/* Sequence of slide descriptions */ desc01 = 'Case 1 - Figure 1 - T1-weighted MRI showing bilateral contrast-enhancing dural-based masses. '; desc02 = 'Case 1 - Figure 2 - Low magnification H&E-stained section showing a cellular lesion attached to the dura mater (lower left). '; desc03 = 'Case 1 - Figure 3 - Intermediate magnification H&E-stained section showing a mixed inflammatory infiltrate composed of mature lymphocytes (left), plasma cells (right), and histiocyte-like cells. '; desc04 = 'Case 1 - Figure 4 - High magnification H&E-stained section showing a prominent plasma cell infiltrate (right) and atypical histiocyte-like cells with large nuclei and prominent nucleoli. '; desc05 = 'Case 1 - Figure 5 - High magnification H&E-stained section showing atypical histiocyte-like cells with large nuclei and prominent nucleoli in a background of mature lymphocytes. '; desc06 = 'Case 1 - Figure 6 - High magnification H&E-stained section showing an atypical histiocyte-like cell that contains several engulfed mononuclear cells. '; desc07 = 'Case 1 - Figure 7 - Immunohistochemical reaction for S-100 (high magnification) showing strongly reactive histiocytes with engulfed mononuclear cells. '; desc08 = 'Case 1 - Figure 8 - Immunohistochemical reaction for CD68 (high magnification) showing positive reactivity of histiocytic cells. '; desc09 = 'Case 2 - Figure 1 - Sagittal T1-weighted, contrast-enhanced MRI of the cervical spine shows a lesion at the level of the foramen magnum. '; desc10 = 'Case 2 - Figure 2 - Sagittal T2-weighted MRI of the cervical spine shows the foramen magnum lesion. '; desc11 = 'Case 2 - Figure 3 - Axial T2-weighted image showing mass effect on the upper cervical spinal cord. '; desc12 = 'Case 2 - Figure 4 - The lesion exhibited multiple lobules with a hypocellular chondromyxoid matrix and a granulomatous-like appearance rimmed by palisading spindled/round cells (H&E x 4). '; desc13 = 'Case 2 - Figure 5 - Higher magnification showing the hypocellular lobules rimmed by spindled cells (H&E x 20). '; desc14 = 'Case 2 - Figure 6 - Areas of the lesion were ossified and calcified and showed a deeply basophilic appearance (H&E x 10). '; desc15 = 'Case 2 - Figure 7 - High magnification showing coarse fibrillar basophilic material within the nodules and surrounded by spindled cells (H&E x 40). '; desc16 = 'Case 2 - Figure 8 - Alcian blue histochemical stain shows positive staining of the matrix within the lobules. '; desc17 = 'Case 2 - Figure 9 - Adjacent to some of the lobules were proliferations of spindled cells with occasional whorl structures among numerous blood vessels (H&E x 40). '; desc18 = 'Case 2 - Figure 10 - An epithelial membrane antigen immunohistochemical stain highlights the spindle '; desc19 = 'Case 3 - Figure 1 - MRI coronal section showing ring-enhancing temporal lesion abutting dura '; desc20 = 'Case 3 - Figure 2 - Cytologic touch imprint preparation showing hypercellularity and nuclear pleomorphism '; desc21 = 'Case 3 - Figure 3 - medium power: glial component with vascular proliferation and necrosis '; desc22 = 'Case 3 - Figure 4 - medium power: small cell component with focal multinucleated cells '; desc23 = 'Case 3 - Figure 5 - medium power: small cell component with mitotic activity '; desc24 = 'Case 3 - Figure 6 - low power: small cell component and adjacent gliotic brain tissue '; desc25 = 'Case 3 - Figure 7 - low power: GFAP negative tumor cells with occasional reactive astrocytes within and in adjacent gliotic brain tissue '; desc26 = 'Case 3 - Figure 8 - low power: Synaptophysin positive neoplastic small cells '; desc27 = 'Case 3 - Figure 9 - high power: marked nuclear pleomorphism in large apparently glial cells with mitoses '; desc28 = 'Case 3 - Figure 10 - high power: GFAP immunoreactive large pleomorphic cells '; desc29 = 'Case 3 - Figure 11 - high power: Synaptophysin immunoreactive large multinucleated neoplastic cells '; desc30 = 'Case 4 - Figure 1 - Neuroimaging study of the lesions '; desc31 = 'Case 4 - Figure 2 - Low power photomicrograph of the well-demarcated lesion, 4X '; desc32 = 'Case 4 - Figure 3 - Medium power photomicrographs illustrating features of the lesion, 10X. '; desc33 = 'Case 4 - Figure 4 - Medium power photomicrographs illustrating features of the lesion, 10X. '; desc34 = 'Case 4 - Figure 5 - Medium power photomicrographs illustrating features of the lesion, 10X. '; desc35 = 'Case 4 - Figure 6 - Reticulin stain at interface between lesion (right) and brain (left), 20X '; desc36 = 'Case 4 - Figure 7 - Trichrome stain at interface between lesion (left) and brain (right), 20X. Note Rosenthal fiber (red). '; desc37 = 'Case 5 - Figure 1 - a,b - Axial fluid attenuated inversion recovery (FLAIR) and T2-weighted images showing a hyperintense mass in the left frontal lobe with no significant mass effect or peritumoral edema. '; desc38 = 'Case 5 - Figure 2 - a,b - Axial pre- and post-contrast T1-weighted images showing a mass that is slightly hypointense to gray matter with no appreciable enhancement. '; desc39 = 'Case 5 - Figure 3 - a,b - Coronal T2-weighted and post-contrast T1-weighted images showing the extent of tumor in the left frontal lobe and a small focus of enhancement in the inferior aspect of the mass. '; desc40 = 'Case 5 - Figure 4 - a,b - MR perfusion image and graphic representation of perfusion in two selected regions of tumor (1,3) and two regions of normal-appearing parenchyma in the contralateral hemisphere (2,4). '; desc41 = 'Case 5 - Figure 5 - a,b,c - Postoperative axial pre-contrast T1, FLAIR, and post-contrast T1-weighted images showing no appreciable residual signal attributable to residual tumor. '; desc42 = 'Case 5 - Figure 6 - a,b - Postoperative FLAIR and diffusion-weighted images showing a narrow rim of diffusion abnormality around the resection cavity. '; desc43 = 'Case 5 - Figure 7 - Medium power H&E image of one tumor component showing a rather monotonous population of cells. '; desc44 = 'Case 5 - Figure 8 - Higher power H&E image of the monotonous population showing "fried-egg" (perinuclear halo) cells and delicate vasculature. '; desc45 = 'Case 5 - Figure 9 - Medium power H&E image of another area of the tumor showing a more pleomorphic population of cells and delicate hypervascularity. '; desc46 = 'Case 5 - Figure 10 - Medium-high power H&E image of the second tumor pattern showing only rare cells with a "fried-egg" appearance and delicate vascular background. '; desc47 = 'Case 5 - Figure 11 - High power H&E image of a third morphologic pattern within the tumor showing a population of pleomorphic cells that exhibit elongated and irregular nuclei with hyperchromasia. '; desc48 = 'Case 5 - Figure 12 - High power H&E image of the third pattern highlighting the nuclear and chromatin structure of the cells. '; descv01 = 'Case 1 - Slide 1 '; descv02 = 'Case 2 - Slide 1 '; descv03 = 'Case 3 - Slide 1 '; descv04 = 'Case 4 - Slide 1 '; descv05 = 'Case 5 - Slide 1 '; descv06 = 'Case 5 - Slide 2 '; function parnav(imgnum) { parent.dir = '97th'; eval("parent.desc = desc"+imgnum); eval("parent.slidenum = 'neur"+imgnum+"'"); slidepop(); return; } function winstatus(imgnum) { eval("window.status = desc"+imgnum+";"); return; }