XXVI International Congress of the
International Academy of Pathology
Montreal, Quebec, Canada




Slide Seminar 14 - Bone Pathology

Tuesday, September 19, 2006 14:00 - 17:30




  Moderators: Dr. K. Krishnan Unni and Dr. Franco Bertoni
  Disclosure: In accordance with ACCME guidelines regarding disclosure, the USCAP policy requires that faculty members who have a significant financial or other relationship with a commercial company, entity, or service (which will be discussed in this Slide Seminar) must disclose this to attendees. The Academy also requires that speakers disclose any products that are not labeled for the use under discussion. Faculty members for this Slide Seminar have indicated they have no disclosures to make.



Clinical histories are displayed below.
Click on the case numbers to display the text and references for each case.
Click on each slide thumbnail image to view each slide in a Web-based slide viewer.
Windows users with administrator privileges may download and install a free version of Aperio ImageScope to view USCAP Virtual Slides. Click the icon on the right to get your free copy: 



Case 1 - Aneurysmal Bone Cyst

Submitted by: Dr. Carrie Inwards

Clinical History:

A 17 year old male complained of 5 months of back pain.


Case 1 - Slide 1
Click to view with ImageScope
Click to view with a Web-Based Viewer



Case 2 - Giant Cell Tumor with Osteogenesis

Submitted by: Dr. Patrizia Bacchini

Clinical History:

A 40 y.o. man with right sacro-iliac pain, two years duration. On april 2005, on x-rays a right iliac wing lytic lesion was detected.

A biopsy was performed.

The HE slide is from the incisional biopsy.


Case 2 - Slide 1
Click to view with ImageScope
Click to view with a Web-Based Viewer



Case 3 - Bone, Ilium, Right, Biopsy: Malignant Lymphoma, Hodgkin Lymphoma, Nodular Sclerosis

Submitted by: Dr. Yasuaki Nakashima

Clinical History:

Twenty-four years old, female with noted pain in the right flank to right hip, and consulted a local practitioner. On laboratory tests, however, no abnormal findings were found. Six months later, elevated erythrocyte sedimentation rate was detected. Because of radiating pain from her right hip, through the right lower extremity, to the right toe, she consulted an orthopedic surgeon and an osteolytic lesion in the right ilium was identified. She also noted fever of 38 centigrade. Five months later, about one year after the onset of her initial symptom of pain in the right flank, she underwent biopsy of the lesion in the right ilium.


Case 3 - Slide 1
Click to view with ImageScope
Click to view with a Web-Based Viewer



Case 4 - Tuberculosis of Knee

Submitted by: Dr. Nirmala Jambhekar

Clinical History:

28 year old male history of pain in the right knee region for the past four months


Case 4 - Slide 1
Click to view with ImageScope
Click to view with a Web-Based Viewer



Case 5 - Oncogenic Osteomalacia

Submitted by: Dr. Yong-koo Park

Clinical History:

The patient is a b47-year-old man suffering from low back pain and lower extremity weakness for 2 years. Before visiting this hospital, he visited another hospital and took a bone scan and it revealed multiple hot uptakes on the both ribs, hip, tibia and right femur neck. Simple x-ray of the right femur showed osteolytic lucent lesion at the diaphysis and also showed cortical thinning. His blood chemistry revealed slightly lower serum calcium (10.6 mg/dl) and phosphorus (1.2 mg/dl) and high alkaline phosphatase activity (303U/L).

Curettage was done on the right femoral diaphyseal lesion.


Case 5 - Slide 1
Click to view with ImageScope
Click to view with a Web-Based Viewer