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Tuesday, March 4, 2008 — 8:00 AM - 1:00 PM
Convention Center 108/110/112
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COURSE DIRECTORS:
Frederic G. Barr, M.D., Ph.D.
University of Pennsylvania
Philadelphia, PA
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This special course will provide an in-depth consideration of recent advances in molecular biology and genetics that are enhancing the understanding of the pathogenesis of human cancer and other diseases, and impacting on the practice of diagnostic pathology. Topics will be chosen to highlight specific advances in the field of cancer, with considerations of molecular mechanisms of tumorigenesis, the role of basic genetic and biochemical signaling pathways, the impact of microbiology and developmental biology, and a variety of methodologic approaches. The program is designed as an update for both practicing pathologists and primary investigators on these specific topics as well as general trends in the field of molecular pathology. In addition to presenting a basic scientific foundation on each topic, each lecture will provide practical information concerning how this information can be applied in diagnostic and therapeutic settings. Therefore, an important overall emphasis of this course will be translational issues that link basic discoveries with the practice of pathology.
AGENDA
| 8:00 | Introduction
Frederick G. Barr, M.D., Ph.D. |
| 8:10 | Molecular pathogenesis of H. pylori-associated diseases: the stomach and beyond
Antonia R. Sepulveda MD., Ph.D., University of Pennsylvania School of Medicine, Philadelphia, PA |
| 8:55 | Molecular mechanisms of chromosomal translocation
Michael R. Lieber, M.D., Ph.D., Univ.y of Southern California, Los Angeles, CA |
| 9:40 | Development of innovative preventive and therapeutic HPV vaccines-post Gardasil Era
T.-C. Wu, M.D., Ph.D., The Johns Hopkins Medical Institutions, Baltimore MD |
| 10:25 | Break (Coffee available in Exhibit Hall A) |
| 10:45 | Mass spectrometry as a driver of discovery in lymphoma pathogenesis
Kojo S. J. Elenitoba-Johnson, M.D., University of Michigan Medical School, Ann Arbor,MI |
| 11:30 | The PI 3-Kinase and Akt signaling pathway in cancer progression
Alex Toker, PhD, Beth Israel Deaconess Medical Center, Boston, MA |
| 12:15 | The Cancer Genome Atlas and other large scale cancer genomics projects: "big science" meets cancer molecular pathology
Marc Ladanyi, M.D., Memorial Sloan-Kettering Cancer Center, New York, NY |
| 1:00 | Concluding Remarks and Question Period |
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