2015 Annual Meeting

SC21-Important Aspects of Skin Adnexal Tumor Pathology

2015 Annual Meeting

Room CC 309, March 26 2015, 1:00pm to 4:30pm

Thomas Brenn, Alexander Lazar, Melissa P. Pulitzer, Jaime E. Calonje

Educational Objective

The diagnosis and classification of skin adnexal tumors is notoriously difficult even to the experienced pathologist. This is largely due to the wide morphological spectrum of these neoplasms often showing only subtle differentiating features. This practical course aims to provide an overview of the important aspects of skin adnexal tumor pathology with emphasis on recently published findings and molecular developments. There will be a particular focus on diagnostic pitfalls, morphological clues to the correct diagnosis, appropriate use and interpretation of immunohistochemistry and clinical relevance. This course is suitable for a wide audience and may be particularly beneficial to senior residents, fellows in dermatopathology, and general surgical pathologists and dermatopathologists in practice. The course will be structured as a series of case presentations leading into a more structured discussion of tumors with sweat gland, sebaceous and hair follicle differentiation as well as Merkel cell carcinoma. The individual cases will be made available to the participants ahead of the course as virtual glass slides on the USCAP website to allow for self-study and self-assessment. Upon completion of the course, the participants will be familiar with the important clinical and diagnostic issues concerning skin adnexal tumors. They will be more confident in rendering definitive diagnoses and understand the implications on patient management. A syllabus containing the printed version of the presentation will be available prior to the meeting. After the meeting, all course registrants will also have access to the PowerPoint presentation on the USCAP website. Upon completion of this educational activity, participants should be able to:

  1. Increase awareness of the morphological spectrum of skin adnexal tumors;
  2. Emphasize diagnostic pitfalls and the subtle morphological clues to the correct diagnosis allowing distinction of benign from malignant skin adnexal tumors and separation form cutaneous metastasis of visceral primaries;
  3. Understand the value of immunohistochemistry and molecular diagnostics in the diagnosis of skin adnexal tumors;
  4. Recognize the implications of skin adnexal tumors that may be associated with inherited tumor predisposition syndromes
  5. Discuss recently identified tumor viruses.

Session Credits: CME = 3 / SAMs = N/A


SC Speaker
Speaker: Thomas Brenn, MD, Western General Hospital, Edinburgh, Scotsland
Access to Handouts
SC Speaker
Speaker: Alexander Lazar, MD, PhD, MD Anderson Cancer Center, Houston, TX
Access to Handouts
SC Speaker
Speaker: Melissa Pulitzer, MD, Memorial Sloan Kettering Cancer Center, New York, NY
SC Speaker
Speaker: Jaime Calonje, MD, St. John?s Institute of Dermatology, St. Thomas? Hospital, London, England
Access to Handouts


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