Jonathan L. Hecht, M.D., Ph.D., Beth Israel Deaconess Medical Center, Boston MA, Theonia Kamman Boyd, M.D., Children’s Hospital, Boston MA and Robert Padera, M.D., Ph.D., Brigham and Women’s Hospital Pathology, Boston MA
Classic features of chromosomal anomalies in newborns and children are often more subtle in fragmented fetal tissue received on the surgical bench. We will describe the techniques for examining tissues from induced abortions and fetal losses with emphasis on when to use special testing (x-rays, cytogenetics, molecular genetics, microbiology). We will provide a vocabulary and report format that will facilitate specialist consultation and correlation with ultrasound findings.
This course is designed for general pathologists and residents. Although not specifically intended for specialists in pediatric pathology or genetics, they will find the material useful and thorough. We will use both lecture and case discussion formats. We will not give survey lectures on the various syndromes, but rather concentrate on putting names to gross morphology and microscopic examination. Upon completion of the course, participants should be able to identify and concisely describe major anomalies involving tissues most commonly identifiable on gross evaluation: limbs, face, and selected internal organs. Microscopic pathology will cover not only normal histology at various stages of gestation but will also highlight important abnormal findings. A comprehensive syllabus will be distributed at the course and a post-course CD–ROM will include relevant tables and color photographs from the lectures mailed after the meeting.
This course may be used for CME credits or SAMs credits.