2015 Annual Meeting

Association for Molecular Pathology

2015 Annual Meeting

Room CC Ballroom C, March 22 2015, 7:30pm to 10:30pm

Eric J. Duncavage, Marina Nikiforova, Charles E. Hill, John D. Pfeifer, Maria Arcila, Colin Pritchard

Next-Generation of Pathology: Role of the Pathologist in NGS-Based Personalized Medicine

Educational Objective

In the rapidly evolving era of personalized medicine, next-generation sequencing is an important tool to provide comprehensive analysis of human genome for prediction of disease risk, diagnosis, and therapy response. It is critically important that pathologists become “owners” of this new genomic test by developing expertise in the analysis and interpretation of NGS data, correlating these results with clinical and pathology findings and integrating the data into single diagnostic report that will then inform therapeutic choices. This will allow ensuring that the genome-based clinical testing stays directly under the purview of pathologists and our national organizations. This Companion Meeting focuses on all major aspects of NGS testing important for pathology practice. The topic was chosen by the AMP senior co-moderator, Marina Nikiforova, who was selected by the AMP Training and Education Committee in 2013. The proposal and presenters were reviewed by the committee in the early summer of 2014. This activity was designed for pathologists, pathology residents and fellows. Upon completion of this activity, participants should be better able to:

Understand the technical and clinical applications of next-generation sequencing for the solid tumors, hematological malignancies and cancer predisposition

  • Describe the role of pathologist in facilitating NGS testing
  • Be familiar with sample requirements for genomic testing
  • Understand challenges in sequencing data interpretation and reporting

Session Credits: CME = 3 / SAMs = N/A

Agenda

7:30pm
Companion Meeting Moderator
Speaker: Marina N. Nikiforova, MD, University of Pittsburgh Medical Center, Pittsburgh, PA
Handouts: View PDF
7:30pm
Companion Meeting Moderator
Speaker: Eric J. Duncavage, MD, Washington University, St. Louis, MO
7:30pm
Introduction to Program and Panelists
Speaker: Eric J. Duncavage, MD, Washington University, St. Louis, MO
Handouts: View PDF
7:40pm
Overview of NGS Testing: From Sample Preparation to Data Analysis
Speaker: Charles E. Hill, MD, PhD, Emory University Hospital, Atlanta, GA
Handouts: View PDF
8:05pm
Applications of Next Generation Sequencing in Solid Tumors - Pathologist Prospective
Speaker: John D. Pfeifer, MD, PhD, Washington University School of Medicine, St. Louis, MO
Handouts: View PDF
8:30pm
Utility of NGS and Comprehensive Genomic Profiling in Hematopathology Practice
Speaker: Maria E. Arcila, MD, Memorial Sloan Kettering Cancer Center, New York, NY
Handouts: View PDF
8:55pm
NGS for Cancer Predisposition
Speaker: Colin C. Pritchard MD, PhD, University of Washington, Seattle, WA
Handouts: View PDF
9:20pm
Summary: Future of Pathology in Era of Personalized Medicine
Speaker: Marina Nikiforova, MD, University of Pittsburgh Medical Center, Pittsburgh, PA
Handouts: View PDF
9:40pm
Panel Discussion/Question & Answer

Meetings

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