Columbia, Vancouver, BC and Carlos E. Bacchi, M.D., Ph.D., State University of Sao Paulo, Brazil

Immunohistochemistry is a powerful technique that has become an integral and essential tool of the diagnostic surgical pathologist. This course will present the state of the art of diagnostic immunohistochemistry, taking a practical but comprehensive approach utilizing an unknown case format. First there will be an introduction highlighting some methodologic issues and caveats. The major portion of the course will focus on the application of immunohistochemistry to diagnostic problems in surgical pathology, including; (a) characterization of large cell, undifferentiated malignant neoplasms; (b) characterization of small, blue round cell tumors; (c) determination of primary site of carcinomas presenting as metastases; (d) subclassification of soft tissue tumors and sarcomas; (e) analysis of difficult breast lesions using non-prognostic markers, including those identifying myoepithelial cells. A syllabus will be distributed at the course. After the course all registrants will be mailed a CD of material projected at the course.