2017 Annual Meeting

SC39-Bone Marrow Manifestations of Systemic Disease

March 9 2017, 1:00pm to 4:30pm

Description

SC39-Bone Marrow Manifestations of Systemic Disease

Session Credits: 3 CME and 3 SAMs

Faculty: Dita Gratzinger, MD, PhD, Stanford Medicine, Stanford, CA, David Czuchlewski MD, University of New Mexico, Albuquerque, NM and C. Tracy George MD, University of New Mexico, Albuquerque, NM

Pathologists evaluating bone marrow biopsies generally focus on identification of hematolymphoid malignancy, with much less awareness of the bone marrow manifestations of systemic disease. Findings of systemic disease in the bone marrow can mimic malignancy, potentially resulting in misdiagnosis; conversely, recognition of systemic disease in the bone marrow can guide clinical management, making recognition of these findings critical for diagnostic pathologists. This case-based course will stress recognition of non-neoplastic systemic disorders manifesting in the bone marrow, including heritable bone marrow failure, storage and immunodeficiency disorders; infection-related marrow abnormalities; drug/toxin-related abnormalities; nutritional, metabolic and endocrine disorders; and rheumatologic/autoimmune disorders. The course is designed for advanced residents, fellows, surgical pathologists and hematopathologists. Case images, along with histories, will be posted on the USCAP website for review by pre-registrants prior to the meeting. A syllabus reviewing diagnostic features and differential diagnosis, and providing a comprehensive reference list will be posted on the USCAP website prior to the meeting. All course registrants will also receive web access to the PowerPoint presented at the USCAP Annual Meeting along with the text portion of the syllabus.

Upon completion of this educational activity, participants will be able to:

  1. Provide a comprehensive differential diagnosis for systemic causes of abnormalities of hematopoiesis and of non-hematopoietic marrow
  2. Be able to identify clinical and laboratory information needed to support non-neoplastic diagnoses in the marrow
  3. Recognize the morphologic findings associated with specific systemic disorders as manifested in the routine diagnostic bone marrow biopsy.

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