POSTER SESSION IV Tuesday, March 1, 2005   —  1:00 - 4:30 PM Convention Center Exhibit Hall B PATHOLOGY OF LIVER & PANCREAS 177 Ampullary Carcinoma: Role of DNA Mismatch Repair Gene Defects in Pathogenesis (1260) NP Agaram, J Shia, DS Klimstra - Memorial Sloan-Kettering Cancer Center, New York, NY 178 Analysis of MSI and Cdx2 Expression in Adenocarcinomas of the Ampulla of Vater (1321) F Sessa, F Franzi, C Zampatti, D Furlan, C Capella - University of Insubria, Varese, Italy; Ospedale di Busto Arsizio, Busto Arsizio, Varese, Italy 179 Detection of Lymphatic Invasion in Pancreatic Cancers Based on Immunohistochemistry of D2-40 (1323) Y Shimizu, S Ban, T Mitsuhashi, F Ogawa, T Hirose, M Shimizu - Saitama Medical School, Iruma, Saitama, Japan 180 Double Immunohistochemical Staining with MUC4/P53 Is Useful in the Distinction of Pancreatic Adenocarcinoma from Chronic Pancreatitis- A Tissue Microarray Based Study (1313) JW Nash, A Bhardwaj, P Wen, C Barbacioru, S Jones, WL Frankel - Ohio State University, Columbus, OH 181 Intestinal and Oncocytic Variants of Pancreatic Intraepithelial Neoplasia (PanIN): A Morphologic and Immunohistochemical Study (1262) J Albores-Saavedra, J Wu, T Crook, RH Amirkhan, L Jones, RH Hruban - LSUHSC, Shreveport, LA; Dallas Veterans Affairs Medical Center, Dallas, TX; The Johns Hopkins Medical Institutions, Baltimore, MD 182 Expression of ZO-1 in Pancreatic Intraepithelial Neoplasia (PanIN) (1284) T Cibull, S Badve, A Thomas, R Saxena - Indiana University, Indianapolis, IN 183 Invasive Micropapillary Carcinoma of the Ampullo-Pancreatobiliary Region (1303) SH Khayyata, O Basturk, F Khanani, H Nassar, J Cheng, NV Adsay - Wayne State University, MI 184 Expression of Pancreatic Duodenal Transcription Factor 1 (PDX-1) and CDX-2 in Mucinous Cystadenocarcinomas of the Pancreas and Ovary (1309) X Lin, C Deng, JF Silverman, M Tung, YL Liu - Allegheny General Hospital, Pittsburgh, PA 185 Immunohistochemistry as a Helpful Adjunct in the Differential Diagnosis of Intraabdominal Carcinomatosis Originating from the Pancreas Versus Ovary (1264) R Ali-Fehmi, O Basturk, JD Cheng, I Khalifeh, S Bandyopadhyay, E Silva, H Nassar, NV Adsay - Wayne State University, MI; MD Anderson Cancer Center TX 186 Ovarian-Type Stroma in Hepatobiliary Mucinous Cystadenoma and Pancreatic Mucinous Cystic Neoplasms: An Immunohistochemical Study (1307) MM Lam, PE Swanson, MP Upton, MM Yeh - University of Washington, Seattle, WA 187 Intraductal and Papillary Variants of Pancreatic Acinar Cell Carcinoma: A New Addition to the Challenging Differential Diagnosis of Intraductal Neoplasms (1271) O Basturk, G Zamboni, D Klimstra, A Andea, NS Kamel, P Capelli, JD Cheng, NV Adsay - Wayne State University, MI; Verona University, Italy; Memorial Sloan Kettering Cancer Center, NY 188 Will the Real Mucinous Carcinoma of the Pancreas Please Stand Up?: A Reappraisal of the Terminology, Classification and Differential Diagnosis of "Mucinous" Carcinomas in the Ampullo-Pancreatobiliary Region (1259) VN Adsay, F Khanani, O Basturk, A Andea, JD Cheng - Wayne State University, MI 189 Differential Expression of Mucins, MIB-1 and p53 in Mucinous Tumors of the Pancreas (1277) G Cai, A Simsir, H Yee, L Chiriboga, P Kefalides, J Cangiarella - New York University - Bellevue Hospital Center, New York University School of Medicine, New York, NY 190 Two Major Types of Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas: Their Distinct Histological and Mucin Phenotypic Features (1270) S Ban, Y Naitoh, T Sakurai, M Kuroda, M Shimizu - Saitama Medical School, Iruma, Saitama, Japan; Kyoto University Hospital, Kyoto, Japan; Fujita Health University School of Medicine, Toyoake, Aichi, Japan 191 Analysis of Molecular Alterations and Differentiation Pathways in Intraductal Oncocytic Papillary Neoplasm of the Pancreas (1283) SM Chung, RH Hruban, C Iacobuzio-Donahue, NV Adsay, SY Zee, DS Klimstra - Memorial Sloan-Kettering Cancer Center, New York, NY; Johns Hopkins Universtiy Hospitals, Baltimore, MD; Karmanos Cancer Institute and Wayne State University, Detroit, MI; Albert Einstein School of Medicine, New York, NY 192 The Effect of Sindbis Viral Vectors on the N-Nitroso-Bis(2-Oxopropyl)Amine(BOP) Induced Hamster Pancreatic Ductal Adenocarcinoma and Cholangiocarcinoma (1310) Q Liu, AB West, S Merali, B Levin, D Meruelo, A Pellicer - NYU School of Medicine, New York, NY 193 Analysis of Expression of CDX2 Protein in Metastatic Colorectal Carcinoma in the Liver and Primary Cholangiocarcinomas (1290) R Gupta, M Abecassis, P Kashireddy, MS Rao - The Feinberg School of Medicine, Northwestern University, Chicago, IL 194 Expression of MUC1, MUC2, MUC5AC and CDX2 in Carcinomas of the Gallbladder and Extrahepatic Bile Duct (1342) H Zhang, O Basturk, M Othman, JD Cheng, S H. Khayyata, A Maitra, R Hruban, NV Adsay - Wayne State University, MI; The John Hopkins University, MD 195 Expression of Two Novel Tumor Markers, Maspin and Tubulin beta Polypeptide (TUBB), in Biliary Cancers (1278) D Cao, K Kassaui, P Argani, C Neumann, L Ho, JL Abbruzzese, M Ouellette, A Maitra - The Johns Hopkins Hospital, Baltimore, MD; MD Anderson Cancer Center, Houston, TX 196 Comparison of Cytokeratin 7 and 20 Staining in Whole Tissue Block and Mock-Radiologically Obtained Needle Cores Biopsies: A Potential Cause of False-Positive Results Due to Limited Tissue Samples (1274) D Bosler, NS Goldstein - William Beaumont Hospital, Royal Oak, MI 197 Homozygous Deletion of the MTAP Gene in Invasive Adenocarcinoma of the Pancreas and in Periampullary Cancer: A Potential New Target for Therapy (1294) SR Hustinx, RH Hruban, LM Leoni, P Argani, R Ashfaq, MG Goggins, SE Kern, A Maitra - Johns Hopkins University, Baltimore, MD; Academic Medical Center, Amsterdam, Netherlands; Salmedix, Inc., San Diego, CA; University of Texas Southwestern Medical Center, Dallas, TX 198 Concordant Loss MTAP and p16/CDKN2A Expression in Pancreatic Intraepithelial Neoplasia: Evidence of Homozygous Deletion in a Non-Invasive Precursor Lesion (1292) S Hustinx, A Maitra, LM Leoni, R Ashfaq, MG Goggins, C Iacobuzio-Donahue, SE Kern, RH Hruban - Johns Hopkins University, Baltimore, MD; Academic Medical Center, Amsterdam, Netherlands; Salmedix, Inc, San Diego, CA; University of Texas Southwestern Medical Center, Dallas, TX 199 Differentially Expressed Genes in Pancreatic Ductal Adenocarcinomas Identified through Serial Analysis of Gene Expression: An Update (1293) SR Hustinx, D Cao, RH Hruban, N Sato, ST Martin, D Sudhir, C Iacobuzio-Donahue, SE Kern, MG Goggins, A Pandey, A Maitra - Johns Hopkins University, Baltimore, MD; Academic Medical Center, Amsterdam, Netherlands; Institute of Bioinformatics, Barcelona, India 200 Maspin Is Overexpressed in the Majority of Pancreatic Ductal Adenocarcinomas and Pancreatic Intraepithelial Neoplasia (PanIN) Lesions: A Potential Biomarker for Early Detection (1319) S Salaria, M Cronin, E Kim, Q Zhang, A Maitra, C Neumann, RH Hruban, MG Goggins, JL Abbruzzese, L Ho - Johns Hopkins University, Baltimore, MD; U.T. M. D. Anderson Cancer Center, Houston, TX 201 Immunohistochemical Labeling for Deoxycytidine Kinase (dCK) in Pancreatic Cancer Correlates with Response to Gemcitabine (1320) V Sebastiani, S Witzel, F Ricci, D Laheru, C Iacobuzio-Donahue - The Johns Hopkins Hospital, Baltimore, MD 202 The Immunohistochemical Characterization of EGFR Expression in Pancreatic Adenocarcinoma- A Tissue Microarray Based Study (1273) A Bhardwaj, JW Nash, C Barbacioru, WM Smith, WL Frankel - Ohio State University, Columbus, OH 203 The Expression of Proxisome Proliferator Activated Receptor Gamma (PPARg in Ductal Pancreatic Carcinoma: A Correlative Study with Angiogenic Factors (VEGF and CD 34) (1285) Y Dancer, C Heard, R Shi, J Albores-Saavedra - Louisiana University Health Science Center, Shreveport, LA 204 The Tubulin Beta-4 Polypeptide (TUBB4), a Marker of Resistance to Taxanes, Is Overexpressed in Pancreatic Intraepithelial Neoplasia and Pancreatic Ductal Adenocarcinoma (1311) A Maitra, D Cao, K Lee, A Itami, RH Hruban, M Ouellette - The Johns Hopkins Hospital, Baltimore, MD; Omaha, NE 205 Lipid-Rich Pancreatic Endocrine Neoplasms (PENs): Characterization of a Clinicopathologically Distinct Variant (1324) RS Singh, O Basturk, G Zamboni, DS Klimstra, R Chetty, S La Rosa, JD Cheng, CV Capella, NV Adsay - Wayne State University, MI; Verona University, Italy; Memorial Slaoan-Kettering Cancer Center, NY; University of Insubria, Italy; University of Toronto, Canada 206 Lymphatic Vessel Density and VEGF-C Expression Correlate with Malignant Behavior in Human Pancreatic Endocrine Tumors (1318) L Rubbia-Brandt, B Terris, E Giostra, B Dousset, P Morel, MS Pepper - Geneva University Hospital, Geneva, Switzerland; Hospital Cochin, Paris, France; Hospital Cochin, Paris, France; Hospital Cochin, Paris, France 207 Pathologic Findings in Gallbladders Resected during Morbid Obesity Operations (1272) O Basturk, G Altinok, L Budev, A Hildebrandt, JD Cheng, NV Adsay - Wayne State University, MI