/* Sequence of slide descriptions */ desc01 = 'Case 1 - Figure 1 - Low power photomicrograph illustrating broad sheets of tumor infiltrating renal parenchyma. The tumor has delicate thin walled blood vessels. '; desc02 = 'Case 1 - Figure 2 - The tumor has a cystic component with many of the cysts containing serofibrinous fluid or blood. '; desc03 = 'Case 1 - Figure 3 - Highly cellular tumor infiltrates renal sinus fat. '; desc04 = 'Case 1 - Figure 4 - Tumor growing into proximal renal vein. Note tumor attachment to the renal vein wall. '; desc05 = 'Case 1 - Figure 5 - The tumor cells are haphazardly arrayed around cysts. '; desc06 = 'Case 1 - Figure 6 - Focally a vaguely nested pattern is identified. '; desc07 = 'Case 1 - Figure 7 - Focal necrosis is evident. '; desc08 = 'Case 1 - Figure 8 - Tumor cells are relatively monotonous with round to ovoid nuclei and a high nuclear to cytoplasmic ratio. Nuclei are vesicular with small or inconspicuous nucleoli. Mitotic figures are frequent. '; desc09 = 'Case 1 - Figure 9 - In some areas, tumor cells display, a small amount of pale cytoplasm. '; desc10 = 'Case 1 - Figure 10 - Focally nuclei are slightly more pleomorphic and hyperchromatic. '; desc11 = 'Case 1 - Figure 11 - CAM 5.2 immunostain reveals that occasional tumor cells are positive. '; desc12 = 'Case 2 - Figure 1 - Core biopsy with two solid epithelial areas '; desc13 = 'Case 2 - Figure 2 - Cribriform well out-line epithelial areas '; desc14 = 'Case 2 - Figure 3 - High magnification with secretory atypical cells in a cribriform fused gland pattern '; desc15 = 'Case 2 - Figure 4 - '; desc16 = 'Case 2 - Figure 4 - 34βE12 cytokeratin in both solid epithelial areas '; desc17 = 'Case 2 - Figure 5 - '; desc18 = 'Case 2 - Figure 5 - 34βE12 cytokeratin in both solid epithelial areas '; desc19 = 'Case 3 - Figure 1 - Low power view shows variable-sized glands infiltrating within the muscularis propria of the bladder. '; desc20 = 'Case 3 - Figure 2 - At high power view of figure 1, one gland in the center is lined by mucinous epithelium. '; desc21 = 'Case 3 - Figure 3 - Other small glands in figure 1 are tubular in shape and are lined by cuboidal to columnar nonmucinous cells. Although some nuclei have prominent nucleoli, no cytologic atypia is seen. Some glands also show nuclear stratification. '; desc22 = 'Case 3 - Figure 4 - Low power view of several glands within the muscularis propria in a different fragment: small tubular glands and two cystically dilated ones. '; desc23 = 'Case 3 - Figure 5 - The two cystically dilated glands in figure 4 are lined by one single layer of cuboidal cells with mucinous cytoplasm and bland nuclei. The tubular glands are lined by nonmucinous columnar cells (with some cautery effect). '; desc24 = 'Case 3 - Figure 6 - Another fragment contains multiple tubular glands and few cystically dilated glands that are infiltrating the muscularis propria of the bladder. '; desc25 = 'Case 3 - Figure 7 - Medium power view of the glands and their surrounding stroma of figure 6. '; desc26 = 'Case 3 - Figure 8 - Some glands in figures 6 contain subnuclear cytoplasmic vacuoles. The lining cells are stratified cuboidal to columnar cells. The surrounding stroma consists of spindled to epithelioid cells. There is some collagen within the stroma. '; desc43 = 'Case 3 - Figure 9 - The glands and their surrounding stromal cells seen in figures 6-8 are diffusely and strongly positive for estrogen receptor (ER). The smooth muscle cells of the muscularis propria of the bladder (left and right upper corners) are negative for ER. '; desc44 = 'Case 3 - Figure 10 - The glands and their surrounding stromal cells seen in figures 6-8 are diffusely and strongly positive for progesterone receptor (PR). The smooth muscle cells of the muscularis propria of the bladder (left and right upper corners) are negative for PR. '; desc45 = 'Case 3 - Figure 11 - The stroma cells surrounding the glands seen in figures 6-8 are diffusely positive for CD10. The smooth muscle cells of the muscularis propria of the bladder (left and right upper corners) are negative for CD10. '; desc27 = 'Case 4 - Figure 1 - Gross appearance of the 2.0 cm enucleated testicular mass. '; desc28 = 'Case 4 - Figure 2 - Low magnification view of the lesion. '; desc29 = 'Case 4 - Figure 3 - Two views of the mesenchymal component of the lesion. The image on the left contains primitive-appearing stromal cells and the image on the left appears more fibrous. '; desc30 = 'Case 4 - Figure 4 - Cells forming cords and nests in a fibrous stroma. '; desc31 = 'Case 4 - Figure 5 - Single cells infiltrating a fibrous stroma. '; desc32 = 'Case 4 - Figure 6 - Two tubular structures contain densely eosinophilic hyaline bodies. '; desc33 = 'Case 4 - Figure 7 - Immunohistochemical stain for Inhibin '; desc34 = 'Case 4 - Figure 8 - Immunohistochemical stain for estrogen receptor. '; desc35 = 'Case 5 - Figure 1 - Primary enteric-type adenocarcinoma of the urethra appearing as a polypoid glandular proliferation. Notice the benign-appearing orderly and villous glandular pattern near the top. '; desc36 = 'Case 5 - Figure 2 - The tumor is composed of a complex glandular proliferation in which abundant dirty necrosis is evident. The appearances are clearly identical to what is seen in invasive colonic adenocarcinoma. '; desc37 = 'Case 5 - Figure 3 - Enteric-type adenocarcinoma displaying stratified columnar cells with elongated nuclei. Abundant mitotic activity is present. '; desc38 = 'Case 5 - Figure 4 - A high power magnification shows a malignant gland with dirty necrosis. '; desc39 = 'Case 5 - Figure 5 - Other areas of the tumor showed a prominent cribriform architecture also reminiscent of colonic adenocarcinoma. '; desc40 = 'Case 5 - Figure 6 - In this figure, adenocarcinomatous epithelium is seen within and distorting a von Brunn nest. This could represent adenocarcinoma in-situ, or more likely, extension of adenocarcinoma into von Brunn nests in the manner usually seen with urothelial carcinomas. '; desc41 = 'Case 5 - Figure 7 - The tumor was diffusely positive for CDX2. The tumor was also positive for villin (not shown) and displayed a nuclear staining pattern for beta-catenin (not shown). '; desc42 = 'Case 5 - Figure 8 - The tumor was also positive for cytokeratin 20 but negative for cytokeratin 7 (not shown). '; descv01 = 'Case 1 - Slide 1 '; descv02 = 'Case 2 - Slide 1 '; descv03 = 'Case 3 - Slide 1 '; descv04 = 'Case 4 - Slide 1 '; descv05 = 'Case 5 - Slide 1 '; function parnav(imgnum) { parent.dir = '97th'; eval("parent.desc = desc"+imgnum); eval("parent.slidenum = 'geni"+imgnum+"'"); slidepop(); return; } function winstatus(imgnum) { eval("window.status = desc"+imgnum+";"); return; }