Companion Society Meetings

American Society for Investigative Pathology

Misfolded Proteins, Association with Disease, and Diagnostic Implications

Sunday, March 18, 2018, 1:30 PM

Session Credits:

3 CME and 3 SAMs

Moderators:

Monte S. Willis, MD, PhD, University of North Carolina at Chapel Hill, Chapel Hill, NC
Mark E. Sobel, MD, PhD, American Society for Investigative Pathology, Rockville, MD

Course Description:

Misfolded proteins are an increasing area of research investigation with implications for a range of disorders from diabetes to heart disease to neurologic disorders. The integration of anatomic, molecular, and genomic pathology into surgical pathology practice offers new opportunities for the pathologist to diagnose heart disease and neurological deficits and to consult on possible therapeutic approaches.

Learning Objectives:

Upon completion of this educational activity, the learner will be able to:

  • Describe the new technologies associated with misfolded proteins.
  • Understand how pre-amyloid oligomers are associated with disease.
  • Describe the role of misfolded proteins in pathogenesis and diagnosis of heart disease.
  • Describe the role of misfolded proteins in pathogenesis and diagnosis of neurological disorders.

 

1:30 PM Misfolded Proteins: Introduction and Overview
Mark E. Sobel, MD, PhD, American Society for Investigative Pathology, Rockville, MD
1:35 PM β-Amyloid Oligomers in Aging and Alzheimers Disease
Karen Hsiao Ashe, MD, PhD, University of Minnesota, Minneapolis, MN
2:15 PM Misfolded Proteins in Type 2 Diabetes: A New Therapeutic Target for Intervention in Associated Heart Failure and Neurologic Deficits
Monte S. Willis, MD, PhD, University of North Carolina at Chapel Hill, Chapel Hill, NC
3:00 PM Misfolded Proteins in Heart Failure
Federica del Monte, MD, PhD, Medical University of South Carolina, Charleston, SC
3:40 PM Misfolded Proteins in Heart Disease: Perspectives of a Practicing Cardiac Pathologist
James Stone, MD, PhD, Massachusetts General Hospital and Harvard Medical School, Boston, MA
4:20 PM Final Thoughts on Misfolded Proteins: Panel Discussion
Mark E. Sobel, MD, PhD, American Society for Investigative Pathology, Rockville, MD

 

Continuing Medical Education and Maintenance of Certification

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of The United States and Canadian Academy of Pathology and American Society for Investigative Pathology. The United States and Canadian Academy of Pathology is accredited by the ACCME to provide continuing medical education for physicians.

The United States and Canadian Academy of Pathology designates this live activity for a maximum of
3 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The USCAP is approved by the American Board of Pathology (ABP) to offer Self-Assessment credits (SAMs) for the purpose of meeting the ABP requirements for Maintenance of Certification (MOC). Physicians must take and pass the post-test in order to claim SAMs credit.

Physicians can earn a maximum of 3 SAM credit hours.

 

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