POSTER SESSION IV Tuesday, February 14, 2006   —  1:00 - 4:30 PM Exhibit Level PATHOBIOLOGY 191 In Search of a "joker" Factor In Cell Signaling Pathway In Human Malignant Tumors. 4EBP1 As A Very Good Candidate (1362) S Ramon y Cajal, J Jimenez, E Llonch, F Rojo, M Cuatrecasas, C Iglesias, J Castellvi, A Garcia, J Baselga, H Allende - Vall d'Hebron University Hospital, Barcelona, Spain 192 Expression Of The Novel Gene RSK4 In Human Tumors: A mRNA Study (1364) C Ruiz-Marcellan, L Lopez, M Lleonart, J Castellvi, A Garcia, V Fumanal, J Hernandez, I de Torres, F Rojo, A Lopez, S Ramon y Cajal - Vall Hebron University Hospital, Hospital S Pere de Ribes, Barcelona, Spain 193 Overexpression Of Wild-Type p53 Induced Phosphatase (Wip1) Abrogates p38 MAPK-p53-Wip1 Pathway, Contributing To The Tumorigenesis Of Human Breast Cancers (1373) E Yu, Y Ahn, HS Yoon, G Gong, J Choi - University of Ulsan College of Medicine Asna Medical Center, Seoul, Korea 194 MKK4 Activation Inhibits Metastatic Colonization of the Lung (1356) TL Lotan, DJ Vander Griend, M Kocherginsky, K Macleod, CW Rinker-Schaeffer - University of Chicago, Chicago, IL; Johns Hopkins University, Baltimore, MD 195 Loss Of CBX7 Expression Is A Common Event In Human Malignancies. (1372) G Troncone, P Pallante, M Sanchez-Beato, MT Berlingieri, A Iaccarino, M Russo, L Palombini, A Fusco - UniversitB degli Studi di Napoli Federico II, Naples, Italy; UniversitB degli Studi di Napoli Federico II, Italy, Naples, Italy; Centro Nacional de Investigaciones Oncologicas, Madrid, Spain; NOGEC (Naples Oncogenomic Center)-CEINGE, Biotecnologie Avanzate, Naples, Italy 196 CDX-2 Immunostaining in Pseudomyxoma Peritonei (1360) D Nonaka, S Kusamura, D Baratti, P Casali, R Younan, M Deraco - New York University Medical Center, New York, NY; National Cancer Institute, Milan, Italy 197 The Role of Regulatory T-cells in Immunologically Preparing Secrertory Endometrium For Fetal Implantation (1366) HA Sattar, AN Husain, X Fu, A Montag, M Tretiakova, T Krausz - University of Chicago Hospitals, Chicago, IL 198 Immunosuppressive Alterations in Axillary Sentinel Lymph Nodes in Early Breast Cancer (1353) JR Lee, K Subbannan, A Kallab, DH Munn - Medical College of Georgia, Veterans Affairs Medical Center, Augusta, GA 199 Mutational Profile of Sentinel Lymph Node Metastasis in Breast Cancer: Pathobiology Implication (1355) YL Liu, X Lin, JF Silverman, RS Saad, SD Finkelstein - Allegheny General Hospital, RedPath Integrated Pathology, Inc, Pittsburgh, PA 200 Effects of a Monoclonal Anti-±v²3 Antibody on Blood Vessels - A Pharmacodynamic Study (1375) D Zhang, T Pier, D Alberti, DG McNeel, G Wilding, A Friedl - University of Wisconsin-Madison, Madison, WI 201 Transgenic Mice Overexpressing Human 8-oxoguanine DNA Glycosylase (hOGG) in Mitochondria Develop Obesity, Hepatosteatosis and Female Infertility (1376) H Zhang, Q Huang, L Li, Y Wang, MW Zhou, G Ranganathan, PA Kern, PM Iannaccone, CY Fan - University of Arkansas for Medical Sciences, Little Rock, AR; City of Hope Medical Center, Duarte, CA; National Center for Toxicological Research, Jefferson, AR; Northwestern University Medical School, Chicago, IL 202 Mitochondrial DNA  Damages Enhance  the Cell Killing  Effects  of Cisplatin  in Human  Hepatoma  Cells via Increased Intracellular Free Radical Production (1377) H Zhang, J Trullols, M Higuchi, BR Smoller, CY Fan - University of Arkansas for Medical Sciences, Little Rock, AR 203 Down-Regulation of BCRP/ABCG2 During Tumorigenesis In Vivo (1351) AV Herdman, N Gupta, PM Martin, S Miyauchi, H Hu, RG Martindale, R Podolsky, RB Hessler, V Ganapathy - Medical College of Georgia, Augusta, GA; Oregon Health Sciences University, Portland, OR 204 The Use Of Pooled Reference RNA In Leu Of Matched Normal Cells Results In Significant Discrepancies When Compared To Neoplastic Cells On An Expression Array (1359) WD Mojica, LA Hawthorn, A Arshad - University at Buffalo; Roswell Park Cancer Institute, Buffalo, NY 205 Galectin-4 Expression In Carcinoid Tumors (1365) K Rumilla, LA Erickson, AK Erickson, RV Lloyd - Mayo Clinic, Rochester, MN; South Dakota State University, Brookings, SD 206 Refractory ITP: Therapy-related Histopathologic Changes in Spleens (1340) S Allen, R Chiu, L Baldridge, A Orazi, CH Dunphy, DP O'Malley - Indiana University, Indianapolis, IN; University of North Carolina, Chapel Hill, NC 207 Contributions of Somatic Mismatch Repair Defects to a Differential Microsatellite Profile of MEN 2A C-Cell and Adrenal Medullary Hyperplasias (1343) A Blanes, JJ Sanchez-Carrillo, SJ Diaz-Cano - University of Malaga School of Medicine, Malaga, Spain; King's College Hospital, London, United Kingdom 208 Expression of Peroxisome Proliferator Activated Receptor Gamma (PPAR-³) in Pancreatic Ductal Adenocarcinoma (PDAC) and Pancreatic Intraepithelial Neoplasia (PanIN) (1345) Y Dancer, M Moghadamfalahi, J Thibodeaux, J Albores-Saavedra - The Methodist Hospital, Houston, TX; Lousiana State University, Shreveport, LA 209 Decreased Fucose Expression Alters the Interaction of Human Breast Cancer Cells with Matrices and Endothelium In Vitro (1374) K Yuan, G Rezonzew, D Kucik, GP Siegal - UAB, VAMC, Birmingham, AL 210 Diagnostic Value of D2-40 in Separating Metastatic Seminoma from Other Metastatic Malignancies (1347) C Deng, YL Liu, RS Saad, SS Shen, Q Cai, JF Silverman - Allegheny General Hospital, Pittsburgh, PA; The Methodist Hospital, Houston, TX 211 Lymphotoxin Pathway Directed, AIRE-Independent Central Tolerance toArthritogenic Type-II Collagen (CII) (1354) W Liu, RK Chin, M Zhu, Y-X Fu - The University of Chicago, Chicago, IL 212 New Vectors For Prostate Cancer Gene Therapy. Expression Of Kaposi[apos]s Sarcoma-Associated Herpes Virus (KSHV) Cyclin D Homologue, K-Cyclin Exerts A Marked Cytotoxic Effect And Increases Sensitivity To Chemotherapy (1349) M Diaz-Fuertes, J Hernandez-Losa, C Parada, R Sanchez, L Lopez, J Jimenez, S Ramon y Cajal - Vall d'Hebron University Hospital, Barcelona, Spain 213 Cell Surface Molecule R9.14 is Expressed by Monoblastic Leukemia of FAB M5 Type as well as Reed-Sternberg Cell Lines and Anaplastic Large Cell Lymphoma Cell Lines (1378) M Zhou, FM Fadl El Mola, H Chang, J Cohn, R Karim, D Hogge, D Banerjee - British Columbia Cancer Agency, British Columbia Cancer Research Centre Vancouver, BC, Canada; Prince Margaret Hospital, Ontario Cancer Institute, Toronto, ON, Canada 214 Transcriptional Regulation Of Valosin-Containing Protein (VCP) Gene, Which Is Involved In Cell Proliferation And Metastasis, Through PBX1 (Pre B Cell Leukemia Transcription Factor 1) (1371) Y Tomita, Y Qiu, Z Zhang, I Nakamichi, E Morii, K Aozasa - Osaka University Graduate School of Medicine, Suita, Osaka, Japan; Medical School of Tongji University, Shanghai, China 215 Slit2 Expression in Human Neoplasms: A Preliminary Tissue Microarray Study of 839 Cases (1344) N Chen, XQ Chen, J Gong, B Yang, YT He, W Yin, XL Liu, XJ Wang, Q Zhou - West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China 216 Oligonucleotide And Immunohistochemical Analysis Of Claudin-7 In Normal Human Epithelia And Their Malignant Counterpart (1361) HS Qureshi, G Hampton, W El-Rifai, HF Frierson - University of Virginia, Charlottesville, VA; Genomics Institute of the Novartis Research Foundation, San Diego, CA 217 The Biological And Pathological Fetures Of Epstein-Barr Virus(EBV)-Associated Gastric Carcinoma. (1352) R Hino, H Uozaki, M Fukayama - Tokyo University, Graduate School of Medicine, Tokyo, Bunkyo-ku, Hongo, Japan 218 Evolutionary Relationship Of Annexin Genes In Human By Bioinformatics Methods (1350) YI Elshimali, D Chen, C Aoyama, P Liu - Olive View UCLA Medical Center, Sylmar, CA