2017 Annual Meeting

SC45-Problematic Ductal Proliferations of the Breast

March 10 2017, 1:00pm to 4:30pm


SC45-Problematic Ductal Proliferations of the Breast

Session Credits: 3 CME and 3 SAMs

Melinda F. Lerwill, MD, Massachusetts General Hospital, Boston, MA, Kimberly H. Allison, MD, Stanford University, Stanford, CA, and Kristin C. Jensen, MD, Stanford University, Stanford, CA and Veterans Affairs Palo Alto Health Care System, Palo Alto, CA

The evaluation of benign, atypical, and low-grade malignant intraductal proliferations in the breast is a recurring source of diagnostic difficulty in daily practice. This short course is designed as a highly practical and interactive case-based workshop focusing on commonly encountered problematic ductal proliferations, including micropapillary ductal carcinoma in situ, solid papillary ductal carcinoma in situ, atypical ductal hyperplasia, flat epithelial atypia, apocrine atypia, and mimics of neoplastic atypia. Case discussion will emphasize morphologic features, diagnostic criteria, differential diagnoses, and current clinical implications and management. The utility of ancillary studies will be reviewed where appropriate. Reporting suggestions for difficult cases and practical diagnostic algorithms will be presented. Audience response technology will be utilized to explore key concepts and facilitate discussion. The course is ideal for practicing general surgical pathologists, surgical pathologists with a specialty interest in breast pathology, and pathologists-in-training. Virtual slides and/or still-images and case histories will be available to pre-registrants on the USCAP website prior to the meeting. Case diagnoses, the course syllabus, and PowerPoint presentations will be available electronically on the USCAP website after the course.

Upon completion of this educational activity, participants should be able to:

  1. Recognize the morphologic features and understand the diagnostic criteria for problematic ductal proliferations of the breast
  2. Approach, diagnose, and report challenging borderline cases (e.g., atypical ductal hyperplasia versus low-grade ductal carcinoma in situ), with special consideration for clinical context and implications
  3. Identify especially problematic cases for which second review and/or quality assurance procedures may benefit.


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