CPAM Type 2 with Striated Muscle Cells Aliya N. Husain University of Chicago

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Click here to view (or print) handout in single page format. (1.27 MB) Note: Any slides will be printed in color. Click here to view (or print) black and white handout. (1.30 MB) Note: Text will be in single page format and any slides will be in 6-per-page format. Clinical History On prenatal ultrasound, this baby boy was found to have a left lung sequestration/mass. There was no other malformation seen. The lesion was resected at 8 weeks of age. The specimen consisted of tan-pink tissue measuring 3.3 x 2.6 x 1.7 cm. Serial sectioning showed multiple cysts varying in size from 0.1 to 0.5 cm. Slide 1 Click to view with ImageScope Click to view with a Web-Based Viewer Figure 1 Low power view of lung section showing bronchus in the lower part and cystic structures in the upper part. Figure 2 Medium power photomicrograph of bronchus and cysts, No alveolated lung is seen. Figure 3 Low power view of peripheral lung completely replaced by small to intermediate sized cysts. Figure 4 High power of cysts showing ciliated columnar epithelial lining. No smooth muscle or mucogenic cells are present in the cyst wall. The intervening fibrovascular stroma contains pink cells. Figure 5 Highest power photomicrograph shows skeletal muscle cells with cross striations within the stroma between the cysts.