XXVI International Congress of the International Academy of Pathology Montreal, Quebec, Canada Slide Seminar 06 - Value of Immunohistochemistry in Gynecological Pathology Monday, September 18, 2006 08:00 - 12:00   Moderator: Dr. W. Glenn McCluggage   Disclosure: In accordance with ACCME guidelines regarding disclosure, the USCAP policy requires that faculty members who have a significant financial or other relationship with a commercial company, entity, or service (which will be discussed in this Slide Seminar) must disclose this to attendees. The Academy also requires that speakers disclose any products that are not labeled for the use under discussion. Faculty members for this Slide Seminar have indicated they have no disclosures to make. Clinical histories are displayed below. Click on the case numbers to display the text and references for each case. Click on each slide thumbnail image to view each slide in a Web-based slide viewer. Windows users with administrator privileges may download and install a free version of Aperio ImageScope to view USCAP Virtual Slides. Click the icon on the right to get your free copy:   Case 1 - Ovarian Paraganglioma Submitted by: Dr. W. Glenn McCluggage Clinical History: 22cm solid yellow/brown ovarian tumour. Case 1 - Figure 1 Click to view with ImageScope Click to view with a Web-Based Viewer Case 2 - Ovarian Serous Cystadenofibroma with Stromal Sex Cord Elements Submitted by: Dr. W. Glenn McCluggage Clinical History: 40 cm mainly cystic ovarian tumour. Case 2 - Figure 1 Click to view with ImageScope Click to view with a Web-Based Viewer Case 3 - Primary Endometrioid Adenocarcinoma of the Ovary vs. Metastatic Endocervical Adenocarcinoma to the Ovary Submitted by: Charles Zaloudek, M.D. Clinical History: Previous hysterectomy. 29 cm left ovarian mass, partially cystic and partially solid, removed. Case 3 - Figure 1 Click to view with ImageScope Click to view with a Web-Based Viewer Case 4 - Dysgerminoma vs. Poorly Differentiated Carcinoma Submitted by: Charles Zaloudek, M.D. Clinical History: 9 cm solid ovarian mass with areas of cystic degeneration. Case 4 - Figure 1 Click to view with ImageScope Click to view with a Web-Based Viewer Case 5 - Gastrointestinal Stromal Tumor Metastatic to the Ovary Submitted by: Julie A. Irving, MD, FRCPC Clinical History: 10.5 cm unilateral solid ovarian mass. Case 5 - Figure 1 Click to view with ImageScope Click to view with a Web-Based Viewer Case 6 - Lung Adenocarcinoma, Mixed Papillary-acinar Type, Metastatic to the Ovary Submitted by: Julie A. Irving, MD, FRCPC Clinical History: 15 cm unilateral solid/cystic ovarian mass. Previous hysterectomy for cervical cancer. Case 6 - Figure 1 Click to view with ImageScope Click to view with a Web-Based Viewer Case 7 - Vulvar Squamous Cell Carcinoma, Keratinizing Type, HPV Related Submitted by: Dr. Jaume Ordi Clinical History: 2 cm exophytic vulval tumour with peri-clitoral location. Case 7 - Figure 1 Click to view with ImageScope Click to view with a Web-Based Viewer Case 8 - Endometrial Carcinoma Grade 1 with Squamous Metaplasia Involving the Lower Uterine Segment Submitted by: Dr. Jaume Ordi, Clinical History: Postmenopausal bleeding. Endometrial curettage showed carcinoma. Hysterectomy and bilateral salpingo-oophorectomy. Section includes lower uterine segment and endocervical canal. Case 8 - Figure 1 Click to view with ImageScope Click to view with a Web-Based Viewer Case 9 - Thyroid Transcription Factor-1 (TTF-1) Submitted by: Michael T. Deavers, M.D. Clinical History: Previous TAH and BSO for endometrial carcinoma (slide provided). Now multiple pulmonary metastases. Case 9 - Figure 1 Click to view with ImageScope Click to view with a Web-Based Viewer Case 10 - Leiomyosarcoma Submitted by: Michael T. Deavers, M.D. Clinical History: Presented with shortness of breath. CT of chest showed multiple pulmonary and pleural nodules. Lytic lesion in femur which was resected (slide provided). Case 10 - Figure 1 Click to view with ImageScope Click to view with a Web-Based Viewer Case 11 - Cervical Embryonal Rhabdomyosarcoma Submitted by: Dr. Robert Soslow Clinical History: Vaginal bleeding. Polypoid lesion protruding through cervical os. Biopsy followed by hysterectomy. Case 11 - Figure 1 Click to view with ImageScope Click to view with a Web-Based Viewer Case 12 - Extra-axial Ependymoma Submitted by: Dr. Robert Soslow Clinical History: Diagnosis of ovarian serous carcinoma 12 years previously. Had unilateral salpingo-oophorectomy followed by chemotherapy. Recurrent disease. Case 12 - Figure 1 Click to view with ImageScope Click to view with a Web-Based Viewer