Case 2 -

Metastatic Poorly Differentiated Endometrioid Adenocarcinoma Arising in Adenomyosis Lora Hedrick Ellenson Weill Medical College of Cornell University New York, NY

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Click here to download handout in 1-up pdf format for the current section (16.7 MB) Click here to download handout in 6-up pdf format for the current section (1.47 MB) Clinical History: 35-year-old G0 woman with a unilateral adnexal cystic mass. Case 2 - Slide 1 Click to view with ImageScope Click to view with a Web-Based Viewer Case 2 - Figure 1 Case 2 - Figure 2 Case 2 - Figure 3 Case 2 - Figure 4 Case 2 - Figure 5 Mucicarmine Case 2 - Figure 6 CK7 Case 2 - Figure 7 CK20 Case 2 - Figure 8 ER Case 2 - Figure 9 PR Case 2 - Figure 10 WT-1 Differential Diagnosis: Metastatic gastric carcinoma Poorly differentiated carcinoma of the ovary Metastatic endometrial carcinoma Final Diagnosis: Metastatic poorly differentiated endometrioid adenocarcinoma arising in adenomyosis References: Molecular, pathologic, and clinical features of early-onset endometrial cancer: identifying presumptive Lynch syndrome patients. Walsh MD et al. Clin Cancer Res. 2008 March 15; 4(6):1692-700. Microsatellite instability and epigenetic inactivation of MLH1 and outcome of patients with endometrial carcinomas of the endometrioid type. Zighelboim I et al. J Clin Oncol. 2007 May 20; 25(15):2042-8. Utility of immunohistochemistry in predicting microsatellite instability in endometrial carcinoma. Modica I et al. Am J Surg Pathol. 2007 May; 31(5):744-51. Body mass index: relationship to clinical, pathological and features of microsatellite instability in endometrial cancer. McCourt CK et al. Gynecol Oncol. 2007 Mar;104(3):535-9.