Companion Society Meetings

College of American Pathologists

Diagnosis in the Gray Zone: Making the Right Diagnosis in an Evolving Pathologic Landscape

Sunday, March 18, 2018, 8:30 AM - 12:00 PM

Session Credits:



Robert M. Najarian, MD, Beth Israel Deaconess Medical Center, Boston, MA
Donna E. Hansel, MD, PhD, University of California, San Diego, CA

Course Description:

Surgical pathologists increasingly encounter challenging cases where they struggle not only with the identification of pathologic abnormalities, but with changing classification schemata and evolving treatment implications. These factors can significantly impact the patient through under- and over-diagnosis, misunderstanding of such diagnoses by our colleagues, and subsequent effect on patient prognosis and treatment. As the title implies, the faculty will define a practical approach for correctly diagnosing these "gray zone" entities, what to look for, what to report, and when to report it, in four critical areas of surgical pathology.

Learning Objectives:

Upon completion of this educational activity, the learner will be able to:

  • Distinguish the key features between "gray zone" lesions, which present diagnostic challenges for pathologists
  • Interpret the results of ancillary studies, including molecular testing, in the context of clinical and histopathologic features of each entity
  • Develop the best practical approach for the evaluation of "gray zone" lesions leading to the appropriate diagnosis of benign and malignant lesions and the implications of making such diagnoses


8:30 AM The Histologic Spectrum of Proliferative Lesions of the Breast
Jean F. Simpson, MD, Breast Pathology Consultants, Inc., Nashville, TN
9:20 AM Diagnostic Challenges in Endometrial Neoplasia
Oluwole Fadare, MD, University of California, San Diego, CA
10:00 AM Break
10:30 AM Melanocytic Lesions and their Mimickers
Martin C. Mihm, Jr, MD, Brigham and Women's Hospital, Boston, MA
11:15 AM Serrated Neoplasia of the Colon: Controversies, Confusion, and Closure
Robert Najarian, MD, Beth Israel Deaconess Medical Center, Boston, MA


Continuing Medical Education

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of The United States and Canadian Academy of Pathology and College of American Pathologists. The United States and Canadian Academy of Pathology is accredited by the ACCME to provide continuing medical education for physicians.

The United States and Canadian Academy of Pathology designates this live activity for a maximum of
3 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


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