Scott E. Kilpatrick, M.D., Pathologists Diagnostic Services, Forsyth Medical Center, Winston-Salem, NC and Omar P. Sangueza, M.D., Wake Forest University Baptist Medical Center, Winston-Salem, NC
The course will provide a case-based presentation focusing on specific and common diagnostic dilemmas in bone and superficial and deep soft tissue surgical pathology. We will emphasize those lesions that are especially problematic, benign lesions mimicking malignant ones, malignant lesions mimicking benign processes, and adult sarcoma. Examples include the diagnosis of lipoma vs. atypical lipoma, enchondroma vs. low grade chondrosarcoma, hemangioma vs. angiosarcoma, non-gynecologic leiomyoma vs. leiomyosarcoma, and giant cell containing lesions of bone. Non-mesenchymal lesions mimicking sarcoma, such as sarcomatoid carcinoma and desmoplastic melanoma, will also be presented in case-based format. When necessary, the role of fine needle aspiration biopsy will be illustrated and discussed. Although emphasis will be predominantly placed on light microscopic features, the use of ancillary techniques, including immunohistochemistry and cytogenetics, will be mentioned when applicable to the particular case. Upon completion of the course, the participant should be able to 1) confidently approach the differential diagnosis of the more common problematic areas in bone and soft tissue pathology, 2) discuss and recognize diagnostic pitfalls in musculoskeletal pathology, 3) understand the role and limitations of fine needle aspiration biopsy, and 4) cost-effectively utilize ancillary techniques in the work-up of these lesions.
The course is designed for pathology residents and general surgical pathologists seeking a better understanding of the histologic features of some of the more common bone and soft tissue tumors. A limited number of glass slide sets will be available for advance mailing prior to the meeting. The entire presentation on CD-ROM will be mailed to all attendees after the meeting. An extensive syllabus will be distributed at the course.