/* Sequence of slide descriptions */ desc01 = 'Case 1 - Figure 1 - 10x. Portal area upper right, central zonal scar on left, and extensive intrasinusoidal scarring is also present. Inflammation is scant, and ductular reaction is present in lobular zone 1. (10x) '; desc02 = 'Case 1 - Figure 2 - Higher magnification (20x). The scar at the bottom of the photo is the residual centrizonal region (zone 3). Ductular metaplasia is present in zone 1 and 2, and ballooned hepatocytes are present near the centrizonal scar. Mild large droplet fat is present. '; desc03 = 'Case 1 - Figure 3 - 40x. Ballooned hepatocytes and ductular metaplasia. Also note the sinusoidal pattern of scarring. Inflammation is mostly mononuclear but some neutrophils are also present. Focal large droplet fat is present on right. '; desc04 = 'Case 1 - Figure 4 - 20x. Similar to figure 3, with ballooned hepatocytes, ductular metaplasia. The inflammatory infiltrate is more mixed than in fig 3. Mallory hyaline is present in ballooned hepatocytes (center, bottom center and bottom right). '; desc05 = 'Case 1 - Figure 5 - 20x. Prominent ballooned hepatocytes, many which contain Mallory hyaline. Also note bile stasis/bile plugs. Metaplastic ductule is present on left. '; desc06 = 'Case 1 - Figure 6 - 20x. Prominent ballooned hepatocytes, many with Mallory hyaline. Fatty change is scant but present. '; desc07 = 'Case 1 - Figure 7 - 40x. Centrizonal scar, with adjacent ballooned hepatocyte that contains prominent Mallory hyaline. '; desc08 = 'Case 1 - Figure 8 - 40x. Zone of prominent cholestasis. Large droplet fat is also present. Note sinusoidal fibrosis. '; desc09 = 'Case 1 - Figure 9 - Trichrome stain, 10x. Portal zone at bottom, centrizonal scar at top center. Note sinusoidal/centrizonal pattern of scarring. Fatty change can be identified. '; desc10 = 'Case 1 - Figure 10 - Trichrome stain, 10x. Portal zone on left, residual centrizonal area with scar on right. Sinusoidal and centrizonal pattern of scarring is prominent. '; desc11 = 'Case 1 - Figure 11 - Trichrome stain, 20x. Central vein with surrounding scar. Pericellular and sinusoidal scarring is prominent. '; desc12 = 'Case 1 - Figure 12 - Orcein stain, 20x. Central vein wall is outlined by the dark fibers in the center. The lumen of the vein is sclerosed and occluded. '; desc13 = 'Case 2 - Figure 1 - Scanning magnification shows a dome-shaped lesion in the skin . '; desc14 = 'Case 2 - Figure 2 - At low magnification, thickened collagen bundles and increased cellularity can be appreciated. '; desc15 = 'Case 2 - Figure 3 - The lesion extends through much of the thickness of the reticular dermis. '; desc16 = 'Case 2 - Figure 4 - The lesion is comprised of uniform cells placed among thickened collagen bundles. '; desc17 = 'Case 2 - Figure 5 - The lesional cells are plump spindle cells. A prominent vascular stroma is also appreciated. '; desc18 = 'Case 2 - Figure 6 - At higher magnification prominent relatively thick walled vessels are present in association with the infiltrating spindle cells and the thickened collagen bundles. '; desc19 = 'Case 2 - Figure 7 - Plump spindle cells infiltrating among thick collagen fibers at the base of the lesion. '; desc20 = 'Case 2 - Figure 8 - In another area near the base, lesional cells infiltrate as single cells among more normal collagen fiber bundles. In the upper left, one of the thick walled vessels with plump endothelial cells is appreciated. '; desc21 = 'Case 2 - Figure 9 - S-100 - An S100 stain demonstrates strong and diffuse uniform positivity throughout the lesion. '; desc22 = 'Case 2 - Figure 10 - S-100 - The plump spindle cells are uniformly and strongly S100 positive. '; desc23 = 'Case 2 - Figure 11 - HMB45 - An HMB45 stain demonstrates a rare group of positive cells in the superficial portion of the lesion. '; desc24 = 'Case 2 - Figure 12 - HMB45 - The positive cells are strongly stained. A few cells containing pigment, mostly melanophages, are also present along with a sprinkling of lymphocytes. '; desc25 = 'Case 2 - Figure 13 - Actin - An actin stain highlights the vessels which are present throughout the profile of the tumor. Contrast this increased vascularity with the normal vascularity of the adjacent uninvolved reticular dermis. '; desc26 = 'Case 2 - Figure 14 - Actin - The actin strongly stains vessel walls, indicating the presence of pericytes. '; desc27 = 'Case 2 - Figure 15 - FVIIIRAg - A stain for factor VIII highlights the thickened endothelial cells. '; desc28 = 'Case 3 - Figure 1 '; desc29 = 'Case 3 - Figure 2 '; desc30 = 'Case 3 - Figure 3 '; desc31 = 'Case 3 - Figure 4 - Low and high magnification views of a duct space showing effacement of the normal epithelium by a population of atypical cells arranged in a micropapillary configuration. The features are typical of low to intermediate grade DCIS. '; desc32 = 'Case 3 - Figure 5 - Low and high magnification views of a duct spaces an admixture of DCIS with islands of paler cells with the morphology of lobular neoplasia (LCIS). '; desc33 = 'Case 3 - Figure 6 - Low and high magnification views of a duct spaces an admixture of DCIS with islands of paler cells with the morphology of lobular neoplasia (LCIS). '; desc34 = 'Case 3 - Figure 7 - An expanded lobule adjacent to the tissue illustrated in figure 1-6 showing features typical of lobular carcinoma in situ. '; desc35 = 'Case 3 - Figure 8 - More examples of intimately admixed DCIS and LCIS. '; desc36 = 'Case 3 - Figure 9 - More examples of intimately admixed DCIS and LCIS. '; desc37 = 'Case 3 - Figure 10 - E-Cadherin immunocytochemistry staining shows strong membrane positive reactivity in the DCIS component and negativity in the LCIS component in the pure and admixed areas. '; desc38 = 'Case 3 - Figure 11 - E-Cadherin immunocytochemistry staining shows strong membrane positive reactivity in the DCIS component and negativity in the LCIS component in the pure and admixed areas. '; desc39 = 'Case 3 - Figure 12 - E-Cadherin immunocytochemistry staining shows strong membrane positive reactivity in the DCIS component and negativity in the LCIS component in the pure and admixed areas. '; desc40 = 'Case 4 - Figure 1 - The paratesticular ectomesenchymoma shows a proliferation of spindle and polygonal cells in sheets and fascicles. '; desc41 = 'Case 4 - Figure 2 - The spindle cells are embedded in a myxoid and collagenized background and have elongated eosinophilic cytoplasmic extensions. '; desc42 = 'Case 4 - Figure 3 - Mature ganglion cells with eosinophilic cytoplasm are intermingled with spindle cells. '; desc43 = 'Case 4 - Figure 4 - The spindle cells have oval to elongated nuclei with granular chromatin, occasional prominent nucleoli and variable amounts of eosinophilic cytoplasm, with a focal strap-like configuration. '; desc44 = 'Case 4 - Figure 5 - The mature ganglion cells are intermingled with spindle cells and in some areas the background resembles neuropil. '; desc45 = 'Case 4 - Figure 6 - MYOGENIN - Diffuse nuclear reactivity for myogenin is present in areas of rhabdomyoblastic differentiation. '; desc46 = 'Case 4 - Figure 7 - DESMIN - Diffuse cytoplasmic reactivity for desmin is present in areas of rhabdomyoblastic differentiation. '; desc47 = 'Case 4 - Figure 8 - SYNAPTOPHYSIN - Cytoplasmic reactivity for synaptophysin is present in ganglion cells '; desc48 = 'Case 5 - Figure 1 - Low magnification showing the presence of a well-circumscribed follicular epithelial cell lesion. '; desc49 = 'Case 5 - Figure 2 - Slightly higher magnification showing the well-circumscribed follicular epithelial cell lesion within which are scattered areas of apparent increased cellularity. '; desc50 = 'Case 5 - Figure 3 - At higher magnification, areas of this lesion show round and regular appearing nuclei with coarse nuclear chromatin. '; desc51 = 'Case 5 - Figure 4 - At higher magnification, areas of this lesion show round and regular appearing nuclei with coarse nuclear chromatin. '; desc52 = 'Case 5 - Figure 5 - At higher magnification, areas of this lesion show the presence of enlarged nuclei with irregularities in size and shape, dispersed to optical clear appearing nuclear chromatin, nuclear crowding and overlapping, and nuclear grooves. '; desc53 = 'Case 5 - Figure 6 - At higher magnification, areas of this lesion show the presence of enlarged nuclei with irregularities in size and shape, dispersed to optical clear appearing nuclear chromatin, nuclear crowding and overlapping, and nuclear grooves. '; descv01 = 'Case 1 - Slide 1'; descv02 = 'Case 2 - Slide 1'; descv03 = 'Case 3 - Slide 1'; descv04 = 'Case 4 - Slide 1'; descv05 = 'Case 5 - Slide 1'; function parnav(imgnum) { parent.dir = '97th'; eval("parent.desc = desc"+imgnum); eval("parent.slidenum = 'surg"+imgnum+"'"); slidepop(); return; } function winstatus(imgnum) { eval("window.status = desc"+imgnum+";"); return; }