
/* Sequence of slide descriptions */
desc11  =  'Case 1 - Figure 1 </font><br><font id=normaltext>Skin biopsy shows a dense lymphoid infiltrate extending from the superficial through the deep dermis to the subcutaneous tissue (H&E, original magnification X20)                                                                                                                                                                                                        ';
desc12  =  'Case 1 - Figure 2 </font><br><font id=normaltext>The epidermis has pseudoepitheliomatous hyperplasia (H&E, original magnification X40)                                                                                                                                                                                                                                                                                    ';
desc13  =  'Case 1 - Figure 3 </font><br><font id=normaltext>The epidermis is focally ulcerated (H&E, original magnification X100)                                                                                                                                                                                                                                                                                                    ';
desc14  =  'Case 1 - Figure 4 </font><br><font id=normaltext>The lymphocytes are predominantly large.  Small lymphocytes surround the tumor mass and focally infiltrate the epidermis (H&E, original magnification, X400)                                                                                                                                                                                                             ';
desc15  =  'Case 1 - Figure 5 </font><br><font id=normaltext>The large lymphocytes have dysplastic, large, folded, indented or U-shaped nuclei with dispersed chromatin, prominent nucleoli, and abundant eosinophilic cytoplasm.  Small lymphocytes with somewhat irregular, hyperchromatic nuclei focally infiltrate the epidermis (H&E, original magnification X600)                                                               ';
desc16  =  'Case 1 - Figure 6 </font><br><font id=normaltext>The tumor cells have a sheet-like growth pattern and numerous mitotic figures are present (H&E, original magnification X600)                                                                                                                                                                                                                                             ';
desc17  =  'Case 1 - Figure 7 </font><br><font id=normaltext>The large dysplastic lymphocytes and the small lymphocytes are CD3+ T-cells (Clone PSI, Novocastra, paraffin immunoperoxidase, original magnification X60)                                                                                                                                                                                                               ';
desc18  =  'Case 1 - Figure 8 </font><br><font id=normaltext>The large dysplastic lymphocytes are CD4+ T-cells (Clone 1F6, Novocastra, paraffin immunoperoxidase, original magnification X600)                                                                                                                                                                                                                                        ';
desc19  =  'Case 1 - Figure 9 </font><br><font id=normaltext>Scattered small lymphocytes are CD8+, and the large dysplastic lymphocytes are CD8 negative.  Most of the small lymphocytes at the edges of the tumor mass and infiltrating the epidermis (as shown in Figure 4)  are CD8+, reactive lymphocytes (not illustrated in this image) (Clone C8/144B, Dako Cytomation, paraffin immunoperoxidase, original magnification X600)';
desc110 =  'Case 1 - Figure 10</font><br><font id=normaltext>The lymphocytes are strongly CD30+ in a sheet-like distribution. (Clone BerH2, Neomarker, paraffin immunoperoxidase, original magnification X100)                                                                                                                                                                                                                        ';
desc111 =  'Case 1 - Figure 11</font><br><font id=normaltext>Virtually all of the large lymphocytes are strongly CD30+ with a membrane and Golgi pattern of staining (Clone BerH2, Neomarker, paraffin immunoperoxidase, original magnification X600)                                                                                                                                                                                 ';
desc112 =  'Case 1 - Figure 12</font><br><font id=normaltext>The epidermis strongly expresses epithelial membrane antigen (EMA) and the large lymphocytes are EMA- (Clone E29, Dako Cytomation, paraffin immunoperoxidase, original magnification X600)                                                                                                                                                                               ';
desc113 =  'Case 1 - Figure 13</font><br><font id=normaltext>Some of the large lymphocytes and scattered small lymphocytes have cytoplasmic expression of the cytolytic granule protein TIA-1. (Clone 2G9, Immunotech, paraffin immunoperoxidase, original magnification X600)                                                                                                                                                        ';
desc114 =  'Case 1 - Figure 14</font><br><font id=normaltext>The large lymphocytes lack expression of anaplastic lymphoma kinase  (ALK) protein. (Clone ALK01, Ventana, paraffin immunoperoxidase, original magnification X600)                                                                                                                                                                                                       ';
desc21  =  'Case 2 - Figure 1 </font><br><font id=normaltext>A mixed population of lymphocytes and histiocytes infiltrates the lobules and septa of the subcutaneous fat.  Hematoxylin and eosin, 100X                                                                                                                                                                                                                                ';
desc22  =  'Case 2 - Figure 2 </font><br><font id=normaltext>Abnormal medium size lymphocytes and histiocytes are present surrounding the adipocytes.  Note the apoptotic debris within some of the macrophages.  Hematoxylin and eosin, 200X                                                                                                                                                                                         ';
desc23  =  'Case 2 - Figure 3 </font><br><font id=normaltext>The abnormal lymphocytes have irregular, hyperchromatic nuclei with inapparent nucleoli, and sparse cytoplasm.  They rim the fat spaces and are mixed with macrophages with twisted nuclei, delicate chromatin, single nucleoli and abundant clear cytoplasm.  Some of the macrophages contain apoptotic debris.  Hematoxylin and eosin, 600X                            ';
desc24  =  'Case 2 - Figure 4 </font><br><font id=normaltext>The neoplastic lymphocytes are positive for CD2.  Immunoperoxidase stain for CD2, 200X                                                                                                                                                                                                                                                                                   ';
desc25  =  'Case 2 - Figure 5 </font><br><font id=normaltext>The neoplastic lymphocytes express CD8.  Immunoperoxidase stain for CD8, 200X                                                                                                                                                                                                                                                                                            ';
desc26  =  'Case 2 - Figure 6 </font><br><font id=normaltext>Granzyme B positive lymphoma cells rim the fat spaces and are present between fat cells.  Immunoperoxidase stain for granzyme B, 600X                                                                                                                                                                                                                                    ';
desc31  =  'Case 3 - Figure 1 </font><br><font id=normaltext>This clinical photograph shows a violaceous nodular lesion of the right earlobe                                                                                                                                                                                                                                                                                          ';
desc32  =  'Case 3 - Figure 2 </font><br><font id=normaltext>In this photomicrograph, one sees a vaguely nodular lymphoid infiltrate that occupies much of the dermis                                                                                                                                                                                                                                                                 ';
desc33  =  'Case 3 - Figure 3 </font><br><font id=normaltext>A partially follicular nature for the lymphoid infiltrate is better-seen in this photograph                                                                                                                                                                                                                                                                              ';
desc34  =  'Case 3 - Figure 4 </font><br><font id=normaltext>The lymphoid infiltrate is polymorphous in this area                                                                                                                                                                                                                                                                                                                     ';
desc35  =  'Case 3 - Figure 5 </font><br><font id=normaltext>Notable stromal vascularity is apparent.  The lymphoid cells in this field demonstrate modest nuclear atypia                                                                                                                                                                                                                                                             ';
desc36  =  'Case 3 - Figure 6 </font><br><font id=normaltext>Eosinophils are admixed throughout the infiltrate, as shown here                                                                                                                                                                                                                                                                                                         ';
desc37  =  'Case 3 - Figure 7 </font><br><font id=normaltext>Modest nuclear atypia is again evident in this photomicrograph                                                                                                                                                                                                                                                                                                           ';
desc41  =  'Case 4 - Figure 1 </font><br><font id=normaltext>Low power magnification of cutaneous follicular lymphoma                                                                                                                                                                                                                                                                                                                 ';
desc42  =  'Case 4 - Figure 2 </font><br><font id=normaltext>Higher magnification of cutaneous follicular lymphoma                                                                                                                                                                                                                                                                                                                    ';
desc43  =  'Case 4 - Figure 3 </font><br><font id=normaltext>CD20 stain of cutaneous follicular lymphoma                                                                                                                                                                                                                                                                                                                              ';
desc44  =  'Case 4 - Figure 4 </font><br><font id=normaltext>CD3 stain of cutaneous follicular lymphoma                                                                                                                                                                                                                                                                                                                               ';
desc45  =  'Case 4 - Figure 5 </font><br><font id=normaltext>CD21 stain of cutaneous follicular lymphoma. Note the tight meshworks of follicular dendritic cells                                                                                                                                                                                                                                                                      ';
desc46  =  'Case 4 - Figure 6 </font><br><font id=normaltext>CD10 stain of cutaneous follicular lymphoma showing strong expression                                                                                                                                                                                                                                                                                                    ';
desc47  =  'Case 4 - Figure 7 </font><br><font id=normaltext>Bcl-6 stain of cutaneous follicular lymphoma showing weak but definite staining of neoplastic B cells                                                                                                                                                                                                                                                                    ';
desc48  =  'Case 4 - Figure 8 </font><br><font id=normaltext>Bcl-2 staining of this case with strong expression                                                                                                                                                                                                                                                                                                                       ';

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