FU Garcia, SS Selim, RA Leon, NK Popnikolov, MM Haber - Drexel University College of Medicine, Philadelphia, PA 84 Downregulation of CD138 and CD10 in Prostatic Adenocarcinomas (PACs): Utility of CD138 as a Basal Cell Marker in Prostate Tissue (729) JS Ross, CE Sheehan, P Kaur, HAG Fisher, RP Kaufman, Jr, BVS Kallakury - Albany Medical College, Albany, NY; Georgetown University Hospital, Washington, DC 85 p16, p53 and Rb Expression in Superficial Transitional Cell Carcinomas of the Bladder: Improved Prediction of Progression (657) A Hitchings, M Kumar, V Nargund, S Jordan, J Martin, DM Berney - St Bartholomews and the Royal London Hospital School of Medicine, London, United Kingdom 86 B-catenin Expression in Normal/Reactive, High Grade Dysplastic/Carcinoma In Situ (CIS) and Neoplastic Urothelial Lesions (728) R Reyes, EA Turbat-Herrera, ML Jones, W Sun, GA Herrera - LSU Health Sciences Center, Shreveport, LA; University of Texas-MD Anderson Cancer Center, Houston, TX 87 A Population-Based Study of Immunohistochemical Detection of p53 Alteration in Bladder Cancer (677) KT Kelsey, T Hirao, AR Schned, S Hirao, T Devi-Ashok, HH Nelson, A Andrew, MR Karagas - Harvard School of Public Health, Boston, MA; Dartmouth Medical School, Hanover, NH 88 Prognostic Factors in Stage Ta/T1 Bladder Cancer Survival: The Role of G1-S Modulators and Proliferation Index (690) A Lopez-Beltran, RJ Luque - Cordoba University Medical School and Reina Sofia University Hospital, Cordoba, Cordoba, Spain; Health University Complex, Jaen, Jaen, Spain 89 Relationship of p53, Ki-67, bcl-2 and p27Kip1 Expression with Different Grading Systems and Prognosis in Transitional Cell Carcinomas of the Bladder (584) O Basturk, AR Kandiloglu, M Lekili, C Asan - Celal Bayar University, Manisa, Turkey 90 Quantitative GSTP1 Methylation Levels Correlate with Gleason Grade and Tumor Volume in Prostate Needle Biopsies (785) M Zhou, Y Tokumaru, D Sidransky, JI Epstein - The Johns Hopkins Medical Institutions, Baltimore, MD 91 Expression of Syndecan-1/CD138 in Prostatic Adenocarcinoma (PAC) Correlates with Tumor Gleason Score and Pathological Stage (572) S Anwar, RA Ambros, TA Jennings, HT Nazeer, B Mian, JS Ross - Albany Medical College, Albany, NY 92 Prostate Specific Membrane Antigen (PSMA) May Assist in the Diagnosis of Prostate Cancer in Patients with Low Serum Prostate Specific Antigen (PSA) Relative to Clinical Stage (589) AJ Birtle, AA Freeman, MC Parkinson, V Primus, J Wedderburn, JRW Masters, SJ Harland, HA Payne - University College Hospital, London, United Kingdom 93 Forkhead Proteins Are Important in Biology of Human Prostate Cancer (626) S Erdamar, R Li, M Sayeeduddin, P Scardino, A Frolov, T Wheeler, G Ayala - Baylor College of Medicine, Houston, TX; Cerrahpasa College of Medicine, Istanbul, Turkey 94 Definition of the Gene Expression Signatures Characteristic of Prostate Cancer Differentiation 635 B Furusato, S Shaheduzzamn, W Zhang, G Petrovics, V Srikantan, M Vahey, DG McLeod, JW Moul, R Becker, CJ Davis, Jr, S Srivastava, IAM Sesterhenn - Armed Forces Institute of Pathology, Washington, DC; Walter Reed Army Medical Center, Washington, DC; Department of Surgery, USUHS, Bethesda, MD 95 Expression of Polymeric Immunoglobulin Receptor (PIGR) in Neoplastic and Non-Neoplastic Prostate Tissue (580) S Bakdash, S Bastacky, M Acquafondata, M Notaro, A Gologan, C Cai, T McHale, R Dhir - University of Pittsburgh Medical Center, Pittsburgh, PA 96 The Expression of Cables, a Cell Cycle Regulatory Gene, Is Progressively Lost in Human Prostate Cancer as Gleason Score Increases (630) AF Feldman, SD Kirley, LR Zukerberg, WS McDougal, C-L Wu - Massachusetts General Hospital, Boston, MA 97 Role of MMP2, MMP14 and TIMP2 on Prostate Cancer Prognosis (752) B Tetu, D Trudel, Y Fradet, F Harel, F Meyer - CHUQ, Hotel-Dieu de Quebec, Laval University, Quebec City, QC, Canada 98 Direct In Situ Analysis of Telomere Lengths in Primary Prostate Cancer and Prostate Cancer Metastases (701) AK Meeker, JL Beckman-Hicks, CJ Bennett, H Fedor, AM De Marzo - Johns Hopkins University School of Medicine, Baltimore, MD 99 Expression of p27kip1 in Prostate Cancer: Correlation with Histopathological Parameters and Clinical Stage (644) MR Grant, S Bastacky, C Cai, R Dhir - University of Pittsburgh Medical Center, Pittsburgh, PA 100 Outcome-Based Definition of DNA Tetraploid as Determined by Digital Image Analysis (DIA) in Prostate Cancer (Ca) Tissue Sections (722) DM Pierson, TJ Sebo - Mayo Clinic, Rochester, MN 101 Up-Regulation of Soluble ErbB3 in Metastatic Prostate Cancer Cells and Activated Osteoblasts in Bone Marrow (764) F Vakar-Lopez, C-J Cheng, J Kim, GG Shi, JR Tunstead, P Troncoso, A Ruggeri, S-M Tu, S-H Lin - UT M. D. Anderson Cancer Center, Houston, TX 102 Expression of Estrogen a and b , Progesterone, and Androgen Hormone Receptors in the Canine Prostate: Differences between Normal, Inflamed, Hyperplastic and Neoplastic Glands (638) FL Gallardo, T Mogas, T Baro, R Rabanal, J Morote, J Reventos, J Lloreta - Facultat de Veterinaria, Universitat Autonoma de Barcelona; Hospital del Mar, Universitat Pompeu Fabra; Hospital Vall Hebron, Barcelona, Spain 103 Differences in Genetic Profile of Prostatic Carcinoma in African-American Versus Caucasians Using Lase Micro Dissection and Loss of Heterozygosity Analysis (570) A Andea, K Kolizeras, C Butler, X Hong, F Sarkar, W Sakr - Harper University Hospital, Karmanos Cancer Institute & Wayne State University, Detroit, MI 104 Impact of Vitamin D TaqI Receptor Polymorphisms on Prognosis after Prostatectomy among Caucasian and African American Men (680) K Kolizeras, H Williams, W Sakr, IJ Powell, C Butler, SJ Land, JY Zhou, Y Sun, C Wang, NP Patel, L Heilburn, MR Hughes, RB Everson - Harper University Hospital, Karmanos Cancer Institute & Wayne State Unviersity, Detroit, MI 105 Role of Thromboxane Synthase Expression in Prostate Cancer Progression (783) H Zhang, D Nie, X Li, W Sakr, D Grignon, M Che, KV Honn - Harper University Hospital, the Karmanos Cancer Institute and Wayne State University, Detroit, MI