Companion Society Meetings

Society of Ultrastructural Pathology

Pathology of the Nervous System

Sunday, March 18, 2018, 8:30 AM - 12:00 PM

Session Credits:

3 CME and 3 SAMs


Giovananna M. Crisi, MD, PhD, University of Massachusetts Medical School, Baystate, Springfield, MA
Elizabeth N. Pavlisko, MD, Duke University Medical Center, Durham, NC

Course Description:

The selected program aims to present updates on recent developments in several techniques, and current and novel diagnostic approaches available to a variety of peripheral nerve and muscle conditions, with an emphasis on the important role of electron microscopy in neuromuscular diseases.

Electron microscopy has played an important role in defining the fine structural characteristics of central nervous system tumors, and in the diagnosis and the establishment of new tumor entities and variants. However, the use of ultrastructural analysis of brain tumors has decreased with the advent of new techniques e.g. immunohistochemistry. The evolution of the role of EM and its past and current contributions to the diagnoses of central nervous system neoplasia will be presented.

For pathologists currently practicing diagnostic ultrastructural pathology, the session will provide information that can be applied directly to their diagnostic work. For neuropathologists and general pathologists, it will reveal situations in which referral of specimens to a diagnostic EM laboratory would be of value.

Learning Objectives:

Upon completion of this educational activity, the learner will be able to:

  • Assimilate theoretical and practical information on the handling of nerve and muscle biopsies
  • Achieve an understanding of the role of multiple new techniques and approaches to the diagnosis of myopathies and neuropathies
  • Acquire new information on the application and the important diagnostic contributions of EM, enhancing their ability to recognize and interpret diagnostic ultrastructural findings in neuromuscular diseases
  • Understand, by a comprehensive review, the role and utility of electron microscopy in CNS tumors


8:30 AM Peripheral Neuropathy Electron Microscopy
Brent T. Harris, MD, PhD, Georgetown Brain Bank, Georgetown University Medical Center, Washington, DC
9:15 AM Electron Microscopy in Skeletal Muscle Disorders
Anne Buckley, MD, PhD, Duke University Medical Center, Durham, NC
10:30 AM The Role of Electron Microscopy in the Diagnosis and Management of Patients with Lesions of the Pituitary Region: Past, Present and Future
Sylvia L. Asa, MD, PhD, FRCPC, FCAP, FRCPath, University Health Network and University of Toronto, Toronto, ON, Canada
11:15 AM Electron Microscopy in the Diagnosis of CNS Tumors: Dead or Alive?
Caterina Giannini, MD, PhD, Mayo Clinic, Rochester, MN


Continuing Medical Education and Maintenance of Certification

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of The United States and Canadian Academy of Pathology and Society of Ultrastructural Pathology. The United States and Canadian Academy of Pathology is accredited by the ACCME to provide continuing medical education for physicians.

The United States and Canadian Academy of Pathology designates this live activity for a maximum of
3 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The USCAP is approved by the American Board of Pathology (ABP) to offer Self-Assessment credits (SAMs) for the purpose of meeting the ABP requirements for Maintenance of Certification (MOC). Physicians must take and pass the post-test in order to claim SAMs credit.

Physicians can earn a maximum of 3 SAM credit hours.


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