—  SPECIALTY CONFERENCE  —

Dermatopathology

Case 1 - Sebaceous Carcinoma

David Cassarino
Stanford University School of Medicine
Stanford, CA





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Clinical History
A 60 year-old male presented with a several month history of an enlarging, occasionally bleeding, lesion on his scalp. Clinical examination showed a 1.5 cm ulcerated plaque on the left scalp; the clinical differential diagnosis was SCC versus BCC.


Case 1 - Slide 1
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Case 1 - Figure 1
Scalp tumor with deep dermal invasion, 2X

Case 1 - Figure 2
Infiltrating tumor with basaloid to squamoid differentiation and clear cell areas, 4X

Case 1 - Figure 3
Higher power of squamoid-appearing area with scattered large, pleomorphic clear cells (arrow), 20X

Case 1 - Figure 4
Juxtaposition of squamoid (left) and clear cell areas (right) with frequent mitoses (Figure 5), 20X

Case 1 - Figure 5