2017 Annual Meeting

Society for Hematopathology

March 5 2017, 1:30pm to 5:00pm


Society for Hematopathology

An Update on Monocytic and Histiocytic Neoplasms and Disorders

Sunday, March 5, 2017
1:30 PM 5:00 PM
CC Hemisfair 2&3

Session Credits: 3 CME and SAMs

Moderators: Michele Paessler, DO, Perelman School of Medicine, Philadelphia, PA
Robert Lorsbach, MD, Cincinnati Children’s Hospital, Cincinnati, OH

Course Description:
The Society for Hematopathology Companion Meeting will focus on neoplasms and reactive disorders of monocytes, histiocytes and dendritic cells. There have been recent, significant advances in our understanding of the pathogenesis and diagnosis of these neoplasms and disorders. Topics to be covered in this session include an update on the recently revised WHO classification of the histiocytoses and neoplasms of the macrophage-dendritic cell lineage, the pathogenesis of juvenile myelomonocytic leukemia, histopathology and genetics of dendritic cell neoplasms, the plasmacytoid dendritc cell neoplasms, the genomics of Langerhans cell histiocytoses and other histiocytic neoplasms, and an update on the pathogenesis and diagnosis of hemophagocytic lymphohistiocytosis. The program includes a panel of expert speakers and will provide an excellent opportunity for participants to update their knowledge of the pathogenesis, genomics and diagnosis of this group of often challenging neoplasms and disorders.

Upon completion of this educational activity, participants should be able to:

  • Describe the recently updated WHO classification of histiocytoses, tumors of macrophage-dendritic cell lineage and juvenile myelomonocytic leukemia
  • Understand the role of immunohistochemistry and molecular testing in the diagnosis and prognostication of the macrophage-dendritic cell neoplasms, including Langerhans cell histiocytosis
  • Describe the pathogenesis of hemophagocytic lymphohistiocytosis (HLH), including the predisposing genetic lesions, and the current diagnostic criteria for HLH


1:30 PM

Updates in JMML
Mignon Loh, MD, PhD, University of California San Francisco, San Francisco, CA

2:00 PM

WHO Has an Update on the HistiocytosisCheck in Your Blood: A Brief Update on Histiocytic Neoplasms and Disorders
Jennifer Picarsic, MD, University of Pittsburgh School of Medicine, Pittsburgh, PA

2:30 PM

Plasmacytoid Dendritic Cell Neoplasms
Fabio Facchetti, MD, PhD, University of Brescia School of Medicine, Brescia, Italy

3:00 PM


3:30 PM

Dendritic Cell Neoplasms: Histology, Immunohistochemistry, and Molecular Genetics
Jason Hornick, MD, PhD, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA

4:00 PM

Rebranding Histiocytic Disorders
Carl Allen, MD, PhD, Baylor College of Medicine and Texas Children’s Cancer Center, Houston, TX

4:30 PM

Hemophagocytic Lymphohistiocytosis: A Unique Immmunoregulatory Disorder
Michael B. Jordan, MD, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH


view more