Case 4 -

Juvenile polyposis with 'atypical juvenile polyps' and focal dysplasia Neil Shepherd

Case History: This 40 year old man had multiple polyps in his colon and rectum. These three polyps were snare resected from the sigmoid colon. Case 4 - Slide 1 Click to view with ImageScope Click to view with a Web-Based Viewer These odd-appearing polyps show the rather characteristic features of "atypical juvenile polyps". Although there is some surface ulceration, these polyps lack the widespread ulceration characteristic of standard juvenile polyps and they also show this rather papillary and multinodular appearance. There is undoubted dysplasia in some of these polyps. Such polyps are characteristic of juvenile polyposis. One of the small polyps appears uniformly dysplastic and some might regard this as an adenoma. References Jass JR, Williams CB, Bussey HJ, Morson BC. Juvenile polyposis - a precancerous condition. Histopathology 1988; 13: 619-30. Shepherd NA. Polyps and polyposis syndromes of the intestines. In Current Diagnostic Pathology, (ed Henry K), Churchill Livingstone, Edinburgh 1997; 222-238.