CPAM Type 2 with Striated Muscle Cells
Aliya N. Husain
University of Chicago
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Clinical History
On prenatal ultrasound, this baby boy was found to have a left lung sequestration/mass. There was no other malformation seen. The lesion was resected at 8 weeks of age. The specimen consisted of tan-pink tissue measuring 3.3 x 2.6 x 1.7 cm. Serial sectioning showed multiple cysts varying in size from 0.1 to 0.5 cm.
Case 5 - Figure 1 Low power view of lung section showing bronchus in the lower part and cystic structures in the upper part.
Case 5 - Figure 2 Medium power photomicrograph of bronchus and cysts, No alveolated lung is seen.
Case 5 - Figure 3 Low power view of peripheral lung completely replaced by small to intermediate sized cysts.
Case 5 - Figure 4 High power of cysts showing ciliated columnar epithelial lining. No smooth muscle or mucogenic cells are present in the cyst wall. The intervening fibrovascular stroma contains pink cells.
Case 5 - Figure 5 Highest power photomicrograph shows skeletal muscle cells with cross striations within the stroma between the cysts.
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