POSTER SESSION I Monday, February 28, 2005   —  9:30 AM - 12:00 Noon Convention Center, Exhibit Hall B HEMATOPATHOLOGY 138 Immunophenotypic Comparison of Peripheral Blood Stem Cells, Normal Bone Marrow Blasts and Leukemic Myeloid Blasts (1025) JM Alfardan, SH Kroft, FS Fuda, Y Xu, RW McKenna, NJ Karandikar - The University of Texas Southwestern Medical Center, Dallas, TX 139 In Situ Hybridization (ISH), Immunohistochemistry (IHC), and Gene Expression Profiling (GEP) for Determing Monoclonality in 61 Cases of Diffuse Large B-Cell Lymphoma (1027) MW Andres, RA Roberts, DJ Mustacich, G Ott, RD Gascoyne, DA Fuchs, MX Wang, RM Braziel, WC Chan, TM Grogan, LM Rimsza - University of Arizona, Tucson, AZ; Ventana Medical Systems, Inc, Tucson, AZ; British Columbia Cancer Agency, Vancouver, BC, Canada; Oregon Health Sciences Center, Portland, OR; University of Nebraska, Omaha, NE; University of Wurzburg, Wurzburg, Germany 140 MTAP Gene Deletions in Mantle Cell Lymphoma Are Associated with Lack of Protein Expression and Shorter Survival (1037) O Balague, S Marce, L Colomo, G Ott, L Leoni, D Colomer, E Campo - Hospital Clinic, University of Barcelona, Barcelona, Spain; University of Wurzburg, Wurzburg, Germany; Salmedix, Inc, San Diego, CA 141 Simultaneous Detection of Granulocyte Abnormalities in Blood and Bone Marrow of Patients with Myelodysplastic Syndrome (MDS) by Flow Cytometry (1039) RC Beck, JP Maciejewski, S Stahl, ED Hsi - Cleveland Clinic Foundation, Cleveland, OH 142 Apoptosis and Proliferation in the Spectrum of Post Transplant Lymphoproliferative Disorders (PTLD) (1040) J Blankenship, IT Yeh, P Saikumar, M Kinney, J Jagirdar - Univ of TX Health Science Ctr at San Antonio, San Antonio, TX 143 Epstein-Barr Virus Studies and Clinical Outcome in Hodgkin Lymphoma and Hodgkin Lymphoma-Like Post Transplant Lymphoproliferative Disorder (1048) S Chikkamuniyappa, MC Kinney, A Ehsan - UT Health Science Center, San Antonio, TX 144 CD34 Immunohistochemical Staining of Normal and Reactive Bone Marrow Biopsies (1050) A Choon, KM Kernek, M Czader, DP O'Malley, A Orazi - Indiana University School of Medicine, Indianapolis, IN 145 Lymphoproliferations with Dual (B- and T-Cell) Monoclonal Gene Rearrangements (1064) W Fan, JW Lee, A Chadburn, W Tam, YL Wang, G Frizzera - Weill Medical College-Cornell University, New York, NY 146 Cytogenetic Abnormalities Detected by Fluorescence In Situ Hybridization on Paraffin-Embedded Chronic Lymphocytic Leukemia/ Small Lymphocytic Lymphoma Lymphoid Tissue Biopsies (1066) MB Flanagan, M Sathanoori, LA Soma, FE Craig, U Surti, SH Swerdlow - University of Pittsburgh School of Medicine; University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 147 Myeloperoxidase Expression Differentiates Leukemic from Non-Leukemic Blasts (1068) FS Fuda, SH Kroft, JM Alfardan, Y Xu, RW McKenna, NJ Karandikar - UT Southwestern Medical Center, Dallas, TX 148 Expression of VEGF and VEGF Receptors in Acute Promyelocytic Leukemia (107) V Gasilionis, S Aboudola, PN Okoro, AR Kini - Loyola University Medical Center, Maywood, IL 149 MDMX Is Widely Expressed in Adult Pre-B Acute Lymphoblastic Leukemia (ALL) and Is a Potential Therapeutic Target (1081) X Han, TJ McDonnell, G Lozano, G Garcia-Manero, LJ Medeiros, GZ Rassidakis, CE Bueso-Ramos - UT MD Anderson Cancer Center (UTMDACC), Houston, TX; UTMDACC 150 Simultaneous DNA Content/Cytoplasmic Immunoglobulin Analysis Is a Sensitive Flow Cytometric Method for the Diagnosis of Plasma Cell Myeloma (1090) H Islam, M Lee, Y Shao, K Lin, L Alexa, S Jagannath, A Mazumder, G Inghirami, F Sen - New York University Medical Center, New York, NY; St. Vincent Cancer Center, New York, NY; NYU School of Medicine, New York, NY 151 PAX5 as a Useful, Specific Immunohistochemical Marker for B-Cell Lymphomas (1093) KC Jensen, Y Natkunam - Stanford Medical Center, Stanford, CA 152 Utility of RT-PCR and FISH for Detecting malt-1 Gene Rearrangements in MALT-Lymphomas (1105) S Konoplev, LV Abruzzo, LJ Medeiros, C Rosales, R Miranda, C Cromwell, LL Barron, A Glassman, P Lin - UT MD Anderson Cancer Center, Houston, TX; Truman Medical Center and University of Missouri, Kansas City, MO 153 Marginal Zone Lymphoma: A Retrospective Immunophenotypic Analysis (1106) CB Kost, JT Holden, KP Mann - Emory University, Atlanta, GA 154 Flow Cytometric Analysis of T-Cell Type Large Granular Lymphocytic Leukemias (1115) RB Lundell, L Hartung, SL Perkins, DW Bahler - University of Utah, Salt Lake City, UT 155 Separation of MDS Patients Based on an Acute Leukemia Predictive Analysis Model (1116) MR Mariappan, LN Ma, DA Arber - Stanford University Medical Center, Stanford, CA 156 Transcription Factor PU.1 Is a Useful Marker in Distinguishing Nodular Lymphocyte Predominant Hodgkin Lymphoma from Classical Hodgkin Lymphoma (1118) RC McCune, SI Syrbu, MA Vasef - University of Iowa Hospitals and Clinics, Iowa City, IA 157 Novel BCL-6 Binding Proteins Identified by LC-MS/MS Suggest A Broader Role for BCL-6 in B-Cell Function (1122) RR Miles, DK Crockett, MS Lim, KSJ Elenitoba-Johnson - University of Utah Health Sciences Center, Salt Lake City, UT; ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT 158 BCL2 Expression as a Prognostic Indicator in Subtypes of Diffuse Large B Cell Lymphoma (1127) V Neppalli, J Iqbal, BJ Dave, DL Pickering, S Dave, CP Hans, DD Weisenburger, TC Greiner, RD Gascoyne, G Ott, HK Mueller-Hermelink, WG Sanger, DE Horsman, A Rosenwald, J Delabie, RM Braziel, ES Jaffe, E Campo, JC Lynch, JM Connors, JM Vose, JO Armitage, TM Grogan, LM Staudt, WC Chan - UNMC, NCI-NIH, UAR and UOR; BCCA, Canada; UW, Germany; UB, Spain 159 The Number of Tumor-Infiltrating CD3+ and CD25+ Cells Positively Correlates with Clinical Response to Rituximab in Follicular Lymphoma Patients (1135) CY Park, SP Bohen, R Levy, R Warnke, Y Natkunam - Stanford University School of Medicine, Stanford, CA; Genentech Inc., South San Francisco, CA 160 Proteasome Inhibitor Bortezomib Induces Caspase-Dependent Apoptosis in Hodgkin Lymphoma Cell Lines and Synergies with TRAIL (1146) W Qiu, J Kung, X Peng, M Yegappan, ED Hsi - Cleveland Clinic Foundation, Cleveland, OH; University of Texas Southwestern, Dallas, TX 161 Flow Cytometry vs. FISH for Detection and Monitoring of Minimal Residual Disease and Recurrent Disease in Pediatric Acute Leukemias (1150) R Ramdall, L Tsao, G Bhagat, B Alobeid - Columbia University, New York, NY 162 Site-Specific Morphologic Variations in Extranodal Marginal Zone B-Cell Lymphoma (EMZL) (1151) A Rawal, B Schnitzer, WG Finn, R Valdez - University of Michigan Hosp., Ann Arbor, MI 163 Characterization of Variant Morphologic and Immunoarchitectural Patterns in Nodal Marginal Zone Lymphoma: A Study of 53 Cases (1155) ME Salama, RA Warnke, Y Natkunam - Stanford University, Stanford, CA 164 Downregulation of hOGG1 in Follicular Lymphomas May Not Be Due to Gene Deletion, an Evaluation by Fluorescent In Situ Hybridization (1158) AM Sheehan, A Patel, CC Chang - Vanderbilt University Medical Center, Nashville, TN; Baylor College of Medicine, Houston, TX; The Methodist Hospital, Houston, TX 165 Biologic Complexities of Prognostic Markers in B-Cell Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (1164) LA Soma, FE Craig, MA Melan, JA Kant, SH Swerdlow - University of Pittsburgh School of Medicine, Pittsburgh, PA 166 Effects of Rituximab Therapy on Immune System Recovery Following Chemotherapy (1166) CP Soupir, FI Preffer, RP Hasserjian - Massachusetts General Hospital; Harvard Medical School, Boston, MA 167 Aberrant Somatic Hypermutation in Post-Transplant Lymphoproliferative Disorders (1178) E Vakiani, L Pasqualucci, G Narayan, VV Murty, B Alobeid, G Bhagat - Columbia University, New York, NY; Columbia University, New York, NY 168 RAS Mutations Are Associated with Monocytic Differentiation in Myeloid Leukemias and Are an Adverse Prognostic Factor in Chronic Myelomonocytic Leukemia (CMML) (1180) JR Valbuena, GZ Rassidakis, E Estey, R Luthra, C Yin, LJ Medeiros, D Jones - MD Anderson Cancer Ctr, Houston, TX 169 Activation of mTOR and Its Downstream Effectors in ALK+ Anaplastic Large Cell Lymphoma (ALCL) (1182) F Vega, LJ Medeiros, C Atwell, F-X Claret, GZ Rassidakis - Baylor College of Medicine, Houston, TX; The University of Texas MD Anderson Cancer Center, Houston, TX 170 Proliferation Index and Follicular Lymphoma Grading: An Old Topic Revisited Low Histologic Grade Follicular Lymphoma with High Proliferation Index: Distinctive Morphologic and Clinical Features (1184) SA Wang, L Wang, EP Hochberg, NL Harris, RP Hasserjian - MGH, Boston, MA 171 Morphologic, Cytogenetic and Molecular Abnormalities in Therapy-Related Acute Promyelocytic Leukemia (1195) CC Yin, P Lin, JR Valbuena, D Jones, R Luthra, LJ Medeiros, AB Glassman - UT MD Anderson Cancer Center, Houston, TX 172 A Pyrosequencing Method for Quantitation of Mutated BCR-ABL Transcripts in Chronic Myelogenous Leukemia Patients with Imatinib Resistance (1196) CC Yin, R Luthra, J Galbincea, J Cortes, D Jones - UT MD Anderson Cancer Center, Houston, TX