2016 Annual Meeting

Long Course: Diagnosing Distinctive Lesions of the Head and Neck

Room CC Ballroom 6 A/B/C, March 16 2016, 8:00am to 5:15pm

Description

Long Course: Diagnosing Distinctive Lesions of the Head and Neck
Wednesday, March 16, 2016
8:00 AM- 5:30 PM

Credits: 6 CME and 5.75 SAMs

Course Director: Lester Thompson, MD, Woodland Hills Medical Center, Woodland Hills, CA

Course Description: There has been a remarkable increase in the knowledge about tumors, tumor development and tumor genetics in the past 15 years since the last long course devoted to head and neck pathology. Many new entities have been described, with their diagnostic criteria and ancillary supporting findings elucidated. The differential diagnostic considerations of the head and neck are broad, due in part to the wide diversity of organs, many tissue types, and the often very limited size of biopsy samples. The differences between benign, reactive lesions and lethal malignancies may be quite subtle. The primary goal of this course is to present practical, common, every-day cases across a broad spectrum of anatomic sites, discussing the development of differential diagnoses based on clinical and imaging findings, histologic features and additional techniques that allow for an appropriate diagnosis to be reached. These diagnoses will be put in the context of management and outcome differences, highlighting entities that provoke a broad differential diagnosis. The major topics will include sinonasal tract tumors, newly described and basaloid salivary gland tumors, oropharyngeal carcinomas, lichenoid lesions of the oral cavity, the viral-associated tumors of the nasopharynx, odontogenic cysts and tumors, squamous lesions of the larynx, with a focused discussion on how and when to use molecular and genetic techniques. Information to be included in the 2016-17 WHO classification will be discussed. The lectures are intended for general surgical pathologists, oral pathologists and pathology residents and fellows.

 

8:00 AM An Approach to Diagnosing Small Samples of Round Blue Cell Tumors of the Sinonasal Tract
Lester D.R. Thompson, MD, Woodland Hills Medical Center
Upon completion of this educational activity, participants should be able to:
  1. Develop a clinical, imaging, and histolopathology differential diagnosis for small round blue cell lesions of the sinonasal tract
  2. Understand the fundamental treatment differences between the various diagnosis and how to reach a diagnostic category based on selecting special studies to aid in separation
8:45 AM Newly Described Salivary Gland Tumors
Alena Skalova, MD, PhD, Charles University in Prague, Czech Republic
Upon completion of this educational activity, participants should be able to:
  1. To recognize the characteristic histologic, immunohistochemical and genetic features of diagnostically challenging and newly described tumor entities in salivary gland pathology; in particular mammary analogue secretory carcinoma (MASC), cribiform cystadenocarcinoma of tongue and other minor salivary glands (CATS), and sclerosing polycystic adenoma (SPA)
  2. To describe the differential diagnosis for those entities, emphasizing the benign and low grade malignant possibilities. Discussion of each entity will include histopathological features, differential diagnosis, utility of ancillary studies, impact on surveillance and management, and insight into molecular pathogenesis.
9:30 AM Break
10:30 AM HPV-Related Oropharyngeal Carcinomas- “Catch Me If You Can!”
James Lewis, Jr, MD, Vanderbilt University Medical Center, Nashville, TN
Upon completion of this educational activity, participants should be able to:
  1. Learn the numerous morphologic patterns that HPV-related oropharyngeal carcinomas can display, in the primary and in the neck, and how to recognize them.
  2. Understand the clinical significance for diagnosing these tumors, including the significance of morphologic subtypes.
11:15 AM Oral Lichenoid Lesions: Distinguishing the Benign from the Deadly.
Susan Muller, DMD, Emory University Medical Center, Decatur, GA
Upon completion of this educational activity, participants should be able to:
  1. To distinguish the pathologic findings of oral lichenoid lesions from oral lichen planus.
  2. To recognize the diagnostic criteria of premalignant of oral lichen planus
12:00 PM Lunch
1:00 PM Virus-associated Neoplasms of the Nasopharynx and Sinonasal Tract: Diagnostic Issues
John K-C. Chan, MD, Queen Elizabeth Hospital, Hong Kong
Upon completion of this educational activity, participants should be able to:
  1. To be familiar with the problems in rendering a histologic diagnosis of nasopharyngeal carcinoma, and in particular the mimickers
  2. To be familiar with the problems in diagnosing extranodal NK/T-cell lymphoma, and the differential diagnosis
1:30 PM Basaloid/ Blue Salivary Gland Tumors
Raja R. Seethala, MD, UPMC Presbyterian
Upon completion of this educational activity, participants should be able to:
  1. To apply an algorithmic approach incorporating tumor border, stromal characteristics and cell types to distinguish between various basaloid salivary gland tumors
  2. To use morphologic and immunohistochemical findings to easily delineate polymorphous low grade adenocarcinoma from adenoid cystic carcinoma
2:00 PM How to Diagnose the Most Common Odontogenic and Osseous Lesions of the Jaws
Robert Robinson, MD, PhD, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Upon completion of this educational activity, participants should be able to:
  1. Discriminate between periapical cyst, dentigerous cyst and keratocystic odontogenic tumor utilizing histologic and radiographic criteria
  2. Describe the clinical, radiographic and histologic differences between fibro-osseous lesions of the jaws.
2:30 PM Using Molecular Assays to Resolve Challenging Differentials and Treatment Decisions in Head and Neck Cancers
Jennifer L. Hunt, University of Arkansas for Medical Sciences, Little Rock, AR
Upon completion of this educational activity, participants should be able to:
  1. Understand the benefits and limitations for molecular testing in head and neck cancers
  2. Be able to utilize molecular assays to resolve challenging differential diagnosis in head and neck cancers.
3:00 PM Break
4:15 PM Squamous Cell Carcinoma of the Upper Aerodigestive Tract: Premalignant Lesions, Invasive Carcinoma and Select Variants
Bruce M. Wenig, The Icahn School of Medicine at Mount Sinai, Mount Sinai Beth Israel
Upon completion of this educational activity, participants should be able to:
  1. Identify the diagnostic criteria and clinical relevance for keratinizing intraepithelial dysplasia of the upper aerodigestive tract.
  2. Recognize the features of invasive squamous cell carcinoma and distinguish it from look-alike benign
  3. Identify the clinical and pathologic features for select variants of squamous cell carcinoma.
5:00 PM Wrap- Up
Lester Thompson
Compilation of the course for the day

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