/* Sequence of slide descriptions */ desc01 = 'Case 1 - Figure 1 - The tumor is cystic and hemorrhagic and surrounded by a lymphoplasmacytic infiltrate and fibrosis, 20x. '; desc02 = 'Case 1 - Figure 2 - The lymphoid infiltrate focally forms germinal centers, 100x. '; desc03 = 'Case 1 - Figure 3 - The eosinophilic spindle cell component shows bland cytomorphology and is arranged in fascicular to slightly storiform pattern, 200x. '; desc04 = 'Case 1 - Figure 4 - Hemorrhage is noted within the bland, eosinophilic spindle cell component, 100x. '; desc05 = 'Case 1 - Figure 5 - Cystic areas filled with eosinophilic proteinaceous fluid are noted, 100x. '; desc06 = 'Case 1 - Figure 6 - The lymphoplasmacytic infiltrate is intimately associated with the spindle cells, 100x. '; desc07 = 'Case 1 - Figure 7 - Hemosiderin deposition is focally prominent, 100x. '; desc08 = 'Case 2 - Figure 1 - The tumor extends from the deep reticular dermis to subcutaneous tissue and displays a vaguely nodular architecture. '; desc09 = 'Case 2 - Figure 2 - Higher magnification view of the tumor. '; desc10 = 'Case 2 - Figure 3 - The nodules are composed of sheets of spindled cells aranged in short fascicles. Intratumoral and peripheral collections of lymphocytes can be appreciated. '; desc11 = 'Case 2 - Figure 4 - The tumor cells have indistinct cell borders, lightly eosinophilic cytoplasm and vesicular nuclei with prominent nucleoli. '; desc12 = 'Case 2 - Figure 5 - Focally, tumor cells dissect through dermal collagen forming anastamosing channels. '; desc13 = 'Case 2 - Figure 6 - Tumor cells are negative for S100 protein. '; desc14 = 'Case 2 - Figure 7 - Tumor cells are negative for cytokeratin AE1/AE3 '; desc18 = 'Case 3 - Figure 1 - Scanning magnification demonstrated a myxoid tumor involving the deep dermis and subcutis. '; desc19 = 'Case 3 - Figure 2 - The tumor was composed of randomly arranged cells embedded in a prominent myxoid stroma. '; desc20 = 'Case 3 - Figure 3 - The tumor cells were relatively bland spindled to stellate cells with hyperchromatic nuclei. '; desc21 = 'Case 3 - Figure 4 - High power view demonstrating the spindled and stellate tumor cells. '; desc22 = 'Case 3 - Figure 5 - Within the tumor there were ecstatic thin-walled vessels. '; desc23 = 'Case 3 - Figure 6 - In some areas there were delicate capillaries in the stroma. '; desc24 = 'Case 3 - Figure 7 - The tumor infiltrated through the subcutaneous fat that in areas resulted in a honeycomb pattern. '; desc25 = 'Case 3 - Figure 8 - Scattered multinucleated tumor cells were present. '; desc26 = 'Case 3 - Figure 9 - There was a focal area that was more cellular. In this area the tumor cells had a storiform growth pattern. '; desc27 = 'Case 4 - Figure 1 - Low-power view shows an ill-defined, cellular dermal neoplasm with infiltration of superficial parts of the subcutis. '; desc28 = 'Case 4 - Figure 2 - Plump spindled tumour cells are arranged in confluent nests and bundles. Tumour cells contain a pale eosinophilic or clear cytoplasm and enlarged nuclei. '; desc29 = 'Case 4 - Figure 3 - Scattered multinucleated giant cells (wreath-like giant cells) are present. '; desc30 = 'Case 4 - Figure 4 - Spindled and round tumour cell nuclei are enlarged. Note scattered mitotic figures (arrow). '; desc31 = 'Case 4 - Figure 5 - Hyalinisation of the tumour stroma. '; desc32 = 'Case 4 - Figure 6 - Immunohistochemically, tumour cells cells stain homogeneously positive for S-100 protein. '; desc33 = 'Case 4 - Figure 7 - The majority of neoplastic cells stains positively for HMB-45. '; desc34 = 'Case 4 - Figure 8 - Nuclear expression of MiTF1 is seen. '; desc35 = 'Case 4 - Figure 9 - Ki-67 antibodies reveal an increased proliferative activity of atypical tumour cells. '; desc36 = 'Case 4 - Figure 10 - Lymph node metastasis. Most of the lymphatic tissue is replaced by confluent nests and bundles composed of atypical fusiform tumour cells. '; desc37 = 'Case 4 - Figure 11 - Tumour cells stain positively for Melan-A. '; desc38 = 'Case 5 - Figure 1 - The lesion is located in deep dermis and subcutis. It has a nodular or plexiform pattern. '; desc39 = 'Case 5 - Figure 2 - Plexiform pattern with confluent and discrete tumor nodules extending into subcutaneous fat. '; desc40 = 'Case 5 - Figure 3 - Tumor is present within dermis and incorporates adnexa. '; desc41 = 'Case 5 - Figure 4 - At the deep aspect foci of tumor involve skeletal muscle. '; desc42 = 'Case 5 - Figure 5 - Tumor nodules in fat show peripheral fibrosis. '; desc43 = 'Case 5 - Figure 6 - The nodules comprise rounded mononuclear cells, bland spindle cells and an admixture of osteoclast-like giant cells, with focal fibrosis. '; desc44 = 'Case 5 - Figure 7 - Cells in tumor nodules show no pleomorphism or mitotic activity. There is a lymphocytic infiltrate. '; desc45 = 'Case 5 - Figure 8 - Some nodules manifest marked sclerosis or hyalinization with residual cellular component. '; descv01 = 'Case 1 - Slide 1 '; descv02 = 'Case 2 - Slide 1 '; descv03 = 'Case 3 - Slide 1 '; descv04 = 'Case 4 - Slide 1 '; descv05 = 'Case 5 - Slide 1 '; function parnav(imgnum) { parent.dir = '97th'; eval("parent.desc = desc"+imgnum); eval("parent.slidenum = 'bone"+imgnum+"'"); slidepop(); return; } function winstatus(imgnum) { eval("window.status = desc"+imgnum+";"); return; }