PROFFERED PAPERS
Monday, March 26   —  8:00 AM   —  CC 5 A/B


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Section D - BREAST PATHOLOGY
Chaired by: Timothy Jacobs and Donald Weaver



TimeTitle and AuthorsItinerary
Planner
8:00 BRCA2 Deficiency and EMSY Amplification; Possible Mutually Exclusive Genetic Events in the Development of Breast Cancer (88)
AL Bane, N Weerasooriya, IL Andrulis, FP O'Malley Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada; Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
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8:15 Using Morphology and Phenotype To Predict BRCA1 Mutation Carrier Status in Breast Cancer (173)
AM Mulligan, N Weerasooriya, IL Andrulis, FP O'Malley Mount Sinai Hospital, Toronto, ON, Canada; Toronto, ON, Canada
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8:30 Sporadic Basal-Like Breast Carcinomas Harbour BRCA1 Gene Promoter Methylation and sox2 Overexpression: Similarities with BRCA1-Germ Line Mutated Tumours (199)
SM Rodriguez-Pinilla, D Sarrio, G Moreno-Bueno, Y Rodriguez-Gil, MA Martinez, L Hernandez, D Hardisson, JS Reis-Filho, J Palacios CNIO; Hospital Universitario 12 de Octubre; and Hospital La Paz, Madrid, Spain; Institute of Cancer Research, London, United Kingdom; HHUU Virgen del Rocio, Sevilla, Spain
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8:45 Immunophenotypic Profile of the Basal-Like Subtype of Invasive Breast Carcinomas: Influence on Diagnosis and Therapy (128)
PM Kim, LC Goldstein, SE Tirrell, TS Barry, SJ Kussick, PL Kandalaft, AM Gown PhenoPath Laboratories, PLLC and IMPRIS, Seattle, WA
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9:00 Array Comparative Genomic Hybridization and Immunophenotype Analysis of a Series of 88 Ductal Carcinomas In Situ of the Breast (221)
A Vincent-Salomon, N Gruel, C Lucchesi, V Raynal, G Pierron, B Sigal-Zafrani, P Freneaux, M Lae, RJ Salmon, A Fourquet, X Sastre-Garau, O Delattre - Institut Curie, Paris, France
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9:15 The “MINO” Mouse Model of DCIS Reveals a Genetically Stable Precancer Stem Cell with a Programmed Malignant Potential (96)
AD Borowsky, P Damonte, JP Gregg, QA Chen, LJT Young, JG Hodgson UC Davis, Davis, CA; UC Davis, Sacramento, CA; UCSF, San Francisco, CA
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9:30 RECESS, EXHIBITS, POSTER SESSION I  
11:00 Clinical and Pathologic Features of Ductal Carcinoma In Situ Associated with the Presence of Flat Epithelial Atypia: An Analysis of 441 Cases (104)
L Collins, S Schnitt, N Achacoso, L Nekhlyudov, S Fletcher, R Haque, L Habel Beth Israel Deaconess Med. Ctr. and Harvard Medical School, Boston, MA; Northern California Kaiser Permanente, CA; Harvard Pilgrim Health Center, Boston, MA; Southern California Kaiser Permanente, CA
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11:15 Morphological and Molecular Evolutionary Pathways of Low Grade Breast Cancers and Their Putative Precursor Lesions (80)
T Abdel-Fatah, DG Powe, Z Hodi, JS Reis-Filho, A Lee, IO Ellis Nottingham University, Nottingham, United Kingdom; Institute of Cancer Research, London, UK
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11:30 Monomorphic Epithelial Proliferations (MEPs): A Distinctive Subtype of Epithelial Hyperplasia and Evidence Suggesting They Are the Precursor Lesion of Some Ipsilateral Breast Failure Carcinomas in Patients Treated with Breast Conserving Therapy (129)
NS Goldstein, F Vicini - William Beaumont Hospital, Royal Oak, MI
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11:45 Clinical, Histopathologic, and Biologic/Molecular Features of Microglandular Adenosis with Transition into In-Situ and Invasive Carcinoma (152)
I Khalifeh, C Albarracin, Y Wu, N Sneige, M. D. Anderson Cancer Center, Houston, TX
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