Gynecologic Pathology
Thursday, March 3, 2005 - 7:30 PM
Rivercenter Salon E
Moderator:
Christopher P. Crum Brigham & Women's Hospital Boston, MA
Click on each slide thumbnail image for an enlarged view
Case 1
Submitted by: Teri A. Longacre Stanford University Medical Center Stanford, CA
Clinical Summary:
A 48-year old woman, gravida 2 para 0, had irregular menses and abnormal Pap smear. The uterus was moderately enlarged on physical examination. Colposcopic exam was normal. Endocervical and endometrial curettage had similar findings.
Case 2
Submitted by: C. Blake Gilks University of British Columbia Vancouver, BC, Canada
Clinical Summary:
This 69 year old woman presented with post-menopausal bleeding and an endometrial biopsy showed "adenocarcinoma of endometrioid type, grade 2/3”. The submitted slide is from the subsequent hysterectomy and bilateral salpingo-oophorectomy specimen and is taken from the uterine corpus.
Case 3
Submitted by: Phyllis C. Huettner Washington University Medical Center St. Louis, MO
Clinical Summary:
The patient is a 59 year old woman who presented with abdominal distention. At age 42 a vaginal hysterectomy was performed for fibroids. At age 50 the patient had a left mastectomy and axillary node dissection for stage Ia breast cancer. Her course was complicated by a chest wall recurrence at age 54 which was treated with radiation therapy. She was well until a month before presentation when she noted abdominal distention. CT scan of the abdomen showed ascites and peritoneal implants. CA-125 was 226 (normal - 0 to 34). Exploratory laparotomy, bilateral salpingo-oophorectomy, omentectomy and radical tumor de-bulking were performed. The ovaries were mildly enlarged but firm. Multiple peritoneal implants were present.
Case 4
Submitted by: Marisa R. Nucci Brigham and Women's Hospital Boston, MA
Clinical Summary:
39 year old woman with 10 cm bi-lobed solid and cystic, partially calcified pelvic mass on CT scan. At surgery, the mass only involved the omentum. Preoperative CA-125 level was 145.
