2017 Annual Meeting

Society for Ultrastructural Pathology

March 5 2017, 8:30am to 12:00pm

Description

Society for Ultrastructural Pathology

Multidisciplinary Approach to the Contemporary Diagnosis of Spindle and Epithelioid Soft Tissue Tumors

Sunday, March 5, 2017
8:30 AM 12:00 PM
CC 303 C

Session Credits: 3 CME and 3 SAMs

Moderators: Guillermo A. Herrera, MD, Louisiana State University Health Sciences, Shreveport, LA
Giovanna Crisi, MD, PhD, Baystate Health, Springfield, MA

Course Description:
The symposium will provide an overview and highlight recent developments in the diagnosis of spindle and epithelioid soft tissue tumors using a multidisciplinary approach. The first half of the symposium will cover characteristic histomorphological features, will present established and new more specific immunohistochemical markers, and will present the current molecular cytogenetics of these tumors. The second half of the symposium will focus on the application and value of ultrastructural pathology as a diagnostic and complementary tool to the workup of spindle and epithelioid soft tissue tumors, and pediatric spindle cell, fibroblastic and myofibroblastic tumors. In the current practice of surgical pathology, the small tissue sample received for diagnostic workup may be insufficient for all modalities. Ultrastructural analysis should be viewed as an important tool to narrow a differential diagnosis. The surgical pathologist should be aware of look-alikes and pitfalls in ultrastructural pathology of spindle and epithelioid tumors.

Upon completion of this educational activity, participants should be able to:

  • Describe the differential diagnosis of spindle and epithelioid soft tissue tumors, and provide an overview of the multidisciplinary approach to render a final diagnosis
  • Identify more specific antibodies that define the line of differentiation of a tumor, its ultrastructural features, and molecular cytogenetic alterations
  • Measure the value of the different diagnostic approaches in establishing a final diagnosis in spindle and epithelioid soft tissue tumors

Agenda

8:30 AM

An Update on the Role of Immunohistochemistry and Molecular Diagnostics in the Evaluation of Spindle Cell Tumors of Soft Tissue
Leona A. Doyle, MD, Brigham and Women’s Hospital, Boston, MA

9:15 AM

Differential Diagnosis of Epithelioid Cell Tumors: The Role of Immunohistochemistry and Molecular Genetics
Andrew L. Folpe, MD, College of Medicine Mayo Clinic, Rochester, MN

10:00 AM

Break

10:30 AM

Value of Electron Microscopy in the Differential Diagnosis of Spindle and Epithelioid Cell Tumors
G. Petur Nielson, MD, Massachusetts General Hospital, Boston, MA

11:00 AM

Look-alikes in Spindle and Epithelioid Tumors: Ultrastructural Value and Pitfalls in Diagnosis
Guillermo A. Herrera, MD, Louisiana State University Health Sciences, Shreveport, LA

11:30 AM

Pediatric Spindle Cell, Fibroblastic and Myofibroblastic Tumors
John Hicks, MD, Texas Children’s Hospital, Baylor College of Medicine, Houston, TX

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