Short Courses and Special Courses

SC08 – The Pathologist’s Role in Guiding Breast Cancer Treatment in the Era of Neoadjuvant Therapy

Friday, March 23, 2018 - 1:00 pm - 4:30 pm
This Short Course session includes up to a 30-minute break.

Session Credits:

3 CME and 3 SAMs


W. Fraser Symmans, MD, The University of Texas MD Anderson Cancer Center, Houston, TX
Veerle Bossuyt, MD, Yale University, New Haven, CT
Elena Provenzano, MD, Addenbrookes Hospital, Cambridge, UK

Course Description

The increasing use of neoadjuvant treatment for advanced and early stage breast cancer has introduced new challenges in the handling and reporting of breast specimens in this clinical context. This practical short course will provide a forum to review and discuss current evidence, and enable general pathologists, pathologists with special expertise in breast pathology, residents, fellows and physician assistants to develop practical approaches for specific scenarios that can be incorporated in routine practice. A combination of short didactic lectures and case studies will set the stage for an interactive discussion. Each participant will have the opportunity to ask questions about specific scenarios posing a dilemma in routine practice. Topics covered will include complete pathologic response, grading of partial response, response in the lymph nodes, evaluation of the axilla before and after treatment, practical approach to sampling of the post- neoadjuvant surgical specimen, detailed method for calculating the residual cancer burden (RCB) score, controversial scenarios and minimum dataset to be reported by the pathologist.

Learning Objectives

Upon completion of this educational activity, the learner will be able to:

  • Recognize and consider the role of pathology reporting in neoadjuvant clinical trials and treatment decisions for individual patients after neoadjuvant therapy
  • Evaluate different pathologic prognostic factors after neoadjuvant therapy
  • Develop a practical approach to the pathologic evaluation of breast specimens following neoadjuvant treatment including gross description, sampling, microscopic evaluation and reporting based on the evidence presented.


Continuing Medical Education and Maintenance of Certification

The United States and Canadian Academy of Pathology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The United States and Canadian Academy of Pathology designates this live activity for a maximum of 3 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The USCAP is approved by the American Board of Pathology (ABP) to offer Self-Assessment credits (SAMs) for the purpose of meeting the ABP requirements for Maintenance of Certification (MOC). Physicians must take and pass the post-test in order to claim SAMs credit.

Physicians can earn a maximum of 3 SAM credit hours.


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