—  SHORT COURSE #07  —

An Approach to the Diagnosis of Bladder Lesions in Biopsy and Transurethral Resection Specimens

Section 1 - WHO (2004)/ISUP Classification of Bladder Tumors

Mahul B. Amin, MD
Jesse K. McKenney, MD


Normal
  • Normal *

Hyperplasia
  • Flat Hyperplasia

Flat Lesions with Aytpia
  • Reactive (Inflammatory) Atypia

  • Atypia of Unknown Significance

  • Dysplasia (Low-grade Intraurothelial Neoplasia)

  • Carcinoma In Situ (High-grade Intraurothelial Neoplasia)**

Papillary Neoplasms
  • Inverted Papilloma

  • Papilloma

  • Papillary Neoplasm of Low Malignant Potential (PUNLMP)

  • Papillary Carcinoma, Low grade

  • Papillary Carcinoma, High grade
*May include cases formerly diagnosed as "mild dysplasia"

** Includes cases with "severe dysplasia"