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Vascular Pathology: From Vasculitis to Vasculopathy to Vascular Rejection
Volker Nickeleit, M.D.
J. Charles Jennette, M.D.
Click on each Section number below to display the text and references for that section
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This short course will deal with blood vessels and not lymphatic vessels, and thus will focus on pathologic changes in arteries, arterioles, capillaries, venules and veins.
Vasculitis is inflammation of blood vessels, and thus can affect any tissue and organ. Accurate diagnosis of vasculitis is based on correlation of the pathologic features with clinical, serologic, microbiologic and immunopathologic data.
The following section briefly highlights key aspects characterizing different vasculopathies commonly encountered by the pathologist. It is far beyond the scope of this handout to provide detailed information on the pathophysiology of each vasculopathy. We focus primarily on morphological aspects.
Many different disease processes can affect the arteries, arterioles and capillaries in solid organ transplants. Vascular changes are clinically significant since they determine long-term graft function and survival.
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